3-氟苯胺 反应生成 N-(氯乙酰)-3-氟苯胺 参考文献:Acetamides And Benzamides That Are Useful In Treating Sexual Dysfunction 标题:Acetamides And Benzamides That Are Useful In Treating Sexual Dysfunction 摘要:本发明涉及使用式(I)的化合物治疗性功能障碍,以及含有式(I)化合物的组合物用于治疗性功能障碍.
专利号:WO-2021038419-A1 优先权日:2019-08-23 标题 :Kinase inhibitors and methods of synthesis and treatment 发明人:ZAVORONKOVS ALEKSANDRS; IVANENKOV YAN; POLYKOVSKIY DANIIL; ALIPER ALEKSANDR 权利人:INSILICO MEDICINE IP LTD 摘要:Compounds that function as kinase inhibitors are provided. The kinase inhibitors can have any structure of the formulae provided herein, such as shown for Compounds 1-4. A pharmaceutical composition can include: the compound of one of the embodiments; and a pharmaceutically acceptable carrier having the compound. A method of inhibiting a kinase can include: providing the compound of one of the embodiments described herein to the kinase such that the kinase is inhibited. The methods can include inhibiting DDR1 and/or DDR2, and thereby providing a modulation or decrease in the activity of DDR1 and/or DDR2. This decrease in DDR1 and/or DDR2 activity can be used as therapy to treat conditions related to DDR1 and/or DDR2 activity, such as fibrosis, cancer, and others.
专利号:US-10954197-B2 优先权日:2017-03-08 标 题 :Cathepsin-D and angiogenesis inhibitors and compositions thereof for treating breast cancer 发明人:YOGEESWARI PERUMAL 权利人:YOGEES BIOINNOVATIONS PRIVATE LTD 摘要:Cathepsin-D and angiogenesis inhibitors and compositions thereof for treating breast cancer are provided. More particularly, the embodiments relate to the design and synthesis of inhibitors of Cathepsin D, which exhibits antiproliferative activity and also inhibits angiogenesis. Also provided are compositions thereof for treating breast cancer.
专利号:CN-104230762-B 优先权日:2014-08-28 标题:A kind of benzenesulfonamides of phosphinylidyne-containing amine group and Synthesis and applications thereof
专利号:RU-2400471-C1 优先权日:2009-04-30 标 题:N-substituted derivatives of oxamic acid thiohydrazides, synthesis method and use thereof