CAS: 113378-31-7; Semduramicin
该化合物是一种化学化合物,主要用于兽医,特别是家禽生产,主要用于兽医,属于聚醚抗生素类,以其能够将离子迁移到细胞膜间,能够影响细胞过程和提高牲畜饲料效率而闻名.Semduramicin展示抗微生物特性,特别是针对某些模范抗菌细菌和共生动物的抗微生物特性,使其有效地预防和治疗鸡体内的孔虫病.该化合物通常通过饲料施用,其特点是对哺乳动物的毒性较低,允许其在食物生产动物中使用.其行动机制包括干扰目标生物体内的离子保持,导致细胞死亡.与许多兽医药物一样,对红丁胺因的使用进行管制,并对动物产品中的残留物进行监测以确保食品安全.总的来说,Semduramicin在提高农业环境中动物健康和生产力方面发挥着重要作用.
- 英文名称Semduramicin
- 中文名称生度米星
- IUPAC名称2-((2R,3S,4S,5R,6S)-2,4-dihydroxy-6-((R)-1-((2S,5S,7S,8R,9R)-9-hydroxy-2-((2R,2'R,3'S,5R,5'R)-5'-((2S,3S,5R,6S)-6-hydroxy-3,5,6-trimethyltetrahydro-2H-pyran-2-yl)-3'-(((2S,5S,6R)-5-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-methyloctahydro-[2,2'-bifuran]-5-yl)-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl)ethyl)-5-methoxy-3-methyltetrahydro-2H-pyran-2-yl)acetic acid
- 其它别名Semduramicin; Semduramycin; 2H-Pyran-2-acetic acid, tetrahydro-2,4-dihydroxy-6-(1R)-1-(2S,5R,7S,8R,9S)-9-hydroxy-2,8-dimethyl-2-(2S,2R,3S,5R,5R)-°Ctahydro-2-methyl-5-(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl-3-(2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-
- CAS编号113378-31-7
- MFCD编号:MFCD00867206
- FDA UNII编号:P6VXL377WL
- 分子式:C45H76O16分子量:873.079
- 产品CID: 164020
- 同类组份化合物CAS119068-77-8 (sodium)113378-31-7 (free acid)
- 产品分类有机原料 → 有机氧化合物
物理性质
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2905122000-异丙醇
2905143000-叔丁醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.
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品牌试剂参考报价(招募中)
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主要参考文献
1: EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP); Bampidis V, Azimonti G, Bastos ML, Christensen H, Durjava M, Dusemund B, Kouba M, López-Alonso M, López Puente S, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F, Villa RE, Woutersen R, Teodorovic I, Tarres JC, Vettori MV. Safety for the environment of a feed additive consisting of semduramicin sodium (Aviax 5%) for chickens for fattening (Phibro Animal Health s.a.). EFSA J. 2023 Dec 6;21(12):e8467. doi: 10.2903/j.efsa.2023.8467.
2: EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP); Bampidis V, Azimonti G, Bastos ML, Christensen H, Dusemund B, Durjava M, Kouba M, López-Alonso M, López Puente S, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F, Villa RE, Woutersen R, Maradona MP, Alija-Novo N, Anguita M, Innocenti ML, Pettenati E, Revez J, Brozzi R. Safety and efficacy of a feed additive consisting of Weizmannia faecalis DSM 32016 (TechnoSpore50®) for poultry for fattening, poultry reared for laying/breeding, ornamental birds and suckling and weaned Suidae piglets (Biochem Zusatzstoffe Handels- und Produktionsgesellschaft GmbH). EFSA J. 2023 Nov 3;21(11):e08355. doi: 10.2903/j.efsa.2023.8355.
3: EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP); Bampidis V, Azimonti G, Bastos ML, Christensen H, Dusemund B, Fašmon Durjava M, Kouba M, López-Alonso M, López Puente S, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F, Sanz Y, Villa RE, Woutersen R, Bories G, Cocconcelli PS, Finizio A, Gropp J, Rychen G, Teodorovic I, Brozzi R, Holczknecht O, Pettenati E, Revez J, Vettori MV. Safety of a feed additive consisting of semduramicin sodium (Aviax 5%) for chickens for fattening (Phibro Animal Health s.a.). EFSA J. 2022 Aug 1;20(8):e07432. doi: 10.2903/j.efsa.2022.7432.
合成参考文献
参考文献:10.1016/j.vetpar.2003.12.009
摘要:Li GQ, Kanu S, Xiang FY, Xiao SM, Zhang L, Chen HW, Ye HJ. Isolation and selection of ionophore-tolerant Eimeria precocious lines: E. tenella, E. maxima and E. acervulina. Vet Parasitol. 2004 Feb 06;119(4):261–76. doi: 10.1016/j.vetpar.2003.12.009.
参考文献:10.1080/19440049.2014.927593
摘要:Olejnik M, Szprengier-Juszkiewicz T, Jedziniak P. Distribution of semduramicin in hen eggs and tissues after administration of cross-contaminated feed. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2014;31(8):1393–8. doi: 10.1080/19440049.2014.927593.
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