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140-04-5 151-13-3 36781-75-6欧盟法规
REACH注册ECHA物质C&L通报REACH预注册上下游产品
CAS号67-56-1 甲醇 | CAS号141-24-2 蓖麻油酸甲酯 | CAS号75-36-5 乙酰氯 | CAS号108-22-5 醋酸异丙烯酯 | CAS号41989-07-5 12-羟基油酸甲酯 | CAS号108-24-7 乙酸酐 | CAS号141-22-0 蓖麻油酸📜甲醇,12-Acetylricinoleic Acid置于对甲苯磺酸体系中,化学反应 4.0H,以73%的收率获得o-乙酰基蓖麻酸甲酯
参考文献:Antioxidant,Anti-Inflammatory And Anti-Hyperglycaemic Activities Of Heterocyclic Homoprostanoid Derivatives
标题:Antioxidant,Anti-Inflammatory And Anti-Hyperglycaemic Activities Of Heterocyclic Homoprostanoid Derivatives
摘要:A Series Of 19 Heterocyclic Homoprostanoids Were Synthesized From Easily Available Oleic And Ricinoleic Acids And Evaluated For Their Possible Antioxidant,Anti-Inflammatory And Anti-Hyperlipidaemic Activities. Compounds With Thioxo-And Oxoimidazole Ring (1) And (2) Have Shown Potent Antioxidant Activity With Ic(50) Values 0.23 +/-0.09 And 0.41 +/-0.01 Mm Comparable With Standard Ascorbic Acid. Compound (3) With A Quinoxaline Ring Showed Maximum Inhibition Of Bsa Denaturation At 1 Mm Concentration And Comparable With Standard Diclofenac. Incorporation Of Electron Withdrawing Substitutions Like Chloro-And Nitro-Groups In The Quinoxaline Ring Has Resulted In An Increase Anti-Inflammatory Activity. Test Compounds (3),(3A) And (3C) Showed Modest Inhibition Of Dpp-Iv In Vitro. However,The Unsubstituted Quinoxaline (3) And Substituted Quinoxalines (3B And 3C) Reduced Plasma Glucose Levels Indicating The Presence Of Hypoglycemic Activity. (C) 2010 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Bmc.2010.11.016
海关参考信息
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专利信息
专利号:US-7176336-B2
优先权日:2003-10-09
标题 :Process for the synthesis of unsaturated alcohols
发明人:MAUGHON BOB R; BURDETT KENNETH A; LYSENKO ZENON
权利人:DOW GLOBAL TECHNOLOGIES INC
摘要:A process of preparing an unsaturated alcohol (olefin alcohol), such as, a homo-allylic mono-alcohol or homo-allylic polyol, involving protecting a hydroxy-substituted unsaturated fatty acid or fatty acid ester, such as methyl ricinoleate, derived from a seed oil, to form a hydroxy-protected unsaturated fatty acid or fatty acid ester; homo-metathesizing or cross-metathesizing the hydroxy-protected unsaturated fatty acid or fatty acid ester to produce a product mixture containing a hydroxy-protected unsaturated metathesis product; and deprotecting the hydroxy-protected unsaturated metathesis product under conditions sufficient to prepare the unsaturated alcohol. Preferably, methyl ricinoleate is converted by cross-metathesis or homo-metathesis into the homo-allylic mono-alcohol 1-decene-4-ol or the homo-allylic polyol 9-octadecene-7,12-diol, respectively.
专利号:CA-2541263-A1
优先权日:2003-10-09
标 题:An improved process for the synthesis of unsaturated alcohols
专利号:US-2005080301-A1
优先权日:2003-10-09
标 题:Process for the synthesis of unsaturated alcohols
专利号:WO-2005040077-A2
优先权日:2003-10-09
标题 :An improved process for the synthesis of unsaturated alcohols
专利号:EP-1673328-A2
优先权日:2003-10-09
标 题:An improved process for the synthesis of unsaturated alcohols
专利号:EP-1673328-B1
优先权日:2003-10-09
标题:An improved process for the synthesis of unsaturated alcohols