CAS: 117358-52-8; 1-Ethyl-3,5-Difluorobenzene

该化合物是一种芳香化合物,其特点是乙基组和两个氟原子附于苯环,乙基组位于第一个位置,氟替代成分位于苯环的第三和第四碳,这增加了其独特的化学特性.该化合物一般是一种无色液体,在室温下,与其他替代苯相比,其沸点相对较低,因为氟原子的影响是电阴性的,能够影响化合物的极度和再活动.氟的存在可增强化合物的稳定性,影响其与其他物质的相互作用,使其在各种化学应用中具有兴趣,包括溶剂或更为复杂的有机分子的合成.此外,该化合物的结构可能具有诸如水分和潜在生物活动等具体特征,这些特征可能与制药和农用化学等领域有关.

英文名称1-Ethyl-3,5-Difluorobenzene
中文名称3,5-二氟乙苯
IUPAC名称1-ethyl-3,5-difluorobenzene
其它别名3,5-二氟基苯; 1-Ethyl-3,5-Difluorobenzene3,5-Difluoro-Ethyl Benzene
CAS编号117358-52-8
MFCD编号:MFCD10000628
EINECS号:694-579-2
分子式:C8H8F2
分子量:142.15
产品CID: 221802
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: PFINYKRPUJCMCT-UHFFFAOYSA-N
InChI=1S/C8H8F2/c1-2-6-3-7(9)5-8(10)4-6/h3-5H,2H2,1H3…
计算化学: 氢键受体数0.0氢键供体数0可旋转键数1

相似化合物

459-47-2 28593-12-6 117358-51-7

MSDS等安全信息

GHS象形图
GHS符号GHS02 & GHS07;
注释: Flame & Exclamation mark
危险类别易燃液体类别3
急性毒性类别4(经口)
警示词Warning(警告)
危险描述H226 |易燃液体和蒸气.
H302 |吞咽有害.
防范说明P210-P233-P240-P241-P242-P243-P264-P270-P280-P330-P370+P378-P501
危险等级3
UN编号1993.0
危险品标志Xn
包装等级Ⅲ
安全声明H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
危险类别码10-22
WGK Germany3

欧盟法规

C&L通报

合成工艺路线路线简述

[1-(3,5-Difluoro-Phenyl)-Ethyl]-Methyl-Amine置于palladium On Activated Charcoal 氢气体系中,用甲醇用作溶剂,60.0 °C,500.0 Kpa 条件下,反应 6.0H,以0.2%的收率获得1-乙基-3,5-二氟苯
参考文献:通过延迟苄位氢解裂解实际合成光学活性氟取代的 α-苯乙胺
标题:通过延迟苄位氢解裂解实际合成光学活性氟取代的 α-苯乙胺
摘要:在芳环上具有氟原子的双(α-甲基苄基)胺氢解中的高区域选择性是由于氟-亚基苄基位置处氢解裂解的延迟...
Doi:10.1246/cl.2004.1424

海关参考信息

2902600000-乙苯
2901100000-饱和无环烃
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-6245937-B1
优先权日:1996-11-29
标题 :Liquid phase parallel synthesis of chemical libraries
发明人：CHENG SOAN; SAUNDERS JOHN
权利人:DUPONT PHARMACEUTICALS RES LAB
摘要:This invention features methods of biphasic synthesis for synthesizing combinatorial libraries and combinatorial libraries of chemical compounds utilizing the template, and combinatorial libraries of chemical compounds formed by the methods of this invention.

专利号:US-6608196-B2
优先权日:2001-05-03
标题 :Process for solid supported synthesis of pyruvate-derived compounds
发明人：WANG BING; JANAGANI SATYANARAYANA; CALLAWAY WYETH B; SESSLER JONATHAN L
权利人:GALILEO PHARMACEUTICALS INC
摘要:Provided are processes for synthesizing structurally diverse pyruvate-derived compounds using a parallel approach on a solid phase support. Examples of such a solid phase support include resins which have also been used in solid phase peptide synthesis.

专利号:US-2002048774-A1
优先权日:1996-11-29
标题 :Liquid phase parallel synthesis of chemical libraries

专利号:EP-2300484-B1
优先权日:2008-05-05
标题:Novel class of spiro piperidines for the treatment of neurodegenerative diseases
发明人：BRODNEY MICHAEL AARON; HELAL CHRISTOPHER JOHN; O'NEILL BRIAN THOMAS
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:EP-4116291-A1
优先权日:2020-03-04
标题:Synthesis of novel ep4 antagonist and use in cancers and inflammations

专利号:US-2023125494-A1
优先权日:2020-03-04
标题 :Synthesis of novel ep4 antagonist and use in cancer and inflammation