欧盟法规
ECHA物质ECHA物质C&L通报REACH预注册上下游产品
正辛基环己烷 1-Cyclohexyloctane 1795-15-9
烯丙基环戊烷 Allylcyclopentane 3524-75-21-N-丙基环戊醇置于乙醇,氢气,镍体系中,250.0 °C,24.51 Mpa 条件下,反应生成正丙基环戊烷
参考文献:The Preparation Of Cyclopentenes And Cyclopentanes. I1
标题:The Preparation Of Cyclopentenes And Cyclopentanes. I1
摘要:
Doi:10.1021/ja01224A002
专利信息
专利号:US-6184168-B1
优先权日:1997-09-22
标题:Synthesis of 1,4-trans-polybutadiene using a lanthanide organic acid salt catalyst
发明人:LYNCH THOMAS J
权利人:BRIDGESTONE CORP
摘要:The invention provides a catalyst composition, comprising: (a) an organolithium compound; and, (b) an organic acid salt of lanthanide series element; wherein: (1) only components (a) and (b) are required to promote the synthesis of 1,4-trans-polybutadiene; (2) the ratio of component (a) to component (b) is selected to maximize formation of the trans structure of said 1,4-trans-polybutadiene; and, (3) components (a) and (b) are selected for enabling further diblock synthesis. The invention further contemplates a process for using the catalyst to synthesize 1,4-trans-polybutadiene and other polymers and copolymers having trans configuration in the conjugated diene monomer contributed units.
专利号:US-2003162992-A1
优先权日:2001-12-14
标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
发明人:WATANABE KYOICHI A; DU JINFA
摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.
专利号:US-9597327-B2
优先权日:2005-05-25
标 题:Synthesis of (R)-N-methylnaltrexone
发明人:DOSHAN HAROLD D; PEREZ JULIO
权利人:PROGENICS PHARM INC
摘要:This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.
专利号:US-8093378-B2
优先权日:2006-04-28
标题 :Crystallization method for intermediates of carbapenem antibiotics
发明人:NISHINO KEITA; KOGA TERUYOSHI; FUKAE MASAFUMI; UEDA YASUYOSHI
权利人:NISHINO KEITA; KOGA TERUYOSHI; FUKAE MASAFUMI; UEDA YASUYOSHI; KANEKA CORP
摘要:An improved crystallization method for an azetidinone compound represented by the formula 1: , which is extremely useful as a common intermediate for the synthesis of 1β-methylcarbapenem compounds. The present method provides crystals having higher quality and stability than conventional crystals and excellent filterability at the time of recovery; and an azetidinone compound having a low content of impurity, and which has a controlled particle size distribution of crystals and improved handleability and stability. The crystallization is carried out by adding a hydrocarbon solvent to a solution in which an azetidinone compound extremely useful as a common intermediate for the synthesis of 1β-methylcarbapenem compounds is dissolved in the presence of a seed crystal in an amount of 200% by weight or less based on the weight of the azetidinone compound.
专利号:US-4894385-A
优先权日:1985-01-16
标 题:Imidazole derivatives as inhibitors of TXA2 synthesis
发明人:KAWAMOTO ISAO; ENDO ROKURO; MATSUDA KEIICHI; USHIYAMA SHIGERU; OSHIMA TAKESHI
权利人:SANKYO CO
摘要:Compounds of formula (I): ##STR1## (wherein n is 0, 1 or 2 and R 1 , R 2 , R 4 , R 5 , R 6 , X, Y and Z are a variety of groups and atoms) have the ability to inhibit the synthesis of thromboxane A 2 and hence are useful in the treatment or prophylaxis of thrombotic conditions.
专利号:US-6608196-B2
优先权日:2001-05-03
标题 :Process for solid supported synthesis of pyruvate-derived compounds
发明人:WANG BING; JANAGANI SATYANARAYANA; CALLAWAY WYETH B; SESSLER JONATHAN L
权利人:GALILEO PHARMACEUTICALS INC
摘要:Provided are processes for synthesizing structurally diverse pyruvate-derived compounds using a parallel approach on a solid phase support. Examples of such a solid phase support include resins which have also been used in solid phase peptide synthesis.