CAS: 18856-63-8; 4-Ethylphenyl Isothiocyanate

该化合物是一种有机化合物,其特征为功能性异硫氰酸酯组(-N=C=S),附于一个4-乙基苯协会,该化合物通常用于有机合成和制药研究,因为它作为电极的活性,能够形成硫尿素衍生物和其他含有硫磺的外生循环,其结构特性使它在农用化学,生物活性分子和材料科学应用的开发中具有价值.乙基替代成分可增强脂性,有可能提高非极溶剂的溶性.由于乳胶和刺激性特性,需要小心处理,通常储存在惰性条件下,以防止降解.

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CAS号463-71-8 硫光气 | CAS号589-16-2 4-乙基苯胺 | CAS号89573-81-9 1,3-bis(4-ethyl... | CAS号95167-89-8 N-(4-ethyl-phen... | CAS号93693-01-7 4-4 -乙苯基-3-氨基硫脲 | CAS号22265-78-7 1-(对乙基苯基)-2-硫脲

合成工艺路线路线简述

    📜1,3-双(4-乙基苯基)硫脲置于盐酸,磷酸,Phosphorus Pentoxide体系中,化学反应生成4-乙基异硫氰酸苯酯
    参考文献:Mainzer,Chemische Berichte,1883,Vol. 16,P. 2017
    标题:Mainzer,Chemische Berichte,1883,Vol. 16,P. 2017

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    专利信息


    专利号:US-8062756-B2
    优先权日:2005-08-26
    标题:Stepwise growth of oligomeric redox-active molecules on a surface without the use of protecting groups
    发明人:BOCIAN DAVID F; LINDSEY JONATHAN S; JIAO JIEYING
    权利人:BOCIAN DAVID F; LINDSEY JONATHAN S; JIAO JIEYING; REGENTS OFT THE UNIVERSITY OF CALIFORNIA; UNIV NORTH CAROLINA STATE
    摘要:This invention provides a procedure for growing oligomers via a stepwise process. The oligomers can include porphyrins, which have been previously shown to be attractive candidates for molecular-based information storage. The stepwise synthesis procedure requires no protecting groups, thus eliminating protection/deprotection reactions that add complexity to the process.

    专利号:US-9028800-B2
    优先权日:2007-01-11
    标 题 :Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
    发明人:D SOUZA CHRISTOPHER A; MCBRIDE WILLIAM J; GOLDENBERG DAVID M
    权利人:IMMUNOMEDICS INC
    摘要:The present application discloses compositions and methods of synthesis and use of 18 F or 19 F-labeled molecules of use in PET, SPECT and/or MR imaging. Preferably, the 18 F or 19 F is conjugated to a targeting molecule by formation of a complex with a group IIIA metal and binding of the complex to a bifunctional chelating agent, which may be directly or indirectly attached to the targeting molecule. In other embodiments, the 18 F or 19 F labeled moiety may comprise a targetable construct used in combination with a bispecific antibody to target a disease-associated antigen. The disclosed methods and compositions allow the simple and reproducible labeling of molecules at very high efficiency and specific activity in 30 minutes or less. In preferred embodiments, the labeled molecule may be used for imaging in a subject without purification after labeling.

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    合成参考文献


    摘要:Sato, S.; Furukawa, N., Science of Synthesis, (2005) 18, 910.
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