CAS: 614-21-1; 2-Nitro-1-Phenylethanone

上下游产品

benzoyl cyanide nitromethane iodoacetophenone oxo-phenyl-acetaldehyde oxime3-[2]furyl-2,4-dinitro-1-phenyl-butan-1-one 2,4-dinitro-1-phenyl-3-[2]thienyl-butan-1-one H-pyrimidin-4-one2,6-diamino-5-(2-nitro-1-phenyl-ethylLiDenamino)-3H-pyrimidin-4-one 3-nitro-2-phenylquinoline

📜2-异亚硝基苯乙酮置于氯仿,三氟过氧乙酸体系中,化学反应生成 苯甲酰硝基甲烷
参考文献:Peroxytrifluoroacetic Acid. Vi. The Oxidation Of Oximes To Nitroparaffins1,2
标题:Peroxytrifluoroacetic Acid. Vi. The Oxidation Of Oximes To Nitroparaffins1,2
摘要:
DOI:10.1021/ja01622A036

专利信息

专利号:US-9873689-B2
优先权日:2014-11-07
标题:Synthesis of fatostatin based polycyclic compounds
发明人：CANTRELL JR WILLIAM R
权利人:FGH BIOTECH INC
摘要:The present invention relates to methods and strategies for large-scale synthesis of compounds having the chemical structure: n nThe R substituents are H, methyl, isopropyl, benzyl, cyclohexyl, cyclopropylmethyl, methoxy, tert-butyloxycarbonyl, methanesulfonyl, p-toluenesulfonyl, quinolinesulfonyl, or thiophenesulfonyl groups. The method comprises condensing prothionamide with a halo nitroacetophenone to form a nitrophenyl substituted thiazole, reducing the nitro group to form an amine and derivatizing the amine to produce the compound.

专利号:US-9150497-B2
优先权日:2011-10-14
标题 :Continuous two step flow synthesis of M-amino acetophenone
发明人：KULKARNI AMOL ARVIND; JOSHI RAMESH ANNA; JOSHI ROHINI RAMESH
权利人:COUNCIL SCIENT IND RES
摘要:Disclosed herein is a continuous tubular reactor based conversion of acetophenones to amino substituted acetophenones wherein the nitration is carried out at −10 to 10° C. followed by reduction to m-nitrophenone resulting in uniform output of product, said process comprising the steps of: a) Nitrating acetophenone with nitrating agent (nitration mixture or fuming nitric acid) at −10 to 10° C.; b) Isolating m-nitro acetophenone from a mixture of o and m-nitro acetophenone and c) Reducing the m-nitro to obtain m-amino acetophenone.

专利号:US-4490374-A
优先权日:1982-09-30
标 题:5,6-Dialkoxy-3,4-optionally substituted-2(1H)quinazolinones, composition and method of use
发明人：BANDURCO VICTOR T; LEVINE SEYMOUR D; MULVEY DENNIS M; TOBIA ALFONSO J
权利人:ORTHO PHARMA CORP
摘要:The synthesis of substituted quinazolinones is described. The novel quinazolinones are renal vasodilators and thereby increase renal blood flow, and are useful as cardiovascular agents.

专利号:US-12258318-B2
优先权日:2019-06-17
标题 :Synthesis method for 1-methyl-1H-indazole-6-carboxylic acid
发明人：YANG JUN; Xue Duoqing; WU YONG; CHEN LIHUANG; ZHAI LIANHUA
权利人:ACCELA CHEMBIO CO LTD
摘要:The present application provides a synthesis method for 1-methyl-1H-indazole-6-carboxylic acid. The synthesis method comprises: using 2-fluoro-4-bromobenzaldehyde and methylhydrazine as raw materials to obtain 6-bromo-1-methylindazole by means of an annulation reaction, and then performing a methyl formate reaction and a hydrolysis reaction, so as to obtain the 1-methyl-1H-indazole-6-carboxylic acid. The synthesis method provided in the present application can directly synthesize a 1-position methyl substituted indazole without isomers, thereby avoiding the problem that impurities are difficult to be removed in subsequent separation, thus improving the purity of a product. The yield of the annulation reaction can reach 85%.

专利号:US-7301049-B2
优先权日:2001-06-21
标 题:Photolabile esters and their uses
发明人：SERAFINOWSKI PAWEL JERZY; GARLAND PETER BRYAN
权利人:CANCER RES INST
摘要:Compounds which are capable of generating acid on photolysis are disclosed, and the uses of these compounds, especially for deprotecting the termini of nucleic acid molecules or peptides during synthesis of arrays. The compounds described herein may be employed in the detritylation of 5′-O-dimethoxytrityl (DMT) protected nucleotides by photolysing the compounds to generate an acid capable of removing the DMT group allowing oligonucleotide arrays to be synthesised using readily available 5′-O-DMT-nucleoside-3′-O-phosphoramidite monomers conventionally used in solid phase nucleic acid synthesis. A method of avoiding the effects of stray light in projection lithography techniques is also disclosed.

专利号:US-6177568-B1
优先权日:1995-01-09
标题:Intermediates for the synthesis of camptothecin derivatives