CAS: 39994-75-7; (2S,3R)-Methyl 2-Amino-3-Hydroxybutanoate Hydrochloride

该化合物是氨酸乙酸乙酸盐的一种受保护衍生物,通常用于丙酸合成.甲基酯组增加了有机溶剂中的溶性,而盐盐则提高了稳定性和处理能力.该化合物是固相和溶解阶段的peptide化学的一个多用途建筑块,能够有效地将血清九残留物纳入降低种族化的风险.其高纯度和连续的再活性使它适合研究和工业应用,特别是在制药和生物化学研究中.盐化形式确保了在标准条件下直接储存和延长储存期.

结构式图片

相似化合物

60538-15-0 79617-27-9 24830-94-2

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CAS号67-56-1 甲醇 | CAS号72-19-5 L-苏氨酸 | CAS号60538-19-4 N-b°C-L-threoni... | CAS号24830-94-2 D-别苏氨酸 | CAS号72-19-5 L-苏氨酸 | CAS号82679-55-8 Z-threonine met... | CAS号49705-99-9 (2S,3R)-2-氨基-3-羟基丁酰胺 | CAS号79893-89-3 N-苯甲酰-L-苏氨酸甲酯 | CAS号60538-19-4 N-b°C-L-threoni... | CAS号22325-27-5 4,6-二甲基-2-巯基嘧啶 | CAS号57224-63-2 Z-L-苏氨酸甲酯 | CAS号149198-47-0 (3R,4S)-3-(三乙基硅... | CAS号368424-95-7 4-Oxazolidineca... | CAS号69568-63-4 B°C-L-苏氨酸酰肼

合成工艺路线路线简述

    Boc-苏氨酸甲酯置于盐酸体系中,用 1,4-二氧六环 作为反应溶剂,化学反应生成 L-苏氨酸甲酯盐酸盐
    参考文献: Cdk2 Inhibitors And Methods Of Using The Same[fr] Inhibiteurs De Cdk2 Et Leurs Procédés D'Utilisation
    标题: Cdk2 Inhibitors And Methods Of Using The Same[fr] Inhibiteurs De Cdk2 Et Leurs Procédés D'Utilisation
    摘要:本公开提供了抑制cdk2的化合物,其组合物以及使用它们治疗cdk2相关疾病和疾病的方法.

    海关参考信息

    专利信息


    专利号:US-6495693-B2
    优先权日:1996-11-22
    标题:N-(aryl/heteroaryl) amino acid derivatives, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
    发明人:AUDIA JAMES E; FOLMER BEVERLY K; JOHN VARGHESE; LATIMER LEE H; NISSEN JEFFREY S; PORTER WARREN J; THORSETT EUGENE D; WU JING
    权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI
    摘要:Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

    专利号:US-7026114-B1
    优先权日:1995-09-13
    标 题:Methods and compositions for monitoring polymer array synthesis
    发明人:BARONE ANTHONY D; MC GALL GLENN H; CHAI EVELYN; NGO NAM QUOC
    权利人:AFFYMETRIX INC
    摘要:VLSIPSâ„¢ manufacturing processes are of increasing commercial importance. The present invention provides methods and compositions for monitoring the efficiency and quality of polymer synthesis in VLSIPSâ„¢ arrays. Methods for monitoring polymer synthesis in an array on a substrate are provided. Monoisomeric labels for the labeling of synthetic polymer arrays are provided. Methods and compositions for post-synthetically labeling polymers in polymer arrays are also provided.

    专利号:EP-0525589-A1
    优先权日:1991-07-31
    标题:Asymmetric synthesis of taxol side chain

    专利号:CA-2071160-A1
    优先权日:1991-07-31
    标 题:Asymmetric synthesis of taxol side chain

    专利号:US-2010063150-A1
    优先权日:2005-06-23
    标题 :Aflatoxin Production Inhibitor and Method for Controlling Aflatoxin Contamination Using the Same
    发明人:SAKUDA SHOHEI
    权利人:SAKUDA SHOHEI
    摘要:An object of the present invention is to provide an aflatoxin production inhibitor that inhibits aflatoxin production specifically and efficiently, is highly safe, and is practical, and an efficient production method thereof; and a method for controlling aflatoxin contamination that uses the aflatoxin production inhibitor. n Specifically, the present invention relates to an aflatoxin production inhibitor that includes at least one of a dioctatin represented by the following formula (I) and a derivative thereof, as an active ingredient: n n n n n n n n n n n n where, in the formula (I), R represents one of hydrogen and a methyl group. n n n n n The present invention also relates to a method for producing an aflatoxin production inhibitor in which dioctatin is prepared: by a method including culturing a dioctatin-producing microorganism, and at least one of separating and purifying dioctatin from a culture obtained, by centrifugal liquid liquid partition chromatography; or by chemical synthesis. Further, the present invention relates to a method for controlling aflatoxin contamination that includes using the aflatoxin production inhibitor to thereby inhibit aflatoxin production by an aflatoxin-producing microorganism.

    专利号:US-6096782-A
    优先权日:1996-11-22
    标 题:N-(aryl/heteroaryl) amino acid derivatives pharmaceutical compositions comprising same and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
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    主要参考文献

    [参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
    [参考文献]: Geoffrey J Roff, Et Al. A Versatile Chemo-Enzymatic Route To Enantiomerically Pure Beta-Branched Alpha-Amino Acids. J Am Chem Soc. 2004 Apr 7;126(13):4098-9.

    合成参考文献


    摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).
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