CAS: 38361-37-4; 2-Chloro-1,3-Difluorobenzene

上下游产品

CAS号372-18-9 1,3-二氟苯 | CAS号87-61-6 1,2,3-三氯苯 | CAS号34732-09-7 2,3,4-三氯苯磺酰氯 | CAS号372-18-9 1,3-二氟苯 | CAS号1435-44-5 2,4-二氟氯苯 | CAS号107-14-2 氯乙腈 | CAS号367-11-3 邻二氟苯 | CAS号5509-65-9 2,6-二氟苯胺 | CAS号2285-29-2 1,3-difluoro-2-... | CAS号329925-77-1 (2R)-N-(2-chlor... | CAS号1583-58-0 2,4-二氟苯甲酸 | CAS号154257-75-7 3-氯-2,4-二氟苯甲酸

三氯苯置于盐酸,氯磺酸,Potassium Fluoride,硫酸,Sodium Acetate,溶剂黄146体系中,用 环丁砜,水 用作溶剂,化学反应 13.0H,反应生成2,6-二氟氯苯
参考文献:A Convenient Synthesis Of High-Purity 1-Chloro-2,6-Difluorobenzene
标题:A Convenient Synthesis Of High-Purity 1-Chloro-2,6-Difluorobenzene
摘要:A Convenient Preparation Of High-Purity 1-Chloro-2,6-Difluorobenzene Has Been Developed. The Key To The Isolation Of The Desired Isomer,Without Contamination Of The Difficult-To-Separate Isomer 1-Chloro-2,3-Difluorobenzene,Is The Use Of Sulfonyl Chloride To Direct Fluorine Substitution To The Ortho And Para Positions Of The Aryl Ring. Although Activation With Sulfonyl Chloride Requires Additional Reaction Steps,The Process Results In Good Overall Yield And Requires Only Low-Cost Commodity Chemicals. The High-Purity 1-Chloro-2,6-Difluorobenzene Is Useful As An Intermediate For Active Ingredients In Agricultural And Pharmaceutical Applications.
Doi:10.1021/op0340816

专利信息

专利号:US-11213031-B2
优先权日:2017-11-13
标 题:Tetrazolylpropyl derivatives and their use as fungicides
发明人：SUDAU ALEXANDER; HOFFMANN SEBASTIAN; DAHMEN PETER; WEBSTER ROBERT ALAN; MEISSNER RUTH; GOERTZ ANDREAS; MILLER RICARDA; COQUERON PIERRE-YVES; BERNIER DAVID; NICOLAS LIONEL; BRUNET STEPHANE; KENNEL PHILIPPE; TOQUIN VALERIE; GOURGUES MATHIEU; LOQUE DOMINIQUE; THOMAS VINCENT
权利人:BAYER AG; BAYER CROPSCIENCE AG
摘要:The present invention relates to tetrazolylpropyl derivatives of formula (I) n nwherein one of V 1 and V 2 represents CR 3 and the other one of V 1 and V 2 represents N, Q represents a 6-membered aromatic cycle as defined in the specification, and R 1 , R 2 , R 3 , R 4 , and R 5 are defined as disclosed in the specification, to compositions comprising such compounds, to the use of said compounds as fungicides, as well as to particular intermediates useful in the synthesis of said tetrazolylpropyl derivatives.

专利号:RU-1806128-C
优先权日:1991-05-12
标题 :Method of 2,6-difluorobenzoyl chloride synthesis