CAS: 39691-62-8; Nonylmagnesium Bromide

该化合物是属于Grignard试剂类的有机金属化合物,其特点是存在一个非基类,这是一个长链烷基类组,产自非烷,通过溴原子粘合为镁原子,这种化合物一般是轻黄色液体或固体的无色,视其形态和纯度而定,其表面和纯性而定;非基溴镁具有高度反应性,特别是水和湿度,导致氢气释放和水解过程中形成非基醇;在有机合成中,它通常作为一种核素使用,有助于形成各种反应中的碳-碳联结,例如酒精,金酮和其他功能组的合成;由于具有再活动性,它必须在无水条件下处理,并储存在惰性大气中,以防止分解和不必要反应;在使用这种化合物时,由于易燃性和与 Grignard试管相关的潜在危害,安全防范是不可或缺的.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

1-Bromononane magnesiumHexadecane 4-n-Propyl-tridecan 6-methylpentadecane 2,4-dimethyltridecane

合成工艺路线路线简述

    📜1-溴壬烷 在 Magnesium体系中,用 四氢呋喃作为反应溶剂,获得 Nonylmagnesium Bromide
    参考文献:铁催化酰基氯与格氏试剂的交叉偶联反应.温和,通用,方便地合成脂肪族和芳香族酮.
    标题:铁催化酰基氯与格氏试剂的交叉偶联反应.温和,通用,方便地合成脂肪族和芳香族酮.
    摘要:在催化量的三(乙酰丙酮)铁(III),Fe(Acac)3存在下,室温下将酰氯与格氏试剂偶联.对于两种反应物而言,该反应是通用的,并且提供了用于合成脂族和芳族酮的非常温和且方便的方法.
    Doi:10.1016/S0040-4039(01)81525-2

    海关参考信息

    专利信息


    专利号:US-8535689-B2
    优先权日:2007-10-01
    标题 :Identification of bacterial autoinducer and use in treating bacterial pathogenicity
    发明人:BASSLER BONNIE; SEMMELHACK MARTIN; HIGGINS DOUGLAS A; BOLITHO MEGAN EILEEN; KRAML KRISTINA M; NG WAI-LEUNG
    权利人:BASSLER BONNIE; SEMMELHACK MARTIN; HIGGINS DOUGLAS A; BOLITHO MEGAN EILEEN; KRAML KRISTINA M; NG WAI-LEUNG; UNIV PRINCETON
    摘要:A bacterial autoinducer, CAI-1, was purified and its structure identified. Methods for synthesis of the autoinducer and its analogues were elucidated. Methods of using the autoinducer or its analogues for treating bacterial pathogenicity and bio film formation are described. Methods for prevention and treatment of cholera are described. Synthetic (S)-3-hydroxytridecan-4-one functions as well as natural CAI-1 in repressing production of the virulence factor toxin co-regulated pilus (TCP). Strategies are described to manipulate bacterial quorum sensing in the clinical arena.

    专利号:US-9024045-B2
    优先权日:2012-06-04
    标题 :Process for preparing styrene derivatives
    发明人:GOTTA MATTHIAS; LEHNEMANN BERND WILHELM; VON WANGELIN JACOBI AXEL; GUELAK SAMET
    权利人:SALTIGO GMBH
    摘要:A process is provided which allows the synthesis of a large number of styrene derivatives with formation of C—C bonds, with use being possible of economically advantageous substrates, readily available carbon nucleophiles, and both inexpensive and environmentally unproblematic catalyst systems, permitting reaction under mild conditions and a high compatibility with functional groups on the reactants involved.

    专利号:US-2025059152-A1
    优先权日:2021-12-09
    标 题:Catalytic tetrahydrocannabinol synthesis and precursors
    发明人:ABDUR-RASHID KAMALUDDIN; ABDUR-RASHID KAREEM; JIA WENLI
    权利人:KARE CHEMICAL TECH INC
    摘要:The present disclosure provides new tetrahydrocannabinol precursor compounds and processes to prepare tetrahydrocannabinol compounds. The disclosure also relates to the use of catalysts and catalytic processes for the preparation of tetrahydrocannabinol compounds from the tetrahydrocannabinol precursors. Compounds provided are of formula (I) and (II).

    专利号:CN-109970534-A
    优先权日:2019-04-24
    标题:A method of synthesis sex pheromone of Carposina niponensis

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Ohno, H.; Tomioka, K., Science of Synthesis, (2008) 44, 94.
    参考文献:10.1007/s10886-012-0225-4
    摘要:Fujii T, Yamakawa R, Terashima Y, Imura S, Ishigaki K, Kinjo M, Ando T. Propionates and Acetates of Chiral Secondary Alcohols: Novel Sex Pheromone Components Produced by a Lichen Moth Barsine expressa (Arctiidae: Lithosiinae). Journal of Chemical Ecology. 2012 Dec 19;39(1):28–36. doi: 10.1007/s10886-012-0225-4.
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