CAS: 51605-32-4; Ethyl 5-Methyl-1H-Imidazole-4-Carboxylate

相似化合物

29636-87-1 68282-53-1 38585-62-5

2-Acetoxy-Acetoacetic Acid Ethyl Ester置于盐酸体系中,化学反应生成 4-甲基-5-咪唑甲酸乙酯
参考文献:Boehme; Schneider,Chemische Berichte,1958,Vol. 91,P. 988,992
标题:Boehme; Schneider,Chemische Berichte,1958,Vol. 91,P. 988,992

专利信息

专利号:US-8946410-B2
优先权日:2009-10-08
标 题 :Automated radiosynthesis
发明人：WOODCRAFT JOHN; JONES L CLARE; GAETA ALESSANDRA; TRIGG JOHN WILLIAM; JONES ALEXANDER PAUL; PLANT STUART; JACKSON ALEXANDER
权利人:WOODCRAFT JOHN; JONES L CLARE; GAETA ALESSANDRA; TRIGG JOHN WILLIAM; JONES ALEXANDER PAUL; PLANT STUART; JACKSON ALEXANDER; GE HEALTHCARE LTD
摘要:The present invention provides a method to obtain radiofluorinated compounds useful for in vivo imaging GABA A receptors. The method of the invention is high-yielding and may conveniently be carried out on an automated synthesizer such as Fastlabâ„¢. A further aspect of the invention is a cassette suitable for carrying out the automated method of synthesis of the invention. Novel precursor compounds useful in the method of the invention are also provided, as are a number of novel compounds obtained by the method of the invention.

专利号:US-8937184-B2
优先权日:2005-02-16
标 题:1H-imidazole derivatives as cannabinoid CB2 receptor modulators
发明人：LANGE JOSEPHUS H M; VAN STUIVENBERG HERMAN H; VAN VLIET BERNARD J
权利人:LANGE JOSEPHUS H M; VAN STUIVENBERG HERMAN H; VAN VLIET BERNARD J; ABBVIE BV
摘要:The invention relates to a group of 1H-imidazole derivatives which are modulators of cannabinoid CB 2 receptors, to methods for the preparation of these compounds, to novel intermediates useful for the synthesis of said imidazole derivatives, to methods for the preparation of these intermediates, to pharmaceutical compositions containing one or more of these 1H-imidazole derivatives as active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of disorders in which cannabinoid CB 2 receptors are involved. n The compounds have the general formula (I) n nwherein R 1 -R 4 have the meanings given in the specification.