CAS: 3438-46-8; 4-Methylpyrimidine

该化合物是一种七环有机化合物,其特征为以一个火利米丁环替换成一个甲基组,其基本性可归因于氮原子,使其参与核分裂性反应.此外,该化合物可能展示生物活动,使其对医药化学感兴趣.安全数据表明,该化合物应谨慎处理,因为它在与皮肤或眼睛接触时可能会引起刺激.

结构式图片

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1558-17-4 14331-54-5 42839-04-3

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CAS号5436-21-5 4,4-二甲氧基-2-丁酮 | CAS号77287-34-4 甲亚胺酸 | CAS号5424-21-5 2,4-二氯-6-甲基嘧啶 | CAS号56745-01-8 5-溴-2,4-二氯-6-甲基嘧啶 | CAS号15018-56-1 5-溴-6-甲基尿嘧啶 | CAS号90210-55-2 6-benzyl-1-oxid... | CAS号13036-57-2 2-氯-4-甲基嘧啶 | CAS号3435-25-4 4-氯-6-甲基嘧啶 | CAS号63170-77-4 2-肼基-4-甲基嘧啶 | CAS号1073-65-0 4-嘧啶甲醛肟 | CAS号185848-10-6 1-(4-甲氧基苯基)-2-(... | CAS号4786-20-3 2-丁烯腈 | CAS号54509-73-8 ethene | CAS号75-05-8 乙腈 | CAS号107-12-0 丙腈 | CAS号31462-59-6 4-嘧啶甲酸 | CAS号2435-50-9 4-嘧啶甲醛

合成工艺路线路线简述

    2,4-二氯-6-甲基嘧啶置于甲醇,Palladium On Activated Charcoal,Magnesium Oxide体系中,化学反应生成 4-甲基嘧啶
    参考文献:Pyrimidine N-Oxides And Their Infrared Absorption Characteristics
    标题:Pyrimidine N-Oxides And Their Infrared Absorption Characteristics
    摘要:
    DOI:10.1021/ja01566A054

    专利信息


    专利号:US-9755163-B2
    优先权日:2010-04-30
    标 题:Synthesis of four coordinated palladium complexes and their applications in light emitting devices thereof
    发明人:LI JIAN; TURNER ERIC
    权利人:ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIV; ARIZONA BOARD OF REGENTS ACTING FOR OR ON BEHALF OF ARIZONA STATE UNIV
    摘要:Synthesis of four coordinated palladium complexes and their applications in light emitting devices thereof.

    专利号:US-9126995-B2
    优先权日:2011-11-08
    标题:Method for catalytic asymmetric synthesis of optically active isoxazoline compound and optically active isoxazoline compound
    发明人:TOYAMA KEN-ICHI; MORIYAMA YUJI; MATOBA KAZUTAKA; YAOSAKA MANABU; IKEDA EITATSU
    权利人:NISSAN CHEMICAL IND LTD
    摘要:There is provided a method for catalytic asymmetric synthesis of optically active isoxazoline compound and an optically active isoxazoline compound. A method for catalytic asymmetric synthesis of optically active isoxazoline compound of a formula (6) including reacting an α,β-unsaturated carbonyl compound of a formula (1) and a hydroxylamine in a solvent in the presence of a base by adding a chiral phase transfer catalyst. An optically active isoxazoline compound of a formula (13) that can be synthesized by the method.

    专利号:US-9324957-B2
    优先权日:2010-04-30
    标 题:Synthesis of four coordinated gold complexes and their applications in light emitting devices thereof
    发明人:LI JIAN; TUMER ERIC
    权利人:LI JIAN; TUMER ERIC; UNIV ARIZONA STATE
    摘要:Synthesis of four coordinated gold complexes and their applications in light emitting devices thereof.

    专利号:WO-2024020091-A1
    优先权日:2022-07-19
    标 题 :Inhibitors of short-chain dehydrogenase activity for reducing glial fibrillary acidic protein levels
    发明人:MARKOWITZ SANFORD; PIEPER ANDREW
    权利人:UNIV CASE WESTERN RESERVE; THE US GOV AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS
    摘要:A method of decreasing blood glial fibrillary acidic protein (GFAP) levels in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor. Astroglia cells are the major and perhaps most abundant cell types in the brain. In healthy brain, astrocytes help with providing structural and network support for neurons and interface with the brain vasculature, including the blood-brain-barrier. Functionally, astrocytes are involved with providing neurotrophic factors (such as glial derived neurotrophic factor (GDNF)), and cytokine/chemokine release that influences the global and local inflammatory response environments, as well as working closely with neurons involved in the glutamate-glutamine synthesis/recycling pathway.

    专利号:US-8138272-B2
    优先权日:2006-05-22
    标 题:Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds
    发明人:KONRADI ANDREI W; SMITH JENIFER L
    权利人:KONRADI ANDREI W; SMITH JENIFER L; ELAN PHARM INC
    摘要:This invention provides an improved synthesis of polymer conjugates of formula (I), n nof agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using “Mitsunobuâ€? or related reaction conditions.

    专利号:US-9698359-B2
    优先权日:2011-05-26
    标 题 :Synthesis of platinum and palladium complexes as narrow-band phosphorescent emitters for full color displays
    发明人:LI JIAN; TURNER ERIC
    权利人:ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIV
    摘要:Platinum and palladium complexes are disclosed that can be useful as narrow band phosphorescent emitters. Also disclosed are methods for preparing and using the platinum and palladium complexes.
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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Gabriella Tamasi, Et Al. [参考文献]: T Ishida, Et Al. Ferromagnetic Exchange Coupling Of Vanadium(Iv) Dpi Spins Across Pyrimidine Rings: Dinuclear Complexes Of Oxovanadium(Iv) Bis(1,1,1,5,5,5-Hexafluoropentane-2,4-Dionate) Bridged By Pyrimidine Derivatives. Inorg Chem. 2001 Dec 31;40(27):7059-64.

    合成参考文献


    摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 134.
    摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 120.
    摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 353.
    摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 334.
    摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 318.
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