CAS: 39989-39-4; 7-Methoxyisoquinoline

该化合物是一种有机化合物,其特征是其异丙醇结构,由引信的苯和环组成.在异丙醇框架的7位置上存在一个甲氧基(-OCH3)群体,意义重大,因为它会影响化合物的化学反应和潜在的生物活动.该化合物一般是黄色的黄色到褐色的固体,在乙醇和二甲基硫氧化物等有机溶剂中溶解,但水中的溶性有限.7-甲基氧基线由于其潜在的药理特性,包括抗图象和抗微生物活动,对药化学具有兴趣.其结构允许进行各种化学修改,这些修改可以提高化合物的生物效率或改变其药用皮肤学特性.与许多异丙基物衍生物一样,它也可能表现出荧光性,使它在某些分析应用中有用.应当参考安全数据,用于处理和接触任何化学物质,例如任何化学物质的接触准则.

结构式图片

相似化合物

52986-70-6 90806-58-9 15248-39-2

物理性质

MSDS等安全信息

欧盟法规

C&L通报

上下游产品

N-(3-methoxybenzyl)-N-tosylaminoacetaldehyde dimethyl acetal 2,2-diethoxy-N-(3-methoxybenzyl)ethanamine 2,4,6-Trimethyl-benzenesulfonate2-amino-7-methoxy-isoquinolinium; (2,2-Dimethoxy-ethyl)-[1-(3-methoxy-phenyl)-meth-(Z)-ylidene]-amine N-methyl-7-methoxyisoquinolinium iodide 7-methoxy-1,2,3,4-tetrahydroisoquinoline 7-methoxyisoquinoline 2-oxide 7-methoxy-8-nitro-isoquinoline

合成工艺路线路线简述

    3-Methoxy-N-(2,2-Dimethoxyethyl)Benzylidenamine置于硫酸体系中,化学反应生成 7-甲氧基异喹啉
    参考文献:Discovery Of Novel Tetrahydroisoquinoline Derivatives As Potent And Selective Factor Xa Inhibitors
    标题:Discovery Of Novel Tetrahydroisoquinoline Derivatives As Potent And Selective Factor Xa Inhibitors
    摘要:A Series Of Novel 2,7-Disubstituted Tetrahydroisoquinoline Derivatives Were Designed And Synthesized. Among These Derivatives,Compounds I And 2 (Jtv-803) Exhibited Potent Inhibitory Activity Against Fxa And Good Selectivity With Respect To Other Serine Proteases (Thrombin,Plasmin,And Trypsin). In Addition,Compound 2 Exhibited Potent Anti-Fxa Activity After Intravenous And Oral Administration To Cynomolgus Monkey,And Showed A Dose-Dependent Antithrombotic Effect In A Rat Model Of Venous Thrombosis. (C) 2004 Elsevier Ltd. All Rights Reserved.
    DOI:10.1016/j.Bmcl.2004.10.033

    海关参考信息

    专利信息


    专利号:US-7999090-B2
    优先权日:2000-07-07
    标 题:Fungal cell wall synthesis gene
    发明人：TSUKAHARA KAPPEI; HATA KATSURA; SAGANE KOJI; NAKAMOTO KAZUTAKA; TSUCHIYA MAMIKO; WATANABE NAOAKI; OHBA FUMINORI; TSUKADA ITARU; UEDA NORIHIRO; TANAKA KEIGO; KAI JUNKO
    权利人:EISAI R&D MAN CO LTD
    摘要:The present invention provides isolated DNA encoding a GWT1 protein having activity to confer resistance of a fungus against a compound of formula Ia, and wherein a defect of a function of the GWT1 protein leads to a decrease in the amount of a glycosylphosphatidylinositol (GPI)-anchored protein in the cell wall of a fungus.

    专利号:CN-117800909-A
    优先权日:2023-12-27
    标题:A kind of synthesis method of nitrogen-containing aromatic heterocyclic methylamine

    专利号:MX-2008013487-A
    优先权日:2000-07-07
    标 题 :SYNTHESIS GEN OF THE FUNGAL CELL WALL.

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    主要参考文献

    参考标题:Synthesis Of Indole-Dihydroisoquinoline Sulfonyl Ureas Via Three-Component Reactions
    作者:Stuart Pearson,Shaun Fillery,Kristin Goldberg,Julie Demeritt,Jonathan Eden,Jonathan Finlayson,Anil Patel |发布日期:2018.12
    摘要:Indoles In A 3-Component Reaction To Generate A Library Of Dihydroisoquinoline Derivatives. Using A Differential Protecting Group Strategy, Products Could Be Further Derivatised. Synthesis Of Isoquinoline Starting Materials Using Several Different Methods Is Also Described. Isoquinolines Activated With Sulfamoyl Chlorides Were Reacted With Indoles In A 3-Component Reaction To Generate A Library Of

    合成参考文献


    摘要:Álvarez, M.; Joule, J. A., Science of Synthesis, (2005) 15, 709.
    摘要:Álvarez, M.; Joule, J. A., Science of Synthesis, (2005) 15, 712.
    摘要:Álvarez, M.; Joule, J. A., Science of Synthesis, (2005) 15, 704.
    摘要:Álvarez, M.; Joule, J. A., Science of Synthesis, (2005) 15, 764.
    摘要:Álvarez, M.; Joule, J. A., Science of Synthesis, (2005) 15, 708.
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