CAS: 105-59-9; N-Methyldiethanolamine

该化合物是被归类为alkanolami的有机化合物,其特征是其有矿功能组,附于两个乙醇胺糖和甲基组,具有基本和核生殖特性,在各种化学应用中有用.N-甲基乙醇胺一般是无色的,可粉黄液,有温和的amine味.它具有血色,可以吸收空气中的水分,在水和许多有机溶剂中溶解.该化合物经常被用于生产表面活性剂,腐蚀抑制剂,并作为合成其他化学品的建筑块.此外,该化合物在个人护理产品的配制和纺织工业中也具有应用性.由于其矿性,它也可以参与诸如碱性与相互交融等反应,从而在有机合成中具有灵敏性.在处理该化合物时,必须采取安全防范措施,因为它会刺激皮肤和眼睛.

结构式图片

欧盟法规

统一分类与标签REACH注册ECHA物质工作场所安全标识要求ECHA物质C&L通报CoRAP评估清单REACH预注册

上下游产品

CAS号75-21-8 环氧乙烷 | CAS号74-89-5 氨基甲烷 | CAS号109-83-1 2-甲胺乙醇 | CAS号111-44-4 二氯乙基醚 | CAS号50-00-0 甲醛 | CAS号102-71-6 三乙醇胺 | CAS号107-07-3 2-氯乙醇 | CAS号55-86-7 盐酸氮芥 | CAS号65796-77-2 苯硼酸苯硼酸N-甲基二乙醇胺酯 | CAS号20073-50-1 2-(恶唑烷-3-基)乙醇 | CAS号50-00-0 甲醛 | CAS号74-89-5 氨基甲烷 | CAS号4097-88-5 2,2'-二氨基-N-甲基二乙胺 | CAS号5753-50-4 2-[(2-氨基乙基)甲基氨基]乙醇 | CAS号55-86-7 盐酸氮芥 | CAS号3074-43-9 1-甲基-4-苯基哌嗪 | CAS号382-28-5 全氟(N-甲基吗啉) | CAS号250688-32-5 Perfluoro-[N,N-... | CAS号51-75-2 氮芥

合成工艺路线路线简述

    Ethoxy-Bis(2-Hydroxyethyl)Methylammonium 反应生成N-甲基二乙醇胺
    参考文献:Torigoe,M.,Chemical And Pharmaceutical Bulletin,1961,Vol. 9,P. 613-618
    标题:Torigoe,M.,Chemical And Pharmaceutical Bulletin,1961,Vol. 9,P. 613-618

    专利信息


    专利号:US-7247287-B2
    优先权日:2003-06-11
    标 题 :Synthesis of aluminophosphates and silicoaluminophosphates
    发明人:CAO GUANG; SHAH MATU J
    权利人:EXXONMOBIL CHEM PATENTS INC
    摘要:The invention is directed to a method of synthesising silicoaluminophosphate and aluminophosphate molecular sieves using synthesis templates that contain at least one template of general formula R 1 R 2 N—R 3 , wherein R 1 and R 2 are independently selected from the group consisting of alkyl groups having from 1 to 3 carbon atoms and hydroxyalkyl groups having from 1 to 3 carbon atoms; R 3 is selected from the group consisting of 4- to 8-membered cycloalkyl groups, optionally substituted by 1 to 3 alkyl groups having from 1 to 3 carbon atoms, and 4- to 8-membered heterocyclic groups having from 1 to 3 heteroatoms, said heterocyclic groups being optionally substituted by 1 to 3 alkyl groups having from 1 to 3 carbon atoms and the heteroatoms in said heterocyclic groups being selected from the group consisting of O, N, and S. In particular, the present invention relates to the synthesis of silicoaluminophosphate molecular sieves of the CHA framework type having a low silicon to aluminium atomic ratio.

    专利号:US-6835363-B1
    优先权日:2003-08-06
    标题:Synthesis of molecular sieves of CHA framework type
    发明人:STROHMAIER KARL G
    权利人:EXXONMOBIL CHEM PATENTS INC
    摘要:The invention is directed to a method of synthesizing aluminophosphate and silicoaluminophosphate molecular sieves and in particular to the synthesis of aluminophosphate and silicoaluminophosphate molecular sieves using the synthesis templates that contain two dimethylamino moieties in combination with hydrogen fluoride. The use of this template in combination with hydrogen fluoride results in good quality SAPO molecular sieves of CHA framework type with low levels of silicon that are produced in relatively short crystallization times.

    专利号:US-6620983-B1
    优先权日:2002-06-12
    标 题 :Synthesis of aluminophosphates and silicoaluminophosphates
    发明人:CAO GUANG; SHAH MATU J; STROHMAIER KARL G; HALL RICHARD B
    权利人:EXXONMOBIL CHEM PATENTS INC
    摘要:The invention is directed to a method of synthesizing aluminophosphate or silicoaluminophosphate molecular sieves and in particular to the synthesis of silicoaluminophosphate molecular sieves using synthesis templates in combination with a source of fluoride comprising at least two fluoride substituents. The use of such fluorine containing compounds results in good quality low silica SAPO molecular sieves of CHA framework type.

    专利号:WO-2025136243-A1
    优先权日:2023-12-20
    标题:Mechanochemical synthesis of histamine h1-receptor antagonists
    发明人:AYDONAT SIMAY; OZEL MERTCAN; YIGITBASI JOANNA MARIANNA; BAYTEKIN BILGE; COLACINO EVELINA
    权利人:IHSAN DOGRAMACI BILKENT UNIV; CENTRE NAT RECH SCIENT
    摘要:The present invention relates to mechanochemical synthesis of histamine antagonists which are benzhydryl ethers and unsymmetrically disubstitutes piperazines and salts thereof. Said antihistamine active pharmaceutical ingredients can be diphenhydramine hydrochloride, cyclizine hydrochloride and diphenylpyraline hydrochloride. These antihistamines are used in the treatment of allergies, hives, hay fever (allergic rhinitis), conjunctivitis, reactions to insect bites and sings, nausea, motion sickness, insomnia.

    专利号:US-8048402-B2
    优先权日:2005-08-18
    标题:Synthesis of molecular sieves having the chabazite framework type and their use in the conversion of oxygenates to olefins
    发明人:CAO GUANG; SHAH MATU J
    权利人:EXXONMOBIL CHEM PATENTS INC
    摘要:The synthesis of a crystalline aluminophosphate or silicoaluminophosphate molecular sieve having a chabazite-type framework type is conducted in the presence of an organic directing agent having the formula (I)n n[R 1 R 2 R 3 N—R 4 ] + X −   (I)n nwherein R 1 , R 2 and R 3 are independently selected from the group consisting of alkyl groups having from 1 to 3 carbon atoms and hydroxyalkyl groups having from 1 to 3 carbon atoms; R 4 is selected from the group consisting of 4- to 8-membered cycloalkyl groups, optionally substituted by 1 to 3 alkyl groups having from 1 to 3 carbon atoms; 4- to 8-membered heterocyclic groups having from 1 to 3 heteroatoms, said heterocyclic groups being optionally substituted by 1 to 3 alkyl groups having from 1 to 3 carbon atoms and the heteroatoms in said heterocyclic groups being selected from the group consisting of O, N, and S; and aromatic groups optionally substituted by 1 to 3 alkyl groups, said alkyl groups having from 1 to 3 carbon atoms; and X − is an anion.

    专利号:US-4472568-A
    优先权日:1981-11-12
    标 题:Process for the preparation of polyamines from N-monoaryl-N',N'-dialkyl urea compounds and their use for the synthesis of polyurethanes
    发明人:RASSHOFER WERNER; GROEGLER GERHARD
    权利人:BAYER AG
    摘要:This invention relates to an improved process for the preparation of aromatic polyamines containing urethane and/or biuret and/or urea and/or isocyanurate groups and preferably also ether groups by the hydrolysis of poly-N-monoaryl-N',N'-dialkyl urea compounds (1-aryl-3,3-dialkyl ureas). The ureas are obtained by the reaction of secondary aliphatic, cycloaliphatic or saturated heterocyclic amines with divalent to tetravalent isocyanate compounds containing isocyanate end groups attached to aromatic residues. The ureas correspond to the general formula: wherein R1, R2 denote alkyl or cycloalkyl groups, or together form a ring and A denotes a divalent to tetravalent residue attached to the ureas by aromatic groups. Hydrolysis is carried out in the presence of water and up to two equivalents of a base containing hydroxide ions and/or up to two equivalents of a compound containing tertiary amino groups, optionally in the presence of solvents. The use of the polyamines obtained by this process for the synthesis of polyurethanes is also described.
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    合成参考文献


    摘要:Ye, Z.-S., Science of Synthesis Knowledge Updates, (2021) 2, 338.
    摘要:US EPA; Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). Ethanol, 2,2'-(methylimino)bis- (105-59-9). Available from, as of November 7, 2008:
    摘要:Franke C et al; Chemosphere 29: 1501-14 (1994)
    摘要:Currance, P.L. Clements, B., Bronstein, A.C. (Eds).; Emergency Care For Hazardous Materials Exposure. 3rd revised edition, Elsevier Mosby, St. Louis, MO 2007, p. 194
    摘要:Larranaga, M.D., Lewis, R.J. Sr., Lewis, R.A.; Hawley's Condensed Chemical Dictionary 16th Edition. John Wiley & Sons, Inc. Hoboken, NJ 2016., p. 903
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