专利号:US-2025049714-A1 优先权日:2021-12-09 标题 :Synthesis of ester, carbonate, and carbamate-derived novel biodegradable ionizable lipids from methyl ricinoleate or methyl 12-hydroxystearate and its applications 发明人:ANDERSON DANIEL GRIFFITH; RHYM LUKE HYUNSIK; LI BOWEN; GORDON AKIVA; RAJITH SINGH MANAN; WITTEN JACOB 权利人:MASSACHUSETTS INST TECHNOLOGY 摘要:Provided herein are compounds, such as compounds of Formula (I), and pharmaceutically acceptable salts, hydrates, solvates, polymorphs, co-crystals, tautomers, stereoisomers, and isotopically labeled derivatives thereof, and compositions, methods, uses, and kits thereof. The compounds provided herein are lipids useful for delivery of polynucleotides, such as mRNA, for the treatment and/or prevention of various diseases and conditions (e.g., genetic disease, proliferative disease, hematological disease, neurological disease, liver disease, spleen disease, lung disease, painful condition, psychiatric disorder, musculoskeletal disease, a metabolic disorder, inflammatory disease, or autoimmune disease).
专利号:WO-2023107648-A3 优先权日:2021-12-09 标题:Synthesis of ester, carbonate, and carbamate-derived novel biodegradable ionizable lipids from methyl ricinoleate or methyl 12-hydroxystearate and its applications
专利号:US-9314021-B2 优先权日:2004-11-03 标题 :Formulations containing insect repellent compounds 发明人:SCIALDONE MARK A 权利人:DU PONT 摘要:Dihydronepetalactone, a minor natural constituent of the essential oil of catmints ( Nepeta spp.) such as Nepeta cataria , has been identified as an effective insect repellent compound. Synthesis of dihydronepetalactone may be achieved by hydrogenation of nepetalactone, the major constituent of catmint essential oils. This compound, and compositions thereof, which also has fragrance properties, may be used commercially for its insect repellent properties.
专利号:WO-2023107648-A2 优先权日:2021-12-09 标 题:Synthesis of ester, carbonate, and carbamate-derived novel biodegradable ionizable lipids from methyl ricinoleate or methyl 12-hydroxystearate and its applications
专利号:RU-2413738-C2 优先权日:2005-04-29 标题:Polyesterpolyols having secondary alcohol groups and use thereof in synthesis of polyurethanes, such as flexible foamed polyurethanes
专利号:JP-H05222200-A 优先权日:1991-10-10 标题 :Synthesis of silicone-polyether / alkyl copolymer
参考标题:A General Approach To Intermolecular Olefin Hydroacylation Through Light‐induced Hat Initiation: An Efficient Synthesis Of Long‐chain Aliphatic Ketones And Functionalized Fatty Acids 作者:Subhasis Paul,Joyram Guin |发布日期:2021.3 摘要:Hydroacylation Protocol Applies To A Wide Array Of Substrates Bearing Numerous Functional Groups And Many Complex Structural Units. The Reaction Proves To Be Scalable (Up To 5 G). Different Functionalized Fatty Acids, Petrochemicals And Naturally Occurring Alkanes Can Be Synthesized With This Protocol. A Radical Chain Mechanism Is Implicated In The Process.
合成参考文献
摘要:Hawley, G.G. The Condensed Chemical Dictionary. 9th ed. New York: Van Nostrand Reinhold Co., 1977., p. 570 摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118 摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198