CAS: 42973-56-8; 2-Hydroxy-3-Methoxyphenylacetonitrile

该化合物是一种有机化合物,其特征是附于苯环的氢氧基组(OH)和甲氧基组(OCH3),以及乙酰苯基功能组(-CN),该化合物通常是一种固体或晶体物质,在极有机溶剂中溶解.其分子结构表明,它可能表现出酸性和基本特性,因为可参与氢联结的氢氧基组具有酸性和基本特性.该甲基氧组可影响化合物的再活性和稳定性,经常加强其脂性. 2-Hydroxy-3-metroxybenezeneetonitrele可能在不同领域,包括医药和农用化学剂,因其潜在的生物活动和合成途径的中间用途.与许多有机化合物一样,应参考安全数据,以了解其处理和毒性剖面.

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物理性质

MSDS等安全信息

上下游产品

2-(aminomethyl)-6-methoxyphenol potassium cyanide (7Z)-(1R,3S,4R,5S)-2-(cyanomethylene)-3-hydroxy-4,5-dimethoxycyclohexyl β-D-glucopyranoside sodium cyanide 2-(2-amino-ethyl)-6-methoxy-phenol 1,1-dimethylethyl 4-({[2-(cyanomethyl)-6-(methyloxy)phenyl]oxy}methyl)piperidine-1-carboxylate 5-methoxybenzo[b]thieno[2,3-f]oxepine-9-carbonitrile 7-methoxy-2-phenylbenzo[b]furan

合成工艺路线路线简述

    📜邻香草醛置于sodium Tetrahydroborate体系中,用 甲醇,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 20.17H,反应生成 2-羟基-3-甲氧基苯乙腈
    参考文献:One-Pot Transition-Metal-Free Synthesis Of Dibenzo[b,F]Oxepins From 2-Halobenzaldehydes
    标题:One-Pot Transition-Metal-Free Synthesis Of Dibenzo[b,F]Oxepins From 2-Halobenzaldehydes
    摘要:A One-Pot Transition-Metal-Free,Base-Mediated Synthesis Of Dibenzo[b,F]Oxepins Was Developed. The Reaction Of 2-Halobenzaldehydes With (2-Hydroxyphenyl)Acetonitriles Proceeds Via A Sequential Aldol Condensation And Intramolecular Ether Formation Reaction In The Presence Of Cs2Co3 And Molecular Sieves In Toluene.
    DOI:10.1021/ol302371S

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    主要参考文献

    参考标题:Palladium-Catalyzed Addition Of Potassium Aryltrifluoroborates To Aliphatic Nitriles: Synthesis Of Alkyl Aryl Ketones, Diketone Compounds, And 2-Arylbenzo[B]Furans
    作者:Xingyong Wang,Miaochang Liu,Long Xu,Qingzong Wang,Jiuxi Chen,Jinchang Ding,Huayue Wu |发布日期:2013.6.7
    摘要:Developed, Leading To A Wide Range Of Alkyl Aryl Ketones With Moderate To Excellent Yields. Moreover, Several Dinitriles (E.G., Malononitrile, Glutaronitrile, And Adiponitrile) Were Applicable To This Process For The Construction Of 1,3-, 1,5-, Or 1,6-Dicarbonyl Compounds. The Scope Of The Developed Approach Is Successfully Explored Toward The One-Step Synthesis Of 2-Arylbenzo[b]Furans Via Sequential

    合成参考文献


    参考文献:10.1007/s12010-025-05400-3
    摘要:Rangasamy K, Chandrasekaran V, Kadersulthan M, Murugesan G, Natarajan J. GC-MS Profiling and In Silico Pathway Mapping of Brevibacterium casei VRK 1 Metabolites for exploring Anti-inflammatory and Antioxidant Activities. Appl Biochem Biotechnol. 2025 Nov;197(11):7581–608. doi: 10.1007/s12010-025-05400-3.
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