CAS: 13534-97-9; 6-Bromopyridin-3-Amine

相似化合物

218594-15-1 4487-59-6 39856-57-0

上下游产品

CAS号4487-59-6 2-溴-5-硝基吡啶 | CAS号7439-89-6 铁粉 | CAS号462-08-8 3-氨基吡啶 | CAS号5418-51-9 2-羟基-5-硝基吡啶 | CAS号4214-76-0 2-氨基-5-硝基吡啶 | CAS号1067877-78-4 5-溴噻唑并[5,4-b]吡啶... | CAS号55717-45-8 2-溴-5-羟吡啶 | CAS号142946-80-3 5,5'-二(三氟甲基)-2,... | CAS号915006-52-9 5-氨基-2-溴-6-碘吡啶 | CAS号462-08-8 3-氨基吡啶 | CAS号29958-08-5 6-(甲硫基)吡啶-3-胺 | CAS号934266-82-7 5-溴噻唑并[5,4-b]吡啶-2-胺 | CAS号218594-15-1 2-溴-5-B°C-氨基砒啶 | CAS号6188-23-4 6-溴-咪唑并[1,2-a]吡啶 | CAS号73290-22-9 2-溴-5-碘吡啶

2-羟基-5-硝基吡啶置于盐酸,磷化氢,溴,甲苯,Tin(Ll) Chloride体系中,化学反应生成5-氨基-2-溴吡啶
参考文献:Yamamoto,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1951,Vol. 71,P. 662,665
标题:Yamamoto,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1951,Vol. 71,P. 662,665

专利信息

专利号:US-7884125-B2
优先权日:2008-04-30
标 题:Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues
发明人：STEVENS CHRISTIAN; HEUGEBAERT THOMAS
权利人:UNIV GENT
摘要:The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter-gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction.

专利号:US-2009275616-A1
优先权日:2008-04-30
标 题 :Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues

专利号:US-9856241-B2
优先权日:2013-07-03
标 题:Substituted benzofuranyl and benzoxazolyl compounds and uses thereof
发明人：BALOGLU ERKAN; SHACHAM SHARON; SENAPEDIS WILLIAM; MCCAULEY DILARA; LANDESMAN YOSEF; GOLAN GALI; KALID ORI; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to substituted benzofuranyl and substituted benzoxazolyl compounds, and more particularly to a compound represented by Structural Formula (A): or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of Structural Formula (A), or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders.

专利号:CN-111170991-B
优先权日:2014-07-11
标题 :Antiproliferative compounds and methods of synthesis thereof

专利号:CN-117447469-A
优先权日:2023-10-27
标题:A continuous flow synthesis method for key intermediates of MELK inhibitors

专利号:US-8791131-B2
优先权日:2008-09-30
标题 :Imidazo[1,5]naphthyridine compounds, their pharmaceutical use and compositions
发明人：CHENG HENGMIAO; JOHNSON TED WILLIAM; HOFFMAN JACQUI ELIZABETH; GUO LISA CHEN; LIU ZHENGYU
权利人:CHENG HENGMIAO; JOHNSON TED WILLIAM; HOFFMAN JACQUI ELIZABETH; GUO LISA CHEN; LIU ZHENGYU; PFIZER
摘要:The present invention is directed to compounds of Formula (I), n nand to salts thereof, their synthesis, and their use as PI3-Kα inhibitors and/or PI3-Kα/mTOR dual inhibitors.