油酰氯置于n,N-二异丙基乙胺,Lithium Hydroxide体系中,用 甲醇,乙醇,二氯甲烷,水 用作溶剂,化学反应 12.0H,反应生成油酰肌氨酸
参考文献:Design And Synthesis Of Lipids For The Fabrication Of Functional Lipidic Cubic-Phase Biomaterials
标题:Design And Synthesis Of Lipids For The Fabrication Of Functional Lipidic Cubic-Phase Biomaterials
摘要:A Series Of Novel Lipids With Designed Functionalities Were Synthesized. These Lipids Are Based On Conjugation Of Alpha-Amino Acids And Their Esters,Cationic,Anionic,Neutral,And Photochromic Moieties To The Lipophilic 9-Cis octadecenyl Chains By Amide,Ester,Thioester,Or Amine Bonds. Because Of The Plasticity Of Lipidic Cubic Phases,It Is Envisaged That When Mixed With Monooleoyl-Rac-Glycerol (Monoolein,Mo) And Water At Appropriate Proportions,They Would Assemble To Form Bicontinuous Lipidic Cubic Phases (Lcps) That Exhibit The Well-Known Material Properties Of Lcps Such As Phase Stability,Optical Transparency,And Chemical Permeability. Moreover,Due To The Nature And Position Of The Functionality At The Headgroup Region,We Envision Them To Perform As Functional Materials By Design.
Doi:10.1021/jo301659C