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acetylamino-cyclopentylmethyl-malonic acid diethyl ester cyclopentylmethyl bromide 海关参考信息
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专利信息
专利号:US-2023037284-A9
优先权日:2018-11-30
标题:Combination therapy of peptidomimetic macrocycles
发明人:GUERLAVAIS VINCENT; ANNIS DAVID ALLEN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
专利号:WO-2021130756-A1
优先权日:2019-12-25
标题:Combinations of non-protein amino acids and acetolactate synthase enzyme inhibitors
发明人:KLIPCAN LIRON; VAN-OSS PINHASI RUTH
权利人:THE STATE OF ISRAEL MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT AGRICULTURAL RES ORGANIZATION ARO VO
摘要:The present invention provides compositions and methods for disrupting protein synthesis in plant cells.
专利号:WO-2024148312-A1
优先权日:2023-01-06
标题 :Compositions, systems, and methods for amino acid synthesis
发明人:YANG YANG; CHENG LEI; BO ZHIYU
权利人:UNIV CALIFORNIA
摘要:A method of forming a non-canonical amino acid includes contacting a substrate, a photocatalyst, and an amino acid with a pyridoxal enzyme in a solution and providing light sufficient to form the non-canonical amino acid from the solution. Compositions, systems, and methods for amino acid synthesis are included. Further, engineered enzymes to catalyze diverse C-C and C-heteroatom bond forming reactions are included.
专利号:US-2018371021-A1
优先权日:2017-05-11
标 题 :Peptidomimetic macrocycles and uses thereof
发明人:AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
专利号:US-11091522-B2
优先权日:2018-07-23
标题 :Peptidomimetic macrocycles and uses thereof
发明人:AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN; ANNIS DAVID ALLEN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
专利号:US-11021501-B2
优先权日:2015-03-30
标题:Creatine phosphate analog prodrugs, compositions and methods of use thereof
发明人:BRUBAKER WILLIAM F
权利人:FARMINGTON PHARMA DEV
摘要:The invention describes membrane permeable creatine phosphate analog prodrugs, pharmaceutical compositions comprising membrane permeable creatine phosphate analog prodrugs, and methods of treating diseases such as ischemia, heart failure, neurodegenerative disorders and genetic disorders affecting the creatine kinase system comprising administering creatine phosphate analog prodrugs or pharmaceutical compositions thereof. The invention also describes treating a genetic disease affecting the creatine kinase system, such as, for example, a creatine transporter disorder or a creatine synthesis disorder comprising administering creatine phosphate analog prodrugs or pharmaceutical compositions thereof.