496-11-7 = 496-11-7 反应条件:1.1 Reagents: Iron,Bromine Solvents: Hexane2.1 Reagents: Butyllithium Solvents: Diethyl Ether2.2 - 标题:The Intermediate Formation Of [4]Metacyclophane On Flash Vacuum Thermolysis 作者:Kostermans,Gerardus B. M.; Et Al 参考文献:Journal Of Organic Chemistry 日期:1988 卷标:53(19) 页码:4531-4]
= 496-11-7 + 876-02-8 + 90-00-6 + 93-51-6 + 581-42-0 + 39151-19-4 + 6443-69-2 + 90-05-1 + 767-59-9 反应条件:1.1 250 H 标题:Catalytic Pyrolysis Of Lignin Over Hierarchical Hzsm 5 Zeolites Prepared By Post-Treatment With Alkaline Solutions 作者:Tang,Songshan; Et Al 参考文献:Journal Of Analytical And Applied Pyrolysis 日期:2019 卷标:137 页码:86-95]
= 496-11-7 + 141-93-5 + 629-50-5 + 99-62-7 + 17171-71-0 + 1074-92-6 反应条件:1.1 Catalysts: Zinc; 6 H,1 Bar,420 °C 标题:Renewable P-Xylene Production By Catalytic Conversion Of Crude Bioglycerol (Gta-Px Process) 作者:Singh,Vijendra; Arumugam,Selvamani; Kumar,Mahesh; Tathod,Anup Prakash; Viswanadham,Nagabhatla 参考文献:Industrial & Engineering Chemistry Research 日期:2023 卷标:62(4) 页码:1788-1796]
= 496-11-7 + 581-42-0 + 3877-19-8 反应条件:1.1 Reagents: Hydrogen Solvents: Tetralin; 3 H,1 Atm,450 °C 标题:Catalytic Cracking Of Low-Density Polyethylene Dissolved In Various Solvents: Product Distribution And Coking Behavior 作者:Machhi,Dharmesh J.; Et Al 参考文献:Journal Of Material Cycles And Waste Management 日期:2023 卷标:25(5) 页码:3005-3020]
= 496-11-7 + 90-00-6 + 581-42-0 + 575-37-1 + 17059-52-8 + 527-53-7 反应条件:1.1 500 °C 标题:Acetic Acid Conversion Reactions On Basic And Acidic Catalysts Under Biomass Fast Pyrolysis Conditions 作者:Psarras,A. C.; Michailof,C. M.; Iliopoulou,E. F.; Kalogiannis,K. G.; Lappas,A. A.; Et Al 参考文献:Molecular Catalysis 日期:2019 卷标:465 页码:33-42]
6134-53-8 = 496-11-7 反应条件:1.1 Reagents: Butyllithium Solvents: Diethyl Ether1.2 - 标题:The Intermediate Formation Of [4]Metacyclophane On Flash Vacuum Thermolysis 作者:Kostermans,Gerardus B. M.; Et Al 参考文献:Journal Of Organic Chemistry 日期:1988 卷标:53(19) 页码:4531-4]
= 496-11-7 + 629-62-9 + 575-37-1 反应条件:1.1 Catalysts: Iron,Calcium; 15 Min,500 °C 标题:Preparation Of Sodium Silicate/red Mud-Based Zsm-5 With Glucose As A Second Template For Catalytic Cracking Of Waste Plastics Into Useful Chemicals 作者:Wang,Xiaofeng; Et Al 参考文献:Rsc Advances 日期:2022 卷标:12(34) 页码:22161-22174
正丙基苯置于platinum On Activated Charcoal体系中,化学反应生成 茚满 参考文献:Liberman Et Al.,Izvestiya Akademii Nauk Sssr,Seriya Khimicheskaya,1959,P. 879,883; Engl. Ausg. S. 846,850 标题:Liberman Et Al.,Izvestiya Akademii Nauk Sssr,Seriya Khimicheskaya,1959,P. 879,883; Engl. Ausg. S. 846,850
专利号:US-9446995-B2 优先权日:2012-05-21 标 题:Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions 发明人:CHONG HYUN-SOON 权利人:CHONG HYUN-SOON; ILLINOIS INST OF TECH 摘要:Stereoselective and regioselective synthesis of compounds via nucleophilic ring opening reactions of aziridinium ions for use in stereoselective and regioselective synthesis of therapeutic and diagnostic compounds.
专利号:US-10189803-B2 优先权日:2008-02-22 标题 :Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions 发明人:CHONG HYUN-SOON 权利人:CHONG HYUN SOON; ILLINOIS INSTITUTE OF TECH 摘要:Stereoselective and regioselective synthesis of compounds via nucleophilic ring opening reactions of aziridinium ions for use in stereoselective and regioselective synthesis of therapeutic and diagnostic compounds.
专利号:US-9353057-B2 优先权日:2003-12-30 标 题:Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof 发明人:GALLOP MARK A; DAI XUEDONG; SCHEUERMAN RANDALL A; RAILLARD STEPHEN P; MANTHATI SURESH K; YAO FENMEI; PHAN THU; LUDWIKOW MARIA; PENG GE; BHAT SEEMA 权利人:XENOPORT INC 摘要:Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.
专利号:US-2013267680-A1 优先权日:2010-09-15 标题:Total chemical synthesis of ubiquitin, ubiquitin mutants and derivatives thereof 发明人:OVAA HUIB; EL OUALID FARID; MERKX REMCO NICOLAAS SEBASTIAAN MICHEL 权利人:OVAA HUIB; EL OUALID FARID; MERKX REMCO NICOLAAS SEBASTIAAN MICHEL; STICHTING HET NL KANKERINST 摘要:The present invention relates to the field of total chemical synthesis of ubiquitin and related peptides. More in particular, a method is provided of solid phase synthesis of ubiquitin, ubiquitin mutants and derivatives thereof. It was the object of the present invention to provide an approach for the total chemical synthesis of ubuiqitin, which allows for the chemical synthesis of virtually any Ub mutant and giving high overall efficiency and purity. The present inventors have surprisingly found that this object can be realized with a method relying on incorporation of special amino acid building blocks. This approach was found to allow for exceptionally high yields of up to 14% and to provide an synthetic entry into virtually any ubiquitin derivative.
专利号:US-2012165520-A1 优先权日:2010-12-23 标题:Process for the synthesis of prodrugs of opioids 发明人:MCGEE PAUL; GARNETT IAN; JUAN E; MANAGE A; CARNIAUX JEAN-FRANCOIS 权利人:MCGEE PAUL; GARNETT IAN; JUAN E; MANAGE A; CARNIAUX JEAN-FRANCOIS 摘要:The present invention provides a process for the synthesis of opioid prodrugs. In particular, the present invention provides a process for the synthesis of opioid prodrugs comprising: treating an opioid, in the form of a salt or a freebase, with a carbonyl synthon to form an activated intermediate and subsequently reacting the activated intermediate with an amine, in the form of a salt or a freebase.
专利号:WO-2024012791-A1 优先权日:2022-07-11 标题 :Electrochemical synthesis of pyrazolines and pyrazoles 发明人:BÄR ROBIN MAXIMILIAN; FORD MARK JAMES; KALDAS SHERIF JAMES; WALDVOGEL SIEGFRIED; HOFMANN SILJA; LINDEN MARTIN 权利人:BAYER AG 摘要:The present invention relates to an electrochemical process for the synthesis of pyrazolines and pyrazoles of formula (I). The process can be especially used for the synthesis of the herbicide safener mefenpyr-diethyl.
[参考文献]: Christopher S Frampton, Et Al. (1S)-1-Phenylethanaminium 4-{[参考文献]: D T Gibson, Et Al. Desaturation, Dioxygenation, And Monooxygenation Reactions Catalyzed By Naphthalene Dioxygenase From Pseudomonas Sp. Strain 9816-4. J Bacteriol. 1995 May;177(10):2615-21. [参考文献]: Dockyu Kim, Et Al. Aromatic Hydroxylation Of Indan By O-Xylene-Degrading Rhodococcus Sp. Strain Dk17. Appl Environ Microbiol. 2010 Jan;76(1):375-7. [参考文献]: G Bieniek, Et Al. Simultaneous Determination Of Ethylbenzene, Indan, Indene And Acenaphthene In Air By Capillary Gas Chromatography. J Chromatogr A. 2000 Sep 8;891(2):361-5. [参考文献]: Janice L Hyatt, Et Al. Selective Inhibition Of Carboxylesterases By Isatins, Indole-2,3-Diones. J Med Chem. 2007 Apr 19;50(8):1876-85.