CAS: 15717-17-6; 2-Chlorobenzothioamide

相似化合物

2521-24-6 1918-13-4 2775-38-4

上下游产品

CAS号609-66-5 2-氯苄胺 | CAS号873-32-5 邻氯苯腈 | CAS号3717-28-0 邻氯苯甲醛肟 | CAS号298-06-6 二硫代磷酸二乙酯 | CAS号118-91-2 邻氯苯甲酸 | CAS号609-65-4 邻氯苯甲酰氯 | CAS号89-98-5 邻氯苯甲醛 | CAS号121-44-8 三乙胺 | CAS号50907-46-5 5-(2-氯苯)-1H-四唑 | CAS号944275-21-2 2-(2-氯苯基)噻唑-4-羧酸 | CAS号873-32-5 邻氯苯腈 | CAS号132089-36-2 2-(2-氯苯基)-噻唑-4-羧酸乙酯 | CAS号23821-79-6 2-[2-(2-氯苯基)-4-... | CAS号61033-69-0 2-(2-氯苯基)-4,5-二... | CAS号639517-84-3 2-(2-氯苯基)-噻唑-4-甲醛 | CAS号639517-86-5 [2-(2-氯苯基)噻唑-4-基]甲醇

📜在 水体系中,化学反应生成2-氯硫代苯甲酰胺
参考文献:在水性介质中无金属,一锅法将醛氧化转化为伯硫代酰胺
标题:在水性介质中无金属,一锅法将醛氧化转化为伯硫代酰胺
摘要:摘要 多种醛与氨水,分子碘和 O,O-二乙基二硫代磷酸的一锅串联反应容易得到相应的伯硫代酰胺.这是一种廉价,实用且无金属的方法,可以在水性介质中从醛中获取各种硫代酰胺.简单地通过过滤然后用硫代硫酸钠水溶液和水连续洗涤来获得纯产物.[本文提供补充材料.访问出版商的 Synthetic Communications® 在线版,获取以下免费补充资源:完整的实验和光谱细节.] 图形摘要
Doi:10.1080/00397911.2013.808350

专利信息

专利号:US-8552175-B2
优先权日:2009-04-23
标题:Sulfur transfer reagents for oligonucleotide synthesis
发明人：GUZAEV ANDREI P
权利人:GUZAEV ANDREI P; A M CHEMICALS INC
摘要:The use of N-formamidino-5-amino-3H-1,2,4-dithiazole-3-thiones, 5-phenyl-3H-1,2,4-dithiazole-3-thiones, and derivatives thereof as novel, efficient sulfur-transfer reagents is disclosed. Sulfur transfer from these reagents to compounds containing a P(III) atom (e.g., triphenylphosphine, 5′-O-DMT-thymidine 2-cyanoethyl-(N,N-diisopropyl)phosphoramidite, and 5′-O-DMT-3′-O-levulinyl dithymidilyl 2-cyanoethyl phosphite), was studied in solution by 31 P NMR and HPLC. The sulfur transfer from title compounds was also studied in the solid-phase synthesis of oligonucleotide phosphorothioates by phosphoramidite methods. In this application, the efficiency of the sulfur transfer reaction for 2′-deoxyoligonucleotides was better than 99.5%. The novel sulfurizing agents are synthesized, at low cost, using simple chemical methods. As opposed to many sulfur transfer reagents known in the prior art such as 1,2-benzodithiol-3-one-1,1-dioxide (Beaucage reagent) and 5-ethoxy-3H-1,2,4-dithiazole-2-one (EDIT), the sulfurizing agents disclosed herein are highly stable in solution, which increases their practical and commercial value.

专利号:CN-107954908-B
优先权日:2017-12-10
标 题:Under a kind of microwave radiation in water phase benzene thiocarbamide catalytic synthesis of diaryl thioether method

专利号:CN-107954908-A
优先权日:2017-12-10
标题:A kind of method that phenylthiourea catalyzes the synthesis of diaryl sulfide in aqueous phase under microwave radiation

专利号:US-2016229847-A1
优先权日:2013-10-04
标 题:Novel bicyclic pyridinones as gamma-secretase modulators
发明人：PETTERSSON MARTIN YOUNGJIN; AM ENDE CHRISTOPHER WILLIAM; GREEN MICHAEL ERIC; JOHNSON DOUGLAS SCOTT; KAUFFMAN GREGORY WAYNE; O'DONNELL CHRISTOPHER WILLIAM; PATEL NANDINI CHATURBHAI; STEPAN ANTONIA FRIEDERIKE; STIFF CORY MICHAEL; SUBRAMANYAM CHAKRAPANI; TRAN TUAN PHONG; VERHOEST PATRICK ROBERT
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula II as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.