CAS: 31181-90-5; 5-Bromopicolinaldehyde

相似化合物

29682-15-3 88139-91-7 97483-77-7

上下游产品

CAS号624-28-2 2,5-二溴吡啶 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号97483-77-7 5-溴-2-氰基吡啶 | CAS号223463-13-6 5-溴-2-碘吡啶 | CAS号364794-27-4 5-溴-2-(二溴甲基)吡啶 | CAS号88139-91-7 5-溴-2-吡啶甲醇 | CAS号3430-13-5 5-溴-2-甲基吡啶 | CAS号31181-74-5 2-acetoxymethyl... | CAS号31181-64-3 2-甲基-5-溴吡啶 N-氧化物 | CAS号1114475-05-6 N-(6-甲氧基-3-吡啶)-... | CAS号30766-11-1 5-溴-2-羧基吡啶 | CAS号294851-95-9 4-[(5-溴-2-吡啶)甲基]-吗啉 | CAS号88139-91-7 5-溴-2-吡啶甲醇 | CAS号97483-77-7 5-溴-2-氰基吡啶 | CAS号845827-13-6 5-溴-2-二氟甲基吡啶 | CAS号741709-63-7 2-氰基吡啶-5-硼酸频那酯 | CAS号1044209-33-7 5-溴-2-(二乙氧基甲基)吡啶 | CAS号586-98-1 吡啶甲醇 | CAS号364794-78-5 5-溴-2-哌啶基-1-甲基吡啶

2-甲基-5-溴吡啶-N-氧化物置于盐酸,草酰氯,二甲基亚砜,三乙胺体系中,用 二氯甲烷 作为反应溶剂,化学反应生成 5-溴-2-吡啶甲醛
参考文献:三唑并吡啶.18.对三唑并吡啶的亲核取代反应;2,2'-联吡啶的新途径
标题:三唑并吡啶.18.对三唑并吡啶的亲核取代反应;2,2'-联吡啶的新途径
摘要:描述了一些5-,6-和7-卤代三唑并吡啶的合成,以及它们与亲核试剂的反应.7,7'-双氮杂吡啶吡啶的形成提供了2,2'-联吡啶的新合成.
DOI:10.1016/s0040-4020(97)00491-2

专利信息

专利号:US-2025129021-A1
优先权日:2023-09-19
标 题:Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I), Formula (V)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:US-6635767-B2
优先权日:2000-05-23
标 题 :Synthesis of heteroarylamine intermediate compounds
发明人：SONG JINHUA J; YEE NATHAN K; KAPADIA SURESH R
权利人:BOEHRINGER INGELHEIM PHARMA
摘要:Disclosed are novel 2-(5-halopyridyl) and 2-(5-halopyrimidinyl) magnesium halides, processes of making and their use in the efficient synthesis in their respective 5-halo-2-substituted pyridines and pyrimidines.

专利号:US-6822093-B2
优先权日:2000-05-23
标题 :Synthesis of heteroarylamine intermediate compounds
发明人：SONG JINHUA J; YEE NATHAN K
权利人:BOEHRINGER INGELHEIM PHARMA
摘要:Disclosed are novel 2-(5-halopyridyl) and 2-(5-halopyrimidinyl) magnesium halides, processes of making and their use in the efficient synthesis in their respective 5-halo-2-substituted pyridines and pyrimidines.

专利号:US-9376400-B2
优先权日:2005-06-08
标 题:Process for the synthesis of triazoles
发明人：CHEN SHILI; LOU RONGLIANG; WU YUSHENG; ZHOU JIACHENG; HANSELMANN ROGER
权利人:MELINTA THERAPEUTICS INC
摘要:The present invention relates to processes for the preparation of triazoles. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.

专利号:US-10287265-B2
优先权日:2015-03-09
标 题 :Enantiomers of 8-hydroxyquinoline derivatives and the synthesis thereof
发明人：Puskás László; Kanizsai István; PILLOT THIERRY; GYURIS Márió; Szabó András; Takács Ferenc; Hackler László
权利人:AVIDIN CO LTD; SONEAS RES CO LTD; SYNAGING SAS
摘要:Our invention relates to novel enantiomer derivatives of 8-hydroxyquinoline derivatives with general formula (I) and (II) and the synthesis thereof and pharmaceutically acceptable salts and metal complexes thereof, and the medicinal and/or pharmaceutical compositions comprising these compounds. n n n n n n n n n n The essence of the subject matter of the invention relates to the fact that prior art discloses the biological effect and characteristics only of the racemic products, the novel enantiomer derivatives according to the invention appear in our application for the first. n The subject matter of the invention furthermore relates to a novel, stereoselective synthesis for the preparation of the novel enantiomer derivatives according to the invention. The novel medicinal and/or pharmaceutical compositions comprising these enantiomers are suitable for the treatment of the named diseases, and the enanatiomers are used for manufacture of these compositions. These applications for manufacture of the compositions are also the subject matters of the invention. The compounds according to the invention can be used preferably as cytoprotective, neuroprotective, cardioprotective, anxiolytic and antidepressant agent for treatment of neuropsychiatric and neurologic diseases and diseases in connections with transplantations and with ischemia and reperfusion injuries thereof, and inhibition of organ, advantageously skin graft rejection. According to our studies the R-enantiomer has either sole or high biological effect in some cases.

专利号:US-2003135046-A1
优先权日:2000-05-23
标题 :Synthesis of heteroarylamine intermediate compounds