CAS: 94051-08-8; Quizalofop-P

• 英文名称Quizalofop-P
• 中文名称精喹禾灵
• IUPAC名称(2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoic acid
• 其它别名(R)-2-(4-((6-chloro-2-quinoxalinyl)oxy)phenoxy)propanoic acid
• CAS编号94051-08-8
• MFCD编号:MFCD00872025
• EINECS号:618-997-1
• 分子式:C17H13ClN2O4
• 分子量:344.75
• 产品CID: 1986374
• 产品分类化学农药原药 → 杀虫剂 → 有机氯杀虫剂

• 相似结构搜索
• InChIKey: ABOOPXYCKNFDNJ-SNVBAGLBSA-N
• InChI=1S/C17H13ClN2O4/c1-10(17(21)22)23-12-3-5-13(6-4-12)24-16-9-19-15-8-11(18)2-7-14(15)20-16/h2-10H,1H3,(H,21,22)/t10-/m1/s1…
• 计算化学: 氢键受体数6.0氢键供体数1.0可旋转键数5.0

物理性质

• 熔点152.00°C - 164.00°C
• 沸点533.3±50.0 °C at 760 mmHg
• 闪点276.3±30.1 °C
• 密度1.4±0.1 g/cm3
• pKa:3.11±0.10(预测)
• PSA:81.54
• LogP:4.05
• 折射率1.649
• 蒸汽压0.0±1.5 mmHg at 25°C
• 溶解性DMSO (Slightly), Chloroform (Slightly), Methanol (Slightly)
• 外观形态白色至棕色粉末
• 储存条件-10 to -25°C

MSDS等安全信息

• GHS象形图
• GHS符号GHS06;
  注释: Skull and crossbones
• 危险类别急性毒性 类别3(经口)
• 警示词Danger(危险)
• 危险描述H301 |吞咽会中毒.
• 防范说明P301+P310
• UN编号UN 2811 6.1 / PGIII
• 危险品标志T
• 安全声明45
• 危险类别码25
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 合成目标产物 Quizalofop-P 主要起始原料 2,6-Dichloroquinoxaline And (R)-(+)-2-(4-Hydroxyphenoxy)Propionic Acid
• 76578-79-5 + 16987-02-3 = 94051-08-8
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Dimethylformamide,Toluene; Rt; 4 H,Reflux
  标题:Synthesis Method Of High-Quality Quizalofog-P-Ethyl
  作者:Zhang,Jianlin; Wu,Zhihong; Chu,Binbin
  参考文献:Guangdong Huagong 日期:2010 卷标:37(5) 页码:150-151]
  
  18671-97-1 + 94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; Rt; 15 - 30 Min,Rt; Rt -> 75 °C; 2 H,75 °C1.2 75 °C; 75 °C -> 145 °C; 6 H,145 °C; 145 °C -> Rt
  标题:Tetrahydro-Isoquinolin-2-Yl-Aryloxy-Phenoxy Alkyl Ketone Compounds And Its Application
  参考文献:China]
  
  18671-97-1 + 94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; Rt; 15 - 30 Min,Rt; 2 H,Rt -> 75 °C1.2 75 °C; 6 H,75 °C -> 145 °C; 145 °C -> Rt1.3 Reagents: Hydrochloric Acid Solvents: Water; Ph 4 - 5
  标题:Fused Hybrid Oxygen Base Phenoxy Carboxylic Acid Derivative And Its Application As Agricultural Herbicide
  参考文献:China]
  
  18671-97-1 + 94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; Rt; 15 - 30 Min,Rt; Rt -> 75 °C; 2 H,75 °C1.2 75 °C -> 145 °C; 6 H,145 °C1.3 Reagents: Hydrochloric Acid Solvents: Water; Ph 4 - 5
  标题:Pyridine-3-Yl Aryloxy Phenoxy Alkyl Acid Ester And Its Application As Agricultural Herbicide
  参考文献:China]
  
  18671-97-1 + 94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide
  标题:Design,Synthesis And Biological Activity Of 2-(4-Aryloxyphenoxy) Propionamides Containing 1,3,4-Thiadiazole
  作者:Hui,Yang Zi
  参考文献:Indian Journal Of Heterocyclic Chemistry 日期:2019 卷标:29(1) 页码:1-4]
  
  112080-05-4 + 94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; Rt; Rt -> 80 °C; 1 H,70 - 80 °C1.2 8 H,70 - 80 °C; 80 °C -> Rt1.3 Reagents: Hydrochloric Acid Solvents: Water; Ph 4 - 5,Cooled
  标题:Synthesis And Herbicidal Activity Of Novel N-Hetrocyclo Containing Nitrogen Methoxy-O-(4-Aryloxy-Phenyl)Lactamide Derivatives
  作者:Liu,Qixing; Huang,Mingzhi; Liu,Aiping; Nie,Siqiao; Lei,Manxiang; Et Al
  参考文献:Youji Huaxue 日期:2014 卷标:34(1) 页码:118-125]
  
  29617-66-1 + 76578-79-5 = 94051-08-8
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Dimethylformamide,Toluene1.2 -1.3 Reagents: Water1.4 Reagents: Hydrochloric Acid Solvents: Water
  标题:Preparation Of (+)-2-[4-(6-Chloro-2-Quinoxalinyloxy)Phenoxy]Propionates
  参考文献:World Intellectual Property Organization]
  
  94050-90-5 = 94051-08-8 [标题:Reaction Conditions
  标题:Synthesis And Antitumor Activity Of N-Pyridyl-2-(4-Aryloxyphenoxy)Propionamide
  作者:Liu,Qi-Xing; Liu,Ai-Ping; Huang,Ming-Zhi
  参考文献:Jingxi Huagong 日期:2016 卷标:33(2) 页码:176-181]
  
  18671-97-1 + 94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Carbonate; 70 - 80 °C
  标题:Synthesis And Herbicidal Activity Of N-Arylmethyl-2-(4-Arylxoyphenoxy) Propionamide
  作者:Liu,Qixing; Hu,Aixi; Wang,Xiaoguang; Lei,Manxiang; Ou,Xiaoming; Et Al
  参考文献:Gaodeng Xuexiao Huaxue Xuebao 日期:2014 卷标:35(2) 页码:262-269]
  
  18671-97-1 + 94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; Rt; 15 - 30 Min,Rt; 1 - 2 H,Rt -> 85 °C1.2 60 - 80 °C; 4 - 6 H,80 °C -> 145 °C; 145 °C -> Rt1.3 Reagents: Hydrochloric Acid Solvents: Water; Ph 4 - 5,Cooled
  标题:N-Oxy Fused O-Heterocyclic Phenoxy-Carboxylic Acid Amide Compound,Its Preparation Method And Application
  参考文献:China]
  
  18671-97-1 + 94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; Rt; 15 - 30 Min,Rt; Rt -> 75 °C; 2 H,75 °C1.2 75 °C; 6 H,75 °C -> 145 °C; 145 °C -> Rt1.3 Reagents: Hydrochloric Acid Solvents: Water; Ph 4 - 5,Cooled
  标题:Naphthyl 2-(4-Aryloxyphenoxy)Alkanoate Compounds And Their Application In Agricultural Herbicides
  参考文献:China]
  
  18671-97-1 + 94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; 15 - 30 Min,Rt; Rt -> 75 °C; 2 H,75 °C1.2 6 H,75 °C -> 140 °C; 140 °C -> Rt1.3 Reagents: Hydrochloric Acid Solvents: Water; Ph 4 - 5,Rt
  标题:Preparation Of Aryloxyphenoxy Alkyl Acid Derivatives As Herbicides
  参考文献:China]
  
  18671-97-1 + 94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide
  标题:Synthesis And Herbicidal Activity Of 2-(4-Aryloxyphenoxy)Propionamides
  作者:Hui,Yang Zi; Hao,Tian; Chuan,Zhang Shi; Tian,Li Guang
  参考文献:Journal Of Chemical And Pharmaceutical Research 日期:2018 卷标:10(4) 页码:104-106]
  
  18671-97-1 + 94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide
  标题:Synthesis And Herbicidal Activity Of 2-(4-Aryloxyphenoxy)Propionamides
  作者:Hui,Yang Zi
  参考文献:Indian Journal Of Heterocyclic Chemistry 日期:2018 卷标:28(3) 页码:385-388]
  
  94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Carbonate
  标题:Synthesis And Herbicidal Activity Of N-(2,2-Dimethyl-7-Alkoxy-2,3-Dihydrobenzofuran-5-Yl)-2-(4-Arylxoyphenoxy)Propionamides
  作者:Lin,Ding; Xiao,Mengwu; Yang,Zihui; Li,Beibei; Hu,Aixi; Et Al
  参考文献:Chemical Research In Chinese Universities 日期:2017 卷标:33(1) 页码:74-79]
  
  18671-97-1 + 94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; 1 H,75 °C1.2 75 °C; 7 H,140 °C; Cooled1.3 Reagents: Hydrochloric Acid Solvents: Water; Ph 4 - 5
  标题:Synthesis And Herbicidal Activity Of Novel N-Allyloxy/propargyloxy Aryloxyphenoxy Propionamide Derivatives
  作者:Liu,Qixing; Huang,Mingzhi; Liu,Aiping; Hu,Aixi; Lei,Manxiang; Et Al
  参考文献:Chemical Research In Chinese Universities 日期:2016 卷标:32(2) 页码:188-194]
  
  18671-97-1 + 94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Hydroxide Solvents: Dimethylformamide; 1 H,70 - 80 °C1.2 5 - 6 H,130 - 140 °C; 140 °C -> Rt1.3 Reagents: Hydrochloric Acid Solvents: Water; Ph 4 - 5,Cooled
  标题:2-[4-(Quinoxalin-2-Oxy)Phenoxy]Amide Useful In Treatment Of Cervical Cancer And Its Preparation
  参考文献:China]
  
  18671-97-1 + 94050-90-5 = 94051-08-8
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; Rt; 1 H,70 - 80 °C1.2 5 - 6 H,130 - 140 °C; 140 °C -> Rt1.3 Reagents: Hydrochloric Acid Solvents: Water; Cooled; Ph 4 - 5,Cooled
  标题:Preparation Of Drugs 2-[4-(Quinoxalin-2-Yloxy)Phenoxy]Alkylamide And Optical Isomers For Treating Lung Adenocarcinoma A549
  参考文献:China]
  
  100646-51-3 = 94051-08-8
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Water; Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 2 - 3,Rt
  标题:Synthesis And Biological Activities Of Novel Quizalofop-Ethyl Derivatives
  作者:Ju,Guang-Xiu; Chen,Wei-Yan; Xu,Liang-Zhong
  参考文献:Xiandai Nongyao 日期:2015 卷标:14(4) 页码:5-7]
  
  29617-66-1 + 76578-79-5 = 94051-08-8
  反应条件:1.1 Reagents: Phenol,4-[(6-Chloro-2-Quinoxalinyl)Oxy]-,Barium Salt (2:1) Solvents: Dimethylformamide1.2 -
  标题:Preparation Of Aryloxypropionic Acids As Herbicides
  参考文献:Japan

海关参考信息

• 2903919090-氯苯
  2905122000-异丙醇
  2905310000-1,2-乙二醇
  2905320000-1,2-丙二醇
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

其他信息查阅

• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管