CAS: 31642-67-8; Non-8-Enoic Acid

相似化合物

13038-21-6 112-38-9 17351-34-7

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CAS号13038-21-6 8-壬烯-1-醇 | CAS号124-38-9 二氧化碳 | CAS号2695-48-9 8-溴-1-辛烯 | CAS号50338-49-3 1-Trimethylsilo... | CAS号5048-34-0 8-Nonenenitrile | CAS号35194-39-9 8-壬酸乙酯 | CAS号39200-19-6 nona-3,8-dienoi... | CAS号4117-09-3 7-溴-1-庚烯 | CAS号505-48-6 辛二酸 | CAS号111-16-0 庚二酸 | CAS号20731-23-1 8-壬酸甲酯 | CAS号35194-39-9 8-壬酸乙酯 | CAS号13038-21-6 8-壬烯-1-醇 | CAS号13038-22-7 乙酸8-壬烯基酯 | CAS号14811-73-5 9-甲酰基壬酸甲酯 | CAS号5578-80-3 Decanoic acid, ...

7-溴-1-庚烯置于正丁基锂,Ammonium Cerium(Iv) Nitrate,Sodium Hydride体系中,用 四氢呋喃,正己烷,乙腈 作为反应溶剂,化学反应 6.33H,反应生成 8-壬烯酸
参考文献:β-二酮和β-酮酸酯轻度转化为羧酸
标题:β-二酮和β-酮酸酯轻度转化为羧酸
摘要:描述了在can 3 Cn中使用can将β-酮酸酯和β-二酮转化为羧酸的温和方案.该方法与许多官能团相容,并且可以在室温下在中性条件下反应生成羧酸.该反应快速且通用,为常用的丙二酸酯制备提供了另一种方法.初期机理研究表明,β-二羰基烯醇形式的初始氧化可引发反应.硝酸盐作为氧化剂的配体或添加剂的存在对于反应成功至关重要.
DOI:10.1021/jo0602975

专利信息

专利号:US-2025136887-A1
优先权日:2021-08-25
标题:Method for the preparation of omega-amino-carboxylic acids and derivatives thereof
发明人：VECCHINI NICOLA; NODARI MIRCO; GALEOTTI ARMANDO; DELLEDONNE DANIELE
权利人:VERSALIS SPA
摘要:A Method for the synthesis of ω-amino acids or derivatives thereof, includes the following steps synthesis of an ω-oxoester/linear acid by hydroformylation by CO/H2 mixture of at least one monounsaturated acid/ester, the monounsaturated acid/ester preferably resulting from a reaction of metathesis of oils/fats from renewable sources; synthesis of a linear ω-amino acid/ester and/or ω-aminoamide, subjecting the aforementioned ω-oxoester/linear acid to reductive amination; and possible synthesis of a linear ω-amino acid, subjecting the aforementioned linear ω-aminoester and/or ω-aminoamide to hydrolysis.

专利号:US-10100028-B2
优先权日:2013-09-30
标 题:Synthesis routes for prostaglandins and prostaglandin intermediates using metathesis
发明人：YIANNIKOUROS GEORGE PETROS; KALARITIS PANOS; GAMAGE CHAMINDA PRIYAPUSHPA; AREFYEV DENIS VIKTOROVICH
权利人:IRIX PHARMACEUTICALS INC; PATHEON API SERVICES INC
摘要:Methods of synthesizing prostaglandins, prostaglandin analogs and their synthetic intermediates are described. The methods can comprise metal-catalyzed metathesis reactions. Also provided are synthetic intermediates that can be used in the synthesis of the prostaglandins and prostaglandin analogs.

专利号:US-8476471-B2
优先权日:2009-07-13
标 题 :Synthesis of prostanoids
发明人：YIANNIKOUROS GEORGE PETROS; KALARITIS PANOS; GAMAGE CHAMINDA PRIYAPUSHPA; ABERNATHY STEPHANIE BOSSE
权利人:YIANNIKOUROS GEORGE PETROS; KALARITIS PANOS; GAMAGE CHAMINDA PRIYAPUSHPA; ABERNATHY STEPHANIE BOSSE; IRIX PHARMACEUTICALS INC
摘要:The presently disclosed subject matter provides a method of synthesizing prostaglandins and prostaglandin analogs comprising the ring closing metathesis of compounds of Formula (I). Also provided are novel compounds of Formula (I) and Formula (II). In addition to their use as synthetic intermediates in the presently disclosed methods, compounds of Formula (II) can be used as prostaglandin and/or prostaglandin analog prodrugs.

专利号:US-2012095211-A1
优先权日:2010-09-22
标 题 :Substituted proline inhibitors of hepatitis c virus replication
发明人：BUCKMAN BRAD; NICHOLAS JOHN B; SEREBRYANY VLADIMIR; SEIWERT SCOTT D
权利人:BUCKMAN BRAD; NICHOLAS JOHN B; SEREBRYANY VLADIMIR; SEIWERT SCOTT D; INTERMUNE INC
摘要:The embodiments provide compounds of the general Formulae I, Ia, II, IIa, III, IIIa, IIIb, IV, IVa, IVb, V, Va, Vb, VI, VIa, VIb, and VIc, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition. The embodiments also provide methods for the synthesis of subject compounds and intermediates in the synthetic methods.

专利号:EP-2454227-B1
优先权日:2009-07-13
标 题 :Synthesis of prostanoids

专利号:WO-2011008756-A1
优先权日:2009-07-13
标题 :Synthesis of prostanoids