CAS: 52056-69-6; 2-((11-Bromoundecyl)Oxy)Tetrahydro-2H-Pyran

专利信息

专利号:US-7893286-B2
优先权日:2007-06-01
标题 :Method for the synthesis of phospholipid ethers
发明人：PINCHUK ANATOLY; WEICHERT JAMEY P; LONGINO MARC
权利人:CELLECTAR INC
摘要:Disclosed are improved methods for the synthesis of phospholipid ether analogs and alkyl phosphocholine analogs. The methods allow greater versatility of the reactants used and greater ease in synthesizing alkyl chains of varying length while affording reaction temperatures at room temperature or below. The methods disclosed herein provide reactants and conditions using alkyl halides and organozinc reagents and do not utilize Gringard reactions thus, allowing greater ease of their separation and purity of products. The PLE compounds synthesized by the methods disclosed herein can also be used for synthesizing high specific activity phospholipid ether (PLE) analogs, for use in treatment and diagnosis of cancer.

专利号:US-6110906-A
优先权日:1989-03-10
标题:Androgen derivatives for use in the inhibition of sex steroid activity
发明人：LABRIE FERNAND; MERAND YVES
权利人:ENDORECHERCHE INC
摘要:Methods for treating sex steroid-dependent diseases by inhibiting sex steroid activity include administration of novel compounds which include an androgenic nucleus substituted at a ring carbon with at least one substituent specified herein. Such compounds may function by inhibiting sex steroid synthesis (both estrogen and androgen synthesis) and/or by antagonistically blocking androgen receptors.

专利号:US-2008312459-A1
优先权日:2007-06-01
标 题 :Method for the synthesis of phospholipid ethers

专利号:US-5840735-A
优先权日:1988-10-31
标 题:Sex steroid activity inhibitors
发明人：LABRIE FERNAND; MERAND YVES
权利人:ENDORECHERCHE INC
摘要:Inhibitors of sex steroid activity, for example those having the general structure ##STR1## may be used as part of a pharmaceutical composition to provide antiestrogenic effects and/or to suppress estrogen synthesis. Such pharmaceutical compositions are useful for the treatment of breast cancer or other diseases whose progress is aided by activation of sex steroid receptors.

专利号:US-5686465-A
优先权日:1988-10-31
标 题 :Sex steroid activity inhibitors
发明人：LABRIE FERNAND; MERAND YVES
权利人:ENDORECHERCHE INC
摘要:Inhibitors of sex steroid activity, for example those having the general structure ##STR1## may be used as part of a pharmaceutical composition to provide antiestrogenic effects and/or to suppress estrogen synthesis. Such pharmaceutical compositions are useful for the treatment of breast cancer or other diseases whose progress is aided by activation of sex steroid receptors.

专利号:CN-116496289-A
优先权日:2023-04-21
标 题 :Synthesis and application of membrane-targeted naphthalene endoperoxides