CAS: 25569-80-6; 2,3'-Dichloro-1,1'-Biphenyl
该化合物是一种氯化联苯化合物,其特点是在双联苯结构的2和3位置上存在氯原子,这种有机氯化合物主要用于研究和工业应用,特别是用作研究多氯联苯污染的环境和分析化学参考标准,其明确的结构和稳定性使其适合用于色谱分析,毒性研究和降解实验.该化合物的高度纯度和一贯性能确保了方法开发和质量控制的可靠结果.由于其持久性,处理需要遵守安全议定书,以尽量减少环境和健康风险.
- 英文名称2,3'-Dichloro-1,1'-Biphenyl
- 中文名称2,3'-二氯-1,1'-联苯
- IUPAC名称1-chloro-2-(3-chlorophenyl)benzene
- 其它别名Biphenyl,2,3'-dichloro- (7CI,8CI); 2,3'-Dichlorobiphenyl; PCB 6
- CAS编号25569-80-6
- MFCD编号:MFCD00152398
- FDA UNII编号:VZ4O46M8F5
- 分子式:C12H8Cl2分子量:223.1
- 产品CID: 1217538
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
- 相似结构搜索
- 产品信息参考
- InChIKey: ZHBBDTRJIVXKEX-UHFFFAOYSA-N
- 1S/C12H8Cl2/c13-10-5-3-4-9(8-10)11-6-1-2-7-12(11)14/h1-8H
- 计算化学: 氢键受体数*氢键供体数0可旋转键数1
相似化合物
2051-60-7 34883-43-7 37680-68-5物理性质
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
chlorobenzene phenol 2-iod°Chlorobenzene norbornene biphenyl-2,3'-dicarboxylic acid合成工艺路线路线简述
📜Dibenzo[b,D]Chlorol-5-Ium Tetrafluoroborate置于四丁基氯化铵,Caesium Carbonate体系中,用 四氢呋喃 用作溶剂,以99 %的收率获得2,3'-二氯联苯
参考文献:轻松获得多卤联芳基化合物:高价溴和氯的区域选择性(二)卤化
标题:轻松获得多卤联芳基化合物:高价溴和氯的区域选择性(二)卤化
摘要:多卤联芳基是独特的基序,作为复杂联芳基化合物的便捷合成的通用构建模块,具有未开发的潜力.克服了传统合成的局限性,我们引入了一种新颖的,无金属的,操作简单的一锅法,使用环状联芳基高价溴和氯底物作为掩蔽芳炔,在温和条件下区域选择性(二)卤化联芳基化合物.通过化学选择性后功能化,这些有价值的产品可以扩展合成含联芳基支架的工具箱,解决该领域的关键空白.
Doi:10.1039/d4Sc01234H
海关参考信息
- 2903919090-氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-6960601-B2
优先权日:2001-09-24
标题 :Preparation and use of imidazole derivatives for treatment of obesity
发明人：SMITH ROGER A; O'CONNOR STEPHEN J; WIRTZ STEPHAN-NICHOLAS; WONG WAI C; CHOI SOONGYU; KLUENDER HAROLD C E; SU NING; WANG GAN; ACHEBE FURAHI; YING SHIHONG
权利人:BAYER PHARMACEUTICALS CORP
摘要:This invention relates to substituted imidazole derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L135: International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.
摘要:T6: World Health Organization (1993). Environ Health Criteria 140: Polychlorniated Biphenyls and Terphenyls.
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