CAS: 425-75-2; Ethyl Trifluoromethanesulfonate

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74427-22-8 6226-25-1 73323-80-5

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CAS号64-17-5 乙醇 | CAS号358-23-6 三氟甲磺酸酐 | CAS号2923-28-6 三氟甲烷磺酸银 | CAS号75-03-6 碘乙烷 | CAS号1493-13-6 三氟甲烷磺酸 | CAS号105-58-8 碳酸二乙酯 | CAS号60-29-7 乙醚 | CAS号68602-57-3 三氟乙酰三氟甲磺酸酯 | CAS号54509-73-8 ethene | CAS号64-67-5 硫酸二乙酯 | CAS号4423-94-3 2-乙基环己酮 | CAS号22920-59-8 PHENYL-(1-PHENY... | CAS号6137-03-7 3-乙基-2-戊酮 | CAS号589-38-8 3-己酮 | CAS号15726-15-5 3-甲基-4-庚酮 | CAS号107-87-9 2-戊酮 | CAS号620-14-4 3-乙基甲苯 | CAS号611-14-3 邻乙基甲苯 | CAS号622-96-8 4-乙基甲苯 | CAS号1493-13-6 三氟甲烷磺酸

Ethansulfonsaeure-Trifluormethansulfonsaeure-Anhydrid 反应生成 三氟甲烷磺酸乙酯
参考文献:Huthmacher K.; Koenig G.; Effenberger F.,Chem. Ber.,1975,108,No 9,2947-2954
标题:Huthmacher K.; Koenig G.; Effenberger F.,Chem. Ber.,1975,108,No 9,2947-2954

专利信息

专利号:US-11912647-B2
优先权日:2020-05-22
标 题:Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation
发明人：CRICH DAVID; HETTIKANKANAMALAGE ASIRI; HILL JARVIS
权利人:UNIV GEORGIA
摘要:In one aspect, the disclosure relates to a method for the direct synthesis of complex N,N,O-trisubstituted hydroxylamines by N—O bond formation. In another aspect, the method can successfully be employed using a wide variety of commercially available alcohols and secondary amines and enables the construction of large fragment-based libraries of trisubstituted hydroxylamines for drug discovery purposes. Also disclosed are N,N,O-trisubstituted hydroxylamines having low basicity, high stability at ambient temperatures, and an inherent lack of reactivity towards acetylating and sulfonylating enzymes that confer mutagenicity on less-substituted hydroxylamines.

专利号:WO-2015198349-A1
优先权日:2014-06-25
标 题 :A one pot synthesis of 3-substituted quinoline carboxylates and its derivatives
发明人：GADAKH SUNITA KHANDERAO; SUDALAI ARUMUGAM
权利人:COUNCIL SCIENT IND RES
摘要:The present invention provides a one pot, simple, cost effective and industrially feasible catalytic synthesis of quinolines or substituted quinolines from anilines with yield >80% yield. The present invention also discloses a process for the synthesis of oxolinic acid using quinolines with yield > 45%.

专利号:US-10927135-B2
优先权日:2017-08-03
标 题:Metal-free direct arylation of dialkyl phosphonates for the synthesis of mixed alkyl aryl phosphonates
发明人：KANG JUN YONG; HUANG HAI
权利人:THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIV OF NEVADA LAS VE
摘要:Provided herein are phosphates, thiophosphates, phosphonates, and phosphinates, methods of making same, and methods of using these compounds and methods for the generation of pharmaceutically relevant phosphate, phosphonate, and phosphinate analogs. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

专利号:US-2020354404-A1
优先权日:2019-05-09
标 题 :Peptidomimetic agents, synthesis and uses thereof
发明人：AL-ABED YOUSEF
权利人:FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
摘要:Compounds for use in synthesis of peptidomimetic agents; synthesis of peptidomimetic agents; peptidomimetic diagnostic and therapeutic agents; and uses of the compounds and peptidomimetic agents in drug discovery, diagnosis, prevention and treatment of diseases are described.

专利号:WO-2010144293-A1
优先权日:2009-06-08
标 题 :Synthesis of telcagepant and intermediates thereof
发明人：XU FENG; DESMOND RICHARD; HOERRNER R SCOTT; HUMPHREY GUY R; ITOH TETSUJI; JOURNET MICHEL; YOSHIKAWA NAOKI; ZACUTO MICHAEL J
权利人:MERCK SHARP & DOHME; XU FENG; DESMOND RICHARD; HOERRNER R SCOTT; HUMPHREY GUY R; ITOH TETSUJI; JOURNET MICHEL; YOSHIKAWA NAOKI; ZACUTO MICHAEL J
摘要:Disclosed is an efficient synthesis for the manufacture of the caprolactam intermediate (3R,6S)-3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one: Formula and salts thereof, and an efficient preparation of telcagepant using the caprolactam intermediate.

专利号:US-6417399-B1
优先权日:1997-01-14
标 题:Amelioration of neurological disorders by the administration of (2R),(3S), and/or (2S),3(S) stereoisomers of valnoctamide
发明人：BIALER MEIR; YAGEN BORIS; SPIEGELSTEIN OFER; ROEDER MICHAEL; SCHURIG VOLKER
权利人:YISSUM RES DEV CO
摘要:The present invention generally relates to the individual stereoisomers of the drug valnoctamide (a mixture of four stereoisomer kinds, VCD-valmethamide or 2-ethyl-3-methyl pentanamide) useful in treatment of neurological and psychotic disorders such as different kinds of epilepsy and affective disorders, and useful as tranquilizers and to treat pain, and to pharmaceutical compositions containing, as an active ingredient, these stereoisomers. The present invention further relates to a method for stereoselective separation and quantification of the four stereoisomers from a racemic mixture of VCD or plasma of patients treated with the racemic drug. The present invention further relates to a unique method for the synthesis of the individual stereoisomers.