CAS: 2252-51-9; 2-Chloro-4-Fluorobenzoic Acid

上下游产品

CAS号452-73-3 2-氯-4-氟甲苯 | CAS号625-98-9 间氯氟苯 | CAS号700-35-6 2-氯-4-氟苯乙酮 | CAS号456-22-4 对氟苯甲酸 | CAS号65-85-0 苯甲酸 | CAS号85953-29-3 2-氯-4-氟苯甲酸甲酯 | CAS号21900-54-9 2-氯-4-氟苯甲酰氯 | CAS号625-98-9 间氯氟苯 | CAS号76568-02-0 氟司喹南 | CAS号128992-62-1 4-氟-2-(甲基氨基)苯甲酸 | CAS号101329-81-1 (2-chloro-4-flu... | CAS号101329-82-2 (5-amino-2-chlo... | CAS号154639-75-5 1-[4-fluoro-2-(...

3-氯氟苯置于三氯化铝,Sodium Hypobromide体系中,用 二硫化碳 用作溶剂,化学反应生成2-氯-4-氟苯甲酸
参考文献:516.一些卤原子不同的二卤代苯的乙酰化作用
标题:516.一些卤原子不同的二卤代苯的乙酰化作用
摘要:
Doi:10.1039/jr9630002784

专利信息

专利号:WO-2024047648-A1
优先权日:2022-08-31
标题 :Preparation of 2-chloro-4-fluoro-5-nitrobenzoic acid
发明人：GRABARNICK MICHAEL; GALGE REVANAPPA VASANTRAO
权利人:ADAMA AGAN LTD
摘要:The present invention relates to a novel nitration process of 2- chloro-4- fluorobenzoic acid or alkyl 2-chloro-4- fluorobenzoate, using oleum and nitric acid, to obtain 2-chloro-4- fluoro-5- nitrobenzoic acid or alkyl 2-chloro-4-f luoro-5-nitrobenzoates; purifying the crude reaction product; and recovering 2-chloro-4- fluoro- 5-nitrobenzoic acid or alkyl 2-chloro-4- fluoro-5- nitrobenzoates in an essentially pure form, which can be used in the synthesis of the herbicide saflufenacil.

专利号:US-2025115560-A1
优先权日:2021-08-09
标 题:A new process of saflufenacil production using novel intermediates
发明人：GRABARNICK MICHAEL; JHA ASHOK KUMAR; GALGE REVANAPPA VASANTRAO
权利人:ADAMA AGAN LTD
摘要:The invention relates to a novel and efficient saflufenacil synthesis and the preparation of novel key intermediates in the process of Saflufenacil synthesis. The process includes preparing compounds of the Formula I wherein R1i is a hydrogen, C1-12 straight or branched alkyl, which may be substituted with 1 or more substituents, a C3-10 cycloalkyl, which may be substituted with 1 or more substituents, a C6-10 aromatic ring which may be substituted with 1 or more substituents, a C5-10 heteroaromatic ring, which may be substituted with 1 or more substituents; R2 is a hydrogen or methyl.

专利号:US-2022363662-A1
优先权日:2021-04-20
标题 :Compounds as lxr agonists
发明人：PUJALA BRAHMAM; SATHE BALAJI DASHRATH; DANODIA ABHINANDAN; GUPTA ASHU; SONI SANJEEV; KUMAR VIVEK; ANSARI AMANTULLAH; KHAN FARHA; SARKAR ARINDAM; PAYGHAN PAVAN V
权利人:INTEGRAL BIOSCIENCES PRIVATED LTD
摘要:The present invention generally discloses compounds having LXR (the liver X receptor) agonistic activity, to the use of such compounds in the treatment of various disorders such as proliferative disorders, Alzheimer's disease, inflammatory diseases, and diseases characterized by defects in cholesterol and lipid metabolism. Specifically, the present invention discloses compound of formula (IA) which exhibit LXR agonist activity, specifically to LXRβ. The invention also discloses method of synthesis of said compounds, method of using said compounds, pharmaceutical compositions comprising said compounds and method of using thereof.

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:EP-1853548-B1
优先权日:2005-02-22
标 题:Process for the preparation of benzoic acid derivatives via a new intermediate of synthesis
发明人：MONDINI SIMONETTA; DALL AVA MIRCO; GUERRATO ALFREDO
权利人:MITENI SPA
摘要:The object of the invention is the preparation of 2-chloro-4-fluoro-5-nitrobenzoic acid and derivatives thereof, by nitration of 2-chloro-4-fuorobenzotrichloride and the conversion of the novel synthetic intermediate thus obtained into its acid form or derivatives thereof; a further object of the invention is the conversion of benzotrichloride synthetic intermediates into the corresponding benzotrifluoride derivatives.

专利号:US-2018319832-A1
优先权日:2014-03-15
标题:Design, Synthesis, and Biological Activity of Platinum-benz[c]acridine Hybrid Agents and Methods Associated Therewith