1,5-二氯-2,4-二硝基苯置于四(三苯基膦)钯,Potassium Carbonate,三苯基膦体系中,用 1,4-二氧六环,水,邻二氯苯,甲苯 用作溶剂,化学反应 72.0H,反应生成5,7-二氢-吲哚并[2,3-B]咔唑 参考文献:Polycyclic Aromatic Compounds And Organic Electroluminescent Devices Using The Same 标题:Polycyclic Aromatic Compounds And Organic Electroluminescent Devices Using The Same 摘要:披露了可以应用于有机电致发光器件的各种有机层中的多环芳香化合物.还披露了包括这些多环芳香化合物的有机电致发光器件.这些有机电致发光器件具有高效率,长寿命并且具有极大改善的发光效率.
专利号:US-8399502-B2 优先权日:2008-09-17 标 题 :Analogs of indole-3-carbinol and their use as agents against infection 发明人:JONG LING; JIANG FAMING; LI GAOQUAN; MORTELMANS KRISTIEN 权利人:JONG LING; JIANG FAMING; LI GAOQUAN; MORTELMANS KRISTIEN; STANFORD RES INST INT 摘要:Compounds useful as antibacterial agents are provided. The compounds are analogs of indole-3-carbinol and have a backbone selected from dihydroindolo[2,3-b]carbazole, 2,2′-diindolylmethane, 2′,3-diindolylmethane, and 3,3′-diindolylmethane. The compounds are useful therapeutic and prophylactic treatment of bacterial infections in mammals. Methods of synthesis of the compounds are provided, as are pharmaceutical compositions containing the compounds.
专利号:US-7666897-B2 优先权日:2002-08-20 标题 :Analogs of indole-3-carbinol metabolites as chemotherapeutic and chemopreventive agents 发明人:JONG LING; CHAO WAN-RU 权利人:STANFORD RES INST INT 摘要:Novel compounds useful as chemotherapeutic and chemopreventive agents are provided. The compounds are analogs of indole-3-carbinol metabolites wherein the structures and substituents of the compounds are selected to enhance the compounds' overall efficacy, particularly with respect to therapeutic activity, oral bioavailability, long-term safety, patient tolerability, and therapeutic window. The compounds are useful not only in treatment of cancer but also in prevention of cancer. One preferred class of the novel compounds has the structure of formula (IV) n nwherein:n R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 5A , R 6A , R 7A , R 8A , R 22 and R 23 are defined herein. Pharmaceutical compositions are provided as well, as are methods of synthesis and use.
专利号:US-3041349-A 优先权日:1959-11-09 标 题 :Synthesis of carbazoles 发明人:BEARSE ARTHUR E; HILLENBRAND JR LOUIS J; GROTTA HENRY M 权利人:MARTIN MARIETTA CORP
参考文献:10.1007/s10593-023-03157-3 摘要:Borodkin GI. Carbocation Catalysis in the Synthesis of Heterocyclic Compounds. Chem Heterocycl Comp. 2023 Feb;59(1-2):16–34. doi: 10.1007/s10593-023-03157-3. 参考文献:10.1007/s40843-025-3546-5 摘要:Shi R, Hong W, Zhu S, Cui Z, Li Z, Wu S, Xu W, Gao Z, Liang Y, Jiang H. Organic cocrystals in the NIR window: functional design, controlled synthesis and frontier applications. Sci. China Mater. 2025 Aug 11;68(9):2999–3018. doi: 10.1007/s40843-025-3546-5.