CAS: 14885-29-1; 2-Isopropyl-1-Methyl-5-Nitro-1H-Imidazole

该化合物是一种合成化合物,主要用作抗蛋白剂,特别是用于治疗诸如Giardia和Trichomonas等原生动物引起的感染的兽医药物,属于硝基甲基甲醚,其特点是硝基甲醚组和imidazole环状结构;Ipronidazole具有抗微生物特性,对厌氧细菌和某些寄生虫有效;该化合物通常以口服方式施用,以其在治疗剂量中的毒性相对较低而著称;其行动机制包括减少硝基苯组,导致形成反应性中间体,损害目标生物的DNA;还注意到该物质在不同条件下保持稳定,适合不同药物制剂的配方;然而,与许多药物一样,必须明智地使用该物质防止目标生物体的抗药性发展;在使用该化学物质时,必须正确处理和遵守安全准则.

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上下游产品

diazomethane (5)-nitro-(1H)-imidazole2-isopropyl-4(5)-nitro-(1H)-imidazoleN-(2-Isopropyl-1-methylimidazol-5-yl)-N-phenylthiourea 1-(2-isopropyl-1-methylimidazol-5-yl-)ureaN-(3-Chloro-4-tolyl)-N1-(2-isopropyl-1-methylimidazol-5-yl-)urea 1-(2-isopropyl-1-methylimidazol-5-yl)ureaN-(3,4-Dichlorophenyl)-N1-(2-isopropyl-1-methylimidazol-5-yl)urea 1-(4-tolylsulfonyl)ureaN-(2-isopropyl-1-methylimidazol-5-yl)-N1-(4-tolylsulfonyl)urea

合成工艺路线路线简述

    📜2-异丙基-1-甲基-1H-咪唑 反应生成异丙硝唑
    参考文献:Maksimovic,R.;Dusanovic,D.;Radovic,N.
    标题:Maksimovic,R.;Dusanovic,D.;Radovic,N.

    海关参考信息

    专利信息


    专利号:US-2014315720-A1
    优先权日:2012-10-24
    标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
    发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
    权利人:CELANESE ACETATE LLC
    摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:S72 | NTUPHTW | Pharmaceutically Active Substances from National Taiwan University | DOI:10.5281/zenodo.3955664
    摘要:https://www.sciencedirect.com/science/article/abs/pii/S0003267018311693
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