CAS: 26673-32-5; 7-Chloro-3,4-Dihydronaphthalen-1(2H)-One

上下游产品

3,4-二氢-1(2H)-萘酮 3,4-Dihydronaphthalene-1(2H)-One 529-34-0
6-氯-1,2,3,4-四氢萘 6-Chloro-1,2,3,4-Tetrahydronaphthalene 35337-44-1
7-氨基-1-四氢萘酮 7-Amino-1-Tetralone 22009-40-1
4-(3-氯苯基)-4-氧代丁酸 4-(3-Chlorophenyl)-4-Oxobutyric Acid 62903-14-4
7-硝基-3,4-二氢-2H-1-萘酮 7-Nitro-3,4-Dihydro-2H-Naphthalen-1-One 40353-34-2

📜3-(4-氯苯甲酰)丙酸置于一水合肼,Potassium Hydroxide体系中,用 乙二醇 用作溶剂,化学反应 2.33H,反应生成7-氯-3,4-二氢-2H-1-萘酮
参考文献:Schmidt反应和beckmann重排在双环内酰胺合成中的应用:一些机理上的考虑
标题:Schmidt反应和beckmann重排在双环内酰胺合成中的应用:一些机理上的考虑
摘要:据报道,使用两个不同的条件进行适当酮的施密特反应,并使用两个不同的条件进行相应酮肟的贝克曼重排,合成了一些类型3和4的甲氧基取代的双环内酰胺.通过反应的高效液相色谱分析来确定反应的烷基与芳基的迁移比.讨论了所报告反应的机制,确定了所报告机制的某些局限性,并根据各种反应的结果提出了另一种机制.施密特反应和贝克曼重排反应的应用被用于合成一些3型和3型氯双环内酰胺.4.
Doi:10.1071/ch09402

专利信息

专利号:US-2023002426-A1
优先权日:2019-11-15
标题 :Chiral synthesis of a tertiary alcohol

专利号:US-5405872-A
优先权日:1990-09-22
标 题 :Anti-hypertensive tetralins
发明人：MCDERMED JOHN D; HURLEY KEVIN P; CHANG VINCENT H; TADEPALLI ANJANEYULU S
权利人:BURROUGHS WELLCOME CO
摘要:PCT No. PCT/GB91/01602 Sec. 371 Date Mar. 22, 1993 Sec. 102(e) Date Mar. 22, 1993 PCT Filed Sep. 19, 1991 PCT Pub. No. WO92/05143 PCT Pub. Date Apr. 2, 1992.This invention relates to tetralin derivatives useful in medicine for the treatment of hypertension, to the synthesis of the compounds, to the pharmaceutical formulations containing the compounds and the use of the compounds in medical practice.

专利号:WO-2021097139-A1
优先权日:2019-11-15
标 题 :Chiral synthesis of a tertiary alcohol

专利号:WO-2023230649-A1
优先权日:2022-05-30
标题:Compounds
发明人：BANISTER SAMUEL; JORGENSEN WILLIAM; TAN JINLONG; WHISH LACHLAN
权利人:Psylo Pty Ltd
摘要:The present disclosure relates to compounds of formula (I), their methods of synthesis, and their use in the treatment of mental illness or central nervous system disorders.