CAS: 529-37-3; Quinolin-4(1H)-One

该化合物是一个环状结构引信,包括一个肾上腺素和碳基化合物的环状结构的六环有机化合物,该化合物一般是黄色至褐色晶状固体,因其芳香特性而闻名,有助于其稳定性和再活性;在乙醇和二甲基硫氧化物等有机溶剂中溶解,但水溶性有限.

结构式图片

上下游产品

CAS号15568-92-0 5-(ANILINOMETHY... | CAS号613-89-8 2-氨基苯乙酮 | CAS号109-94-4 甲酸乙酯 | CAS号87488-61-7 3-(dimethylamin... | CAS号153813-81-1 3-(dimethylamin... | CAS号4295-36-7 2,3-二氢-1H-喹啉-4-酮 | CAS号5257-06-7 Formamide,N-(2-... | CAS号3039-74-5 4-Quinolinol, 1... | CAS号577-59-3 2-硝基苯乙酮 | CAS号108325-70-8 2-(hydroxymethy... | CAS号607-31-8 4-甲氧基喹啉 | CAS号3689-24-5 治螟磷 | CAS号93516-19-9 | CAS号50332-66-6 3-硝基-4-羟基喹啉 | CAS号105-13-5 对甲氧基苄醇 | CAS号91-22-5 喹啉 | CAS号23833-99-0 4-氯-8-硝基喹啉 | CAS号24220-92-6 1-benzylquinoli... | CAS号611-35-8 4-氯喹啉

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    专利号:US-12421534-B2
    优先权日:2021-11-10
    标 题 :Engineered enzymes and method for the synthesis of diverse tyrosine analogs
    发明人:ALMHJELL PATRICK J; ARNOLD FRANCES H
    权利人:CALIFORNIA INST OF TECHN
    摘要:Provided herein is an engineered tryptophan synthase β-subunit (TrpB) that catalyzes the synthesis of tyrosine, tyrosine analogs, or salts thereof. Also provided herein are methods for preparing tyrosine, tyrosine analogs, or a salt thereof using the engineered TrpB described herein.

    专利号:US-2021107859-A1
    优先权日:2018-04-06
    标题 :A process for the synthesis of carbon labeled organic compounds
    发明人:AUDISIO DAVIDE; CANTAT THIBAULT; DESTRO GIANLUCA
    权利人:COMMISSARIAT ENERGIE ATOMIQUE
    摘要:A process for the synthesis of a carbon labeled organic compound containing a carbon labeled carboxyl group is described. A method of using carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; a process for manufacturing labeled pharmaceuticals and agrochemicals comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; and a process for producing tracers comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure are also described.

    专利号:US-2006167025-A1
    优先权日:2004-12-22
    标 题:Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs
    发明人:BERGER MARKUS; SCHMEES NORBERT; SCHAECKE HEIKE; BAURLE STEFAN; REHWINKEL HARTMUT; MENGEL ANNE; KROLIKIEWICZ KONRAD; GROSSBACH DANJA; VOIGTLAENDER DAVID
    权利人:BERGER MARKUS; SCHMEES NORBERT; SCHAECKE HEIKE; BAURLE STEFAN; REHWINKEL HARTMUT; MENGEL ANNE; KROLIKIEWICZ KONRAD; GROSSBACH DANJA; VOIGTLAENDER DAVID
    摘要:The invention relates to tricyclic amino alcohols of general formula (I) n nmethod for synthesis of same and use of same as anti-inflammatory agents.

    专利号:US-8735586-B2
    优先权日:2007-06-26
    标 题 :Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles
    发明人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR
    权利人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR; SANOFI SA
    摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, n nwherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct copper catalyzed regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

    专利号:WO-9611194-A1
    优先权日:1994-10-06
    标题:Pyridonecarboxylic acid derivative and intermediate for the synthesis of the same
    发明人:OKADA HIDETSUGU; CHIBA KATSUMI; TOMINAGA YUKIO; MINAMI AKIRA
    权利人:DAINIPPON PHARMACEUTICAL CO; OKADA HIDETSUGU; CHIBA KATSUMI; TOMINAGA YUKIO; MINAMI AKIRA
    摘要:A pyridonecarboxylic acid derivative represented by general formula (I), an ester and a salt thereof, an antibacterial agent containing the same, and a bicyclic amine compound serving as a direct intermediate for the synthesis of the pyridonecarboxylic acid derivative, wherein R represents cycloalkyl, optionally substituted phenyl, etc.; G represents carbon, etc.; A represents C-Z (Z being hydrogen, halogeno, lower alkoxy, etc.) or nitrogen; X represents hydrogen, amino, etc.; Y represents hydrogen or halogeno; m is an integer of 1 to 3; and W represents -(CH2)nN(R1)R2 (R1 and R2 being the same or different and each representing hydrogen, lower alkyl, etc., and n being an integer of 0 or 1).

    专利号:EP-2173747-B1
    优先权日:2007-06-26
    标 题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
    发明人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; R KYEN OMAR; URMANN MATHIAS; HALLAND NIS
    权利人:SANOFI SA
    摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R1; R2; R3; R4; J1; J2; J3; J4 and G have the meanings indicated in the claims. The present invention provides a direct metal, e.g. palladium or copper, catalyzed, regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

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    合成参考文献


    参考文献:10.1007/s00253-010-2455-0
    摘要:Fetzner S, Steiner RA. Cofactor-independent oxidases and oxygenases. Applied Microbiology and Biotechnology. 2010 Feb 16;86(3):791–804. doi: 10.1007/s00253-010-2455-0.
    参考文献:10.1021/jm200370y
    摘要:Sabatini S, Gosetto F, Manfroni G, Tabarrini O, Kaatz GW, Patel D, Cecchetti V. Evolution from a natural flavones nucleus to obtain 2-(4-Propoxyphenyl)quinoline derivatives as potent inhibitors of the S. aureus NorA efflux pump. J Med Chem. 2011 Aug 25;54(16):5722–36. doi: 10.1021/jm200370y.
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