CAS: 31643-49-9; 4-Nitrophthalonitrile

上下游产品

CAS号13138-53-9 4-硝基邻苯二甲酰胺 | CAS号91-15-6 邻苯二甲腈 | CAS号610-27-5 4-硝基邻苯二甲酸 | CAS号24564-72-5 1,2-BENZENEDICA... | CAS号108-24-7 乙酸酐 | CAS号106144-21-2 4-°Ctoxybenzene... | CAS号109702-53-6 4-(4-ethylpheno... | CAS号106144-19-8 4-[(2-methylpro... | CAS号51762-68-6 3-苯硫基邻苯二甲腈 | CAS号38103-06-9 双酚A二酐(BPADA) | CAS号38791-62-7 4-苯氧基邻苯二甲腈 | CAS号30757-50-7 4-羟基邻苯二甲腈 | CAS号141031-59-6 4-[2,4-bis(2-me...

4-硝基邻二甲苯置于氨体系中,230.0~400.0 °C,10.0 Kpa 条件下,以92.3%的收率获得产物4-硝基邻苯二甲腈
参考文献:一种4-硝基邻苯二甲腈的合成方法
标题:一种4-硝基邻苯二甲腈的合成方法
摘要:本发明公开了一种4‑硝基邻苯二甲腈的合成方法,该方法包括:以4‑硝基邻二甲苯,氨气和空气为原料,在催化剂存在下,于流化床反应器中反应得到4‑硝基邻苯二甲腈,其中,4‑硝基邻二甲苯,氨气和空气在混合器中混合后,进入到反应床中,与反应床中的催化剂接触反应,得到4‑硝基邻苯二甲腈.本发明所提供的4‑硝基邻苯二甲腈的合成方法工艺简单,且能实现连续化反应,生产成本低,降低三废量,可应用于工业化生产.

专利信息

专利号:US-12410140-B2
优先权日:2020-06-19
标题:Method for synthesis of roxadustat and intermediate thereof, and intermediate thereof
发明人：ZHANG YONG; WANG GUO; YANG FEI; LIU FENGWEI; ZHOU CHUNDONG; ZHANG ZITONG
权利人:JUMPCAN SHANGHAI MEDICAL TECH CO LTD
摘要:Disclosed are a method for the synthesis of roxadustat and an intermediate thereof, and an intermediate thereof. In particular, disclosed is a method for the synthesis of compound M1, the method comprising the following steps: carrying out a reaction as shown below between compound SM and compound SM-A under the action of an oxidizing agent. The method of the present invention uses cheap and easily available raw materials, has short reaction steps, produces a high yield, has simple and convenient post-treatment procedures, and is suitable for industrial production.

专利号:US-8981036-B2
优先权日:2012-08-02
标 题:Synthesis of and curing additives for phthalonitriles
发明人：KELLER TEDDY M; LASKOSKI MATTHEW
权利人:KELLER TEDDY M; LASKOSKI MATTHEW; US NAVY
摘要:A composition having a mixture of the below compounds having a mole ratio of at least 1:20. Ar 1 and Ar 2 are independently selected aromatic groups. A composition comprising phthalonitrile compounds that comprise at least 5 mol % of the first compound below. n nA method of: providing a solution of a dichloroaromatic compound having an electron-withdrawing group bound to each aromatic ring containing one of the chloride groups; a dihydroxyaromatic compound or anion thereof; an organic transition metal complex or a transition metal salt; an alkaline hydroxide base; and a solvent; and heating the solution to a temperature at which the dichloroaromatic compound and the dihydroxyaromatic compound react to form a dimetallic salt of an aromatic ether oligomer. The molar ratio of the dihydroxyaromatic compound to the dichloroaromatic compound is greater than 2:1. Water formed during the heating is concurrently distilled from the solution.

专利号:WO-2015183518-A1
优先权日:2013-03-15
标 题:Synthesis of and curing additives for phthalonitriles
发明人：KELLER TEDDY M; LASKOSKI MATTHEW; SAAB ANDREW
权利人:US GOVERNMENT; KELLER TEDDY M; LASKOSKI MATTHEW; SAAB ANDREW
摘要:A method of: providing a solution of a dichloroaromatic compound having an electron- withdrawing group bound to each aromatic ring containing one of the chloride groups; a dihydroxyaromatic compound or anion thereof; an organic transition metal complex or a transition metal salt; a base; and a solvent; and heating the solution to a temperature at which the dichloroaromatic compound and the dihydroxyaromatic compound react to form a dimetallic salt of an aromatic ether oligomer. The molar ratio of the dihydroxyaromatic compound to the dichloroaromatic compound is greater than 2: 1. Water formed during the heating is concurrently distilled from the solution. A composition having a mixture of the below compounds having a mole ratio of at least 1:20. Ar 1 and Ar 2 are independently selected aromatic groups. A composition comprising phthalonitrile compounds that comprise at least 5 mol% of the first compound below.

专利号:US-8735532-B2
优先权日:2012-08-02
标题 :Synthesis of and curing additives for phthalonitriles
发明人：KELLER TEDDY M; LASKOSKI MATTHEW; SAAB ANDREW
权利人:KELLER TEDDY M; LASKOSKI MATTHEW; SAAB ANDREW; US NAVY
摘要:A method of: providing a solution of a dichloroaromatic compound having an electron-withdrawing group bound to each aromatic ring containing one of the chloride groups; an excess of a dihydroxyaromatic compound; an organic transition metal complex or a transition metal salt; a base; and a solvent; and heating the solution to a temperature at which the dichloroaromatic compound and the dihydroxyaromatic compound react to form an aromatic ether oligomer that is a dihydroxy-terminated compound or a dimetallic salt thereof. Water formed during the heating is concurrently distilled from the solution. A method of curing a phthalonitrile monomer in the presence of an acid and a curing agent to form a phthalonitrile thermoset.

专利号:US-8859712-B2
优先权日:2012-08-02
标 题 :Synthesis of and curing additives for phthalonitriles
发明人：KELLER TEDDY M; LASKOSKI MATTHEW; SAAB ANDREW
权利人:KELLER TEDDY M; LASKOSKI MATTHEW; SAAB ANDREW; US GOVERNMENT
摘要:A method of: providing a solution of a dichloroaromatic compound having an electron-withdrawing group bound to each aromatic ring containing one of the chloride groups; a dihydroxyaromatic compound; an organic transition metal complex or a transition metal salt; a base; and a solvent; and heating the solution to a temperature at which the dichloroaromatic compound and the dihydroxyaromatic compound react to form a dimetallic salt of an aromatic ether oligomer. The molar ratio of the dihydroxyaromatic compound to the dichloroaromatic compound is greater than 2:1. Water formed during the heating is concurrently distilled from the solution.

专利号:US-2024018109-A1
优先权日:2020-06-19
标题 :Method for synthesis of roxadustat and intermediate thereof, and intermediate thereof