CAS: 1075-76-9; 3-Anilinopropionitrile

该化合物是一种有机化合物,其特征是存在硝酸性功能组和一个附于丙基链的氨基子组,该化合物具有一个联苯组,该组是附属于氨基组的苯环,具有芳香特性;该结构由三碳链(丙烷)组成,其一端为硝基(-CN)组,第二碳为氨基(-NH2)组.这种结构既具有极地特性,也具有非极地特性,在各种有机溶剂中溶解,同时在水中表现出有限的溶解性.该硝基子组的存在表明潜在的再活动,特别是在核分裂性反应中.此外,苯基氨基会参与氢的结合,影响其物理特性,如熔点和沸点.

结构式图片

相似化合物

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欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

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合成工艺路线路线简述

    📜Trans-Hydrido-2-{3-(Phenylamino)Propionitrilo}Bis(Triethylphosphine)Platinum(II) 以 Not Given 用作溶剂,化学反应生成3-(苯氨基)丙腈
    参考文献:Syntheses,Reactions,And Molecular Structures Of Trans-Hydrido(Phenylamido)Bis(Triethylphosphine)Platinum(II) And Trans-Hydridophenoxobis(Triethylphosphine)Platinum(II)
    标题:Syntheses,Reactions,And Molecular Structures Of Trans-Hydrido(Phenylamido)Bis(Triethylphosphine)Platinum(II) And Trans-Hydridophenoxobis(Triethylphosphine)Platinum(II)
    摘要:
    Doi:10.1021/ja00195A031

    专利信息


    专利号:US-4412075-A
    优先权日:1981-01-16
    标题 :Process for the preparation of quinolin-4-ones
    发明人:BAUDOUIN MICHEL; DESBOIS MICHEL
    权利人:RHONE POULENC SANTE
    摘要:1,2,3,4-Tetrahydroquinolin-4-ones of the formula: ##STR1## wherein R represents a hydrogen or halogen atom, an alkyl radical (1 to 4 carbon atoms), an alkoxy radical (1 to 4 carbon atoms) or the trifluoromethyl radical, and R 1 represents a hydrogen atom, an alkyl radical (1 to 4 carbon atoms) or the trifluoromethyl radical, are prepared by cyclizing a 3-anilinopropionic acid of the formula: ##STR2## (wherein R and R 1 are as hereinbefore defined) in a mixture of hydrofluoric acid and boron trifluoride. n The quinolinone products are useful intermediates in the synthesis of therapeutically active substances.

    专利号:US-2007060558-A1
    优先权日:2004-07-30
    标 题 :Hybrid molecules QA where Q is an aminoquinoline and A is an antibiotic residue, the synthesis and uses thereof as antibacterial agents
    发明人:SANCHEZ MURIEL; MEUNIER BERNARD
    权利人:CENTRE NAT RECH SCIENT
    摘要:The invention concerns an aminoquinoline-antibiotic hybrid compound of general formula (I): Q—(Y 1 ) p —(U) p —(Y 2 ) p -A: wherein Q represents an aminoquinoline, (Y 1 ) p (U) p —(Y 2 ) p″ is an optional spacer and A is an antibiotic residue. The invention enables the antibiotic residue activity to be unexpectedly enhanced.

    专利号:JP-2010155798-A
    优先权日:2008-12-26
    标 题:Synthesis of heteroatom-substituted optically active propanenitriles

    专利号:CN-101712688-A
    优先权日:2004-07-30
    标题 :Q is an aminoquinoline and A is a hybrid QA molecule of an antibiotic residue, its synthesis and antibacterial agent application

    专利号:CN-115677534-A
    优先权日:2022-09-22
    标 题 :A kind of raw material of N-cyanoethyl-N-hydroxyethylaniline fully utilizes the production synthesis process

    专利号:CN-111393320-A
    优先权日:2020-03-24
    标 题:A kind of N-cyanoethyl-N-benzylaniline synthesis treatment device

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    📌 第三方产品分析报告

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    合成参考文献


    摘要:Mase, N., Science of Synthesis: Water in Organic Synthesis, (2012) 1, 196.
    摘要:Payne, P. R.; Gagné, M. R., Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis, (2016) 1, 382.
    摘要:Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases., 32(9)(32), 1988
    摘要:Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases., 32(9)(50), 1988
    摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 1985. Acute oral toxicity and repellency of 933 chemicals to house and deer mice. Archives of Environmental Contamination and Toxicology 14:111-129. https://www.aphis.usda.gov/ws/nwrc/chem-effects-db/S_schafer851.pdf
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