3-Cyano-4,6-Dimethylpyridine-2-Sulfonyl Chloride 以81%的收率获得2-氯-3-氰基-4,6-二甲基吡啶
参考文献:3-Cyano-4,6-Dimethyl-5-R-Pyridine-2-Sulfonyl Chlorides And N-Substituted Sulfonylamides Based On Them
标题:3-Cyano-4,6-Dimethyl-5-R-Pyridine-2-Sulfonyl Chlorides And N-Substituted Sulfonylamides Based On Them
摘要:3-Cyanopyridine-2-Sulfonyl Chlorides Were Synthesized By The Oxidative Chlorination Of The Respective 3-Cyanopyridine-2(1H)-2-Thiones. It Was Established That 3-Cyano-4,6-Dimethylpyridine-2-Sulfonyl Chloride Eliminates A So(2) Molecule At The Isolation Stage. N-Substituted Sulfonylamides Based On The Latter Were Obtained By The Reaction Of The Crude Sulfonyl Chloride With Amines In An Aqueous Medium.
Doi:10.1007/s10593-009-0386-4