CAS: 446-22-0; 1-(2-Fluorophenyl)Propan-1-One

上下游产品

CAS号156022-15-0 1-(2-氟苯基)丙醇 | CAS号133745-75-2 N-氟代双苯磺酰胺 | CAS号93-55-0 苯丙酮 | CAS号4111-54-0 二异丙胺基锂 | CAS号58824-51-4 1-(2-fluorophen... | CAS号446-52-6 邻氟苯甲醛 | CAS号394-47-8 2-氟苯甲腈 | CAS号445-28-3 2-氟苯甲酰胺 | CAS号394-35-4 邻氟苯甲酸甲酯 | CAS号1168139-44-3 (R)-1-(2-氟苯基)-1... | CAS号4498-71-9 3-乙基-1H-吲唑

2-氟苯甲酰胺置于ethyl Magnesium Iodide,氯化亚砜,乙醚体系中,化学反应生成 2-氟苯丙酮
参考文献:Borsche; Wagner-Roemmich,Justus Liebigs Annalen Der Chemie,1941,Vol. 546,P. 273,275
标题:Borsche; Wagner-Roemmich,Justus Liebigs Annalen Der Chemie,1941,Vol. 546,P. 273,275

专利信息

专利号:US-8981092-B2
优先权日:2008-09-19
标题 :Substituted 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-ones as modulators of protein kinase activity
发明人：MIRIZZI DANILO; CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; FERGUSON RON; CASUSCELLI FRANCESCO
权利人:MIRIZZI DANILO; CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; FERGUSON RON; CASUSCELLI FRANCESCO; NERVIANO MEDICAL SCIENCES SRL
摘要:Compounds which are 4,7-disubstituted derivatives of 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one compounds, n nor pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, viral infection, prevention of AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmune and neurodegenerative disorders; also disclosed is a process under Solid Phase Synthesis conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.

专利号:CN-103757061-A
优先权日:2014-01-10
标 题 :A method for the synthesis of chiral alcohols using microalgae asymmetric reduction

专利号:EP-1370553-B1
优先权日:2001-03-23
标 题 :Rho-kinase inhibitors
发明人：NAGARATHNAM DHANAPALAN; ASGARI DAVOUD; SHAO JIANXING; LIU XIAO-GAO; KHIRE UDAY; WANG CHUNGUANG; HART BARRY; BOYER STEPHEN; WEBER OLAF; LYNCH MARK; BANKSTON DONALD
权利人:BAYER AG
摘要:Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.