专利号:US-9315483-B2 优先权日:2007-09-13 标题 :Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof 发明人:JONES ANDREW D; ZELLE ROBERT E; SILVERMAN I ROBERT 权利人:CONCERT PHARMACEUTICALS INC 摘要:The present invention provides a convenient and efficient process for the synthesis of d 2 -benzo[d][1,3]dioxoles.
专利号:US-9597327-B2 优先权日:2005-05-25 标 题:Synthesis of (R)-N-methylnaltrexone 发明人:DOSHAN HAROLD D; PEREZ JULIO 权利人:PROGENICS PHARM INC 摘要:This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.
专利号:US-7501434-B2 优先权日:2006-08-04 标 题 :6-carboxy-normorphinan derivatives, synthesis and uses thereof 发明人:SHAH SYED M; ALI KADUM A; KONG FANGMING; ZHU TIANMIN; GOMBAR CHARLES T 权利人:WYETH CORP 摘要:The present invention relates to compounds of formula I, synthesis thereof, and methods of using the same.
专利号:US-7674904-B2 优先权日:2005-05-25 标 题 :Synthesis of R-N-methylnaltrexone
专利号:US-2007099946-A1 优先权日:2005-05-25 标 题:Synthesis of R-N-methylnaltrexone
专利号:WO-2009035652-A1 优先权日:2007-09-13 标 题 :Synthesis of deuterated catechols and benzo[d][1,3] dioxoles and derivatives thereof