CAS: 5445-51-2; Cyclobutane-1,1-Dicarboxylic Acid

相似化合物

10224-72-3 3779-29-1 4415-73-0

上下游产品

CAS号109-64-8 1,3-二溴丙烷 | CAS号105-53-3 丙二酸二乙酯 | CAS号30491-91-9 1-氰基环丁烷羧酸 | CAS号28246-87-9 1-氰基环丁基羧酸乙酯 | CAS号60-29-7 乙醚 | CAS号300687-20-1 (3-iodo-propyl)... | CAS号108-88-3 甲苯 | CAS号109364-41-2 cyclobut-2-ene-... | CAS号5006-22-4 环丁基甲酰氯 | CAS号3721-95-7 环丁基甲酸 | CAS号124-38-9 二氧化碳 | CAS号4415-82-1 环丁基甲醇 | CAS号4415-73-0 1,1-二(羟甲基)环丁烷 | CAS号141232-83-9 1-methoxycarbon... | CAS号41575-94-4 卡铂 | CAS号22308-09-4 1,1-Cyclobutane... | CAS号35207-71-7 3-氯环丁烷羧酸

1-氰基环丁烷羧酸置于氢氧化钾体系中,化学反应生成 1,1-环丁基二甲酸
参考文献:Carpenter; Perkin,Journal Of The Chemical Society,1899,Vol. 75,P. 933
标题:Carpenter; Perkin,Journal Of The Chemical Society,1899,Vol. 75,P. 933

专利信息

专利号:US-2025206743-A1
优先权日:2022-03-25
标 题:Tyk2 inhibitor synthesis and intermediates thereof
发明人：MASSE CRAIG E; PHADKE AVINASH S; LAWSON JON P; LEVY STUART; YANG XIAOWEI; WU GUISHENG; FAN SHUFENG
权利人:TAKEDA PHARMACEUTICALS CO
摘要:Described herein are methods of synthesis of a tyrosine-protein kinase 2 (TYK2) inhibitor and to intermediate compounds of the synthesis and methods of making the intermediates. Also provided are pharmaceutically acceptable compositions including compounds prepared by the synthetic method and methods of treating disorders using the same.

专利号:US-2022089618-A1
优先权日:2019-01-29
标题:Solid-State Synthesis Of Precursors Of Metal-Organic Frameworks
发明人：MAJANO GERARDO J; FALKOWSKI JOSEPH M
权利人:EXXONMOBIL RES & ENG CO
摘要:Metal-organic frameworks (MOFs) are highly porous entities comprising a multidentate ligand coordinated to multiple metal atoms, typically as a coordination polymer. MOFs are usually produced from a solvent in powder form under hydrothermal or solvothermal synthesis conditions. Alternately, powder-form precursors of MOFs may be formed by milling or mulling a substantially solid mixture of a metal salt and a multidentate organic ligand, optionally in the presence of a small amount of a solvent. The powder-form precursors may then undergo heating, typically in the absence of applied shear, to produce the corresponding MOF. Mulling may be differentiated from milling at least in that mulling applies to the substantially solid mixture at a non-constant pressure and milling applies a constant pressure while forming the powder-form precursor. In some cases, mulling may promote more effective formation of the powder-form precursor compared to milling.

专利号:US-7108845-B2
优先权日:2000-03-23
标题:Methods of synthesis and use of radiolabelled platinum chemotherapeutic agents
发明人：SMITH SUZANNE V
权利人:AUSTRALIAN NUCLEAR SCIENCE TEC
摘要:There is provided a method of synthesis of a radiolabelled platinum chemotherapeutic agent comprising the steps of: converting a metal halide to a radiolabelled platinum halide wherein the radiolabel is a radioisotope of Pt; and synthesizing the radiolabelled platinum chemotherapeutic agent from the radiolabelled platinum halide.

专利号:US-6051704-A
优先权日:1996-07-22
标题:Synthesis of macrocyclic tetraamido-N ligands
发明人：GORDON-WYLIE SCOTT W; COLLINS TERRENCE J
权利人:UNIV CARNEGIE MELLON
摘要:New synthetic methods for the preparation of macrocyclic amido-N donor ligands are provided. The primary method of the present invention involves in general only two synthetic steps. In the first step, an α or β amino carboxylic acid is allowed to react with an optimal (approximately stoichiometric) amount of an activated malonate or oxalate derivative with mild heating. Upon completion of the double coupling reaction, hydrolysis of the reaction mixture yields a diamide containing intermediate (a macro linker). In the second step, stoichiometric amounts of a diamine, preferably an orthophenylene diamine, are added to the macro linker intermediate in the presence of a coupling agent and heat. This second double coupling reaction, is allowed to proceed for a period of time sufficient to produce a macrocyclic tetraamido compound. The substituent groups on the α or β amino carboxylic acid, the malonate, and the aryl diamine may all be selectively varied so that the resulting tetraamido macrocycle can be tailored to specific desired end uses. The macrocyclic tetraamide ligand may then be complexed with a metal, such as a transition metal, and preferably the middle and later transition metals, to form a robust chelate complex suitable for catalyzing oxidation reactions.

专利号:US-10737239-B2
优先权日:2015-11-27
标题 :Ultrafast high space-time-yield synthesis of metal-organic frameworks
发明人：BURCKHART JULIA; MARX STEFAN; ARNOLD LENA; HOFMANN CLAUS; Müller Ulrich
权利人:BASF SE
摘要:The invention relates to a process for the preparation of metal-organic frameworks (MOFs) in form of a homogenous powder, and a process wherein the metal-organic framework is molded into shaped bodies.

专利号:US-9951095-B2
优先权日:2014-05-16
标 题:Chromium metal organic frameworks and synthesis of metal organic frameworks
发明人：ZHOU HONG-CAI; Liu tian-fu; LIAN XIZHEN; ZOU LANFANG; FENG DAWEI
权利人:TEXAS A & M UNIV SYS
摘要:The present invention relates to monocrystalline metal organic frameworks comprising chromium ions and carboxylate ligands and the use of the same, for example their use for storing a gas. The invention also relates to methods for preparing metal organic frameworks comprising chromium, titanium or iron ions and carboxylate ligands. The methods of the invention allow such metal organic frameworks to be prepared in monocrystalline or polycrystalline forms.