CAS: 40963-14-2; 2-Amino-2,3-Dimethylbutyramide

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CAS号13893-53-3 2-氨基-2,3-二甲基丁腈 | CAS号1336-21-6 氨水 | CAS号81335-37-7 灭草喹 | CAS号81334-34-1 灭草烟 | CAS号81335-77-5 咪草烟 | CAS号4378-19-2 2-amino-2,3-dim... | CAS号90376-98-0 (R)-ALPHA-(4-BR...

2-氨基-2,3-二甲基丁腈置于ammonium Hydroxide,双氧水体系中,化学反应生成 2-氨基-2,3-二甲基丁酰胺
参考文献:Preparation,1H And 13C NMR Spectra Of Substituted 2-Benzoylaminocarboxamides
标题:Preparation,1H And 13C NMR Spectra Of Substituted 2-Benzoylaminocarboxamides
摘要:一种基于咪唑啉酮的新型除草剂自1983年起由美国赛诺美公司推出,商业名称为arsenal,Pursuit,Scepter,Assert等.这些化合物能够消灭双子叶杂草,对哺乳动物和鱼类几乎无毒(ld50 大鼠-500 毫克/千克,Ld50 鳟鱼-300 毫克/千克),根据ames试验结果,这些化合物不具有致突变性.本研究的目的是合成取代的2-苯甲酰氨基羧酰胺,作为制备咪唑啉酮和潜在生物活性物质的起始原料(式 I-Iii).
DOI:10.1135/cccc19950150

专利信息

专利号:US-2023183177-A1
优先权日:2020-04-24
标题:Enantioselective chemo-enzymatic synthesis of optically active amino amide compounds
发明人：GRILL BIRGIT; WINKLER MARGIT; SCHWAB HELMUT; STROHMEIER GERNOT; DONSBACH KAI; WALDVOGEL SIEGFRIED R; ARNDT SEBASTIAN; WEIS DOMINIK
权利人:PHARMAZELL GMBH
摘要:The present invention relates to a novel biocatalytic process for the stereoselective preparation of alpha amino amide compounds catalyzed by NHase enzymes. A further aspect of the invention relates to novel NHase enzymes as well as further improved NHase enzyme mutants, nucleic acid molecules encoding these enzymes, recombinant microorganisms suitable for preparing such enzymes and mutants. Another aspect of the invention relates to a chemo-biocatalytic process for the preparation of lactam compounds comprising the new catalytic process for the preparation of alpha amino amide compounds catalyzed by NHase enzymes, as well as the chemical oxidation of the alpha amino amide by applying certain chemical oxidation catalysts suitable for converting the alpha amino amide under retention of its stereochemical configuration to the respective lactam. The novel chemo-biocatalytic process is particularly suited for the synthesis of valuable pharmaceutical compounds, like in particular (S)-Levetiracetam.

专利号:WO-2021214283-A1
优先权日:2020-04-24
标题 :Enantioselective chemo-enzymatic synthesis of optically active amino amide compounds

专利号:EP-4139468-A1
优先权日:2020-04-24
标题 :Enantioselective chemo-enzymatic synthesis of optically active amino amide compounds

专利号:KR-20230005242-A
优先权日:2020-04-24
标 题 :Enantioselective chemo-enzymatic synthesis of optically active amino amide compounds

专利号:CN-103524485-A
优先权日:2013-09-10
标题:A method for continuous synthesis of imazethapyr

专利号:CN-114478477-A
优先权日:2022-01-27
标题:A kind of synthesis technology of imazamox