CAS: 17833-53-3; 2-(Methylamino)Succinic Acid

该化合物是一种氨基酸衍生物,其特征是附于亚麻硫氮原子的甲基组,该化合物是一种非蛋白性氨基酸,在翻译过程中没有被吸收到蛋白质中,以其作为...

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CAS号108-31-6 顺酐 | CAS号110-16-7 马来酸 | CAS号74-89-5 氨基甲烷 | CAS号923-06-8 溴代丁二酸 | CAS号144300-47-0 N-methylasparti... | CAS号6384-92-5 N-甲基-D-天冬氨酸水合物

合成工艺路线路线简述

    Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于barium Dihydroxide体系中,化学反应生成N-甲基-Dl-天冬酸(一水)
    参考文献:Koerner; Menozzi,Gazzetta Chimica Italiana,1889,Vol. 19,P. 427
    标题:Koerner; Menozzi,Gazzetta Chimica Italiana,1889,Vol. 19,P. 427

    海关参考信息

    专利信息


    专利号:US-2024067674-A1
    优先权日:2020-12-28
    标 题 :Method for loading amino acid on resin for solid-phase synthesis
    发明人:SEKITA HIROKO; KOMIYA SHIO; DAN KATSUNORI
    权利人:CHUGAI PHARMACEUTICAL CO LTD
    摘要:An object of the present invention is to provide a method for efficiently producing a peptide compound of high purity at a high yield. It was found that an amino acid can be efficiently loaded on a resin for solid-phase synthesis by bringing an amino acid solution containing a specific solvent into contact with a resin for solid-phase synthesis that has been swollen with a specific solvent, thereby solving such problem.

    专利号:US-2024400861-A1
    优先权日:2021-10-01
    标题 :Triazole- And/Or Triazolium-Based Polymers And Copolymers As Additives For Chemical Mechanical Planarization Slurries
    发明人:LARBIG GREGOR; KIRSCH PEER; HENGST MATTHIAS; SHI XIAOBO; STENDER MATTHIAS
    权利人:VERSUM MAT US LLC
    摘要:Synthesis of triazole- and/or triazolium-based polymers is disclosed. Chemical Mechanical Planarization (CMP) slurries comprise abrasives; activator; oxidizing agent; additive comprising triazole- and/or triazolium-based polymers; and water. The use of the synthesized triazole- and/or triazolium-based polymers in the CMP slurries reduces dishing and erosion in highly selective tungsten slurries.

    专利号:US-5892038-A
    优先权日:1997-12-08
    标 题 :Hydroxy-amino acid amides
    发明人:DOLLE III ROLAND ELLWOOD; PATEL HITESH K
    权利人:PHARMACOPEIA INC
    摘要:Compounds of Formula I I are disclosed as inhibitors of plasmepsin and cathepsin D. The compounds are therefore useful to treat diseases such as malaria. In preferred compounds of formula I, Y is the residue of an N-acylated amino acid, a substituted 4-aminoproline or a substituted piperazinealkanoic acid. Intermediates in the solid phase synthesis of compounds of formula I, in which the compounds are attached to a solid support, are also disclosed.

    专利号:US-6245919-B1
    优先权日:1996-06-28
    标 题:Cyclopropylglycine derivatives and agonists for metabotronic L-glutamate receptors
    发明人:SHINOZAKI HARUHIKO; TAGUCHI TAKEO; ISHIDA MICHIKO
    权利人:SHINOZAKI HARUHIKO; TAGUSHI TAKEO; NIPPON CHEMIPHAR CO
    摘要:A cyclopropylglycine derivative having the following formula:and an intermediate compound for the synthesis of the cyclopropylglycine derivative are novel compounds. The cyclopropylglycine derivative shows a selectivity higher than that of the known agonists to metabotropic L-glutamate receptors, and therefore is a metabotropic type agonist to L-glutamate which has excellent characteristics.

    专利号:TW-202100523-A
    优先权日:2013-11-08
    标题:Process for the synthesis of an indoleamine 2,3-dioxygenase inhibitor

    专利号:WO-2007107319-A1
    优先权日:2006-03-17
    标题:Isolation, structure determination, synthesis and bioactivity of damipipecolin and damituricin
    发明人:AIELLO ANNA; GIORDANO ANTONELLA; FATTORUSSO ERNESTO; MENNA MARIALUISA; SCHROEDER HEINZ C; MUELLER WERNER E G
    权利人:BIOTECMARIN GMBH; AIELLO ANNA; GIORDANO ANTONELLA; FATTORUSSO ERNESTO; MENNA MARIALUISA; SCHROEDER HEINZ C; MUELLER WERNER E G
    摘要:Two new bromopyrrole alkaloids, compounds (1) and (2), have been isolated from the Mediterranean sponge Axinella damicÏ…rnis, and their structure established through spectroscopic methods. Compounds (1) and (2 )display a modulating effect of the serotonin receptor activity and neuroprotective activity in vitro.
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    主要参考文献

    [参考文献]: G R Lauretti, Et Al. The Activity Of Opioid Analgesics In Seizure Models Utilizing N-Methyl-Dl-Aspartic Acid, Kainic Acid, Bicuculline And Pentylenetetrazole. Neuropharmacology. 1994 Feb;33(2):155-60.
    [参考文献]: S J Czuczwar, Et Al. Antagonism Of N-Methyl-D,L-Aspartic Acid-Induced Convulsions By Antiepileptic Drugs And Other Agents. Eur J Pharmacol. 1985 Feb 5;108(3):273-80

    合成参考文献


    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    参考文献:10.1016/j.cbpc.2004.02.010
    摘要:Leatherland JF, Lin L, Renaud R. Effect of glutamate on basal steroidogenesis by ovarian follicles of rainbow trout (Oncorhynchus mykiss). Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 2004 May;138(1):71–80. doi: 10.1016/j.cbpc.2004.02.010.
    参考文献:10.1152/jn.00625.2003
    摘要:Einum JF, Buchanan JT. Reticulospinal neurons receive direct spinobulbar inputs during locomotor activity in lamprey. J Neurophysiol. 2004 Sep;92(3):1384–90. doi: 10.1152/jn.00625.2003.
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