CAS: 765-70-8; 3-Methylcyclopentane-1,2-Dione

该化合物是分子式C6H8O2的圆形二氯酮,在3位置以甲基组替代5人环形结构,该化合物因其作为有机合成中的关键中间体的作用,特别是在品味和香味化合物的生产中所发挥的作用而引起兴趣.其α二氯酮功能能够参与凝聚和循环反应,使其对构建环环形框架具有价值.甲基替代在保持再活动的同时,增强稳定性,在合成应用中提供有控制的选择性.它还研究其在制药和农用化学研究中的潜力,其结构模型有助于生物活性分子的开发.

结构式图片

相似化合物

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物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

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合成工艺路线路线简述

    📜2-甲基环戊酮置于四氯化碳,氯体系中,化学反应生成 甲基环戊烯醇酮
    参考文献:Gault; Burkhard,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1937,Vol. 205,P. 1416
    标题:Gault; Burkhard,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1937,Vol. 205,P. 1416

    海关参考信息

    专利信息


    专利号:US-2005003744-A1
    优先权日:2001-11-16
    标题 :Synthesis of chemically reactive ceria composite nanoparticles and CMP applications thereof
    发明人：FENG XIANGDONG; HER YIE-SHEIN; MAO YUN
    权利人:FERRO CORP
    摘要:The present invention provides a method of synthesizing nanosized abrasive particles and methods of using the same in chemical mechanical polishing slurry applications. The nanosized abrasive particles according to the invention are produced by hydrothermal synthesis. The crystallites of the particles include cerium atoms and atoms of metals other than cerium. In a preferred embodiment of the invention, the crystallites exhibit a cubic crystal lattice structure. The differences in electric potential between the cerium atoms and the atoms of metals other than cerium facilitate the polishing of films without the need for chemical oxidizers.

    专利号:US-7666239-B2
    优先权日:2001-11-16
    标题:Hydrothermal synthesis of cerium-titanium oxide for use in CMP
    发明人：FENG XIANGDONG; HER YIE-SHEIN; YANG YI
    权利人:FERRO CORP
    摘要:The present invention provides a method of synthesizing abrasive particles and methods of using the same in chemical mechanical polishing slurry applications. The nanosized abrasive particles according to the invention are produced by hydrothermal synthesis using an insoluble source of cerium. The crystallites of the particles include cerium ions and titanium ions.

    专利号:US-3962354-A
    优先权日:1970-06-24
    标题 :Synthesis of cis-3-hexen-1-ol
    发明人：DAHILL JR ROBERT T
    权利人:GIVAUDAN CORP
    摘要:There is provided a novel method of preparing the highly desired odorant cis-3-hexen-1-ol from alkyl phenyl ethers. The method comprises Birch reduction of the alkyl phenyl ether, sequentially followed by oxidative ring cleavage and reduction.

    专利号:US-4168280-A
    优先权日:1978-05-19
    标题 :Method for synthesis of 2-hydroxy-3-methyl cyclopent-2-ene-1-one
    发明人：NASH WILLIAM D
    权利人:EL PASO PRODUCTS CO
    摘要:The known compound 2-hydroxy-3-methyl cyclopent-2-ene-1-one, used as a flavor imparting agent and commonly called maple lactone, is synthesized by a modified acyloin condensation of esters of 2-methyl glutaric acid in which oxygen is introduced in a specific manner to the reaction system.

    专利号:US-4359586-A
    优先权日:1981-02-12
    标 题:Synthesis 2-alkyl cyclopentenolones
    发明人：HO TSE-LOK; LIU SHING-HOU
    权利人:SCM CORP
    摘要:2-Hydroxy-3-methylcyclopent-2-en-1-one was synthesized in a five-step synthesis starting from 2-methyl-1,3-butadiene. Novel intermediate steps include the hot tube isomerization of 1,1-dihalo-2-methyl-2-vinylcyclopropane to give 1-methyl-4,4-dihalocyclopent-1-ene, hydrolysis to 3-methyl-2-cyclopenten-1-one, epoxidation of the latter using a phase transfer catalyst, followed by catalyzed isomerization to produce 2-hydroxy-3-methylcyclopent-2-en-1-one in high overall yield.

    专利号:US-2006112649-A1
    优先权日:2001-11-16
    标题:Hydrothermal synthesis of cerium-titanium oxide for use in CMP

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    主要参考文献

    [参考文献]: Ae Ra Kim, Et Al. Selective Peroxynitrite Scavenging Activity Of 3-Methyl-1,2-Cyclopentanedione From Coffee Extract. J Pharm Pharmacol. 2002 Oct;54(10):1385-92.
    [参考文献]: Bruna R Toledo, Et Al. A Chemometric Approach Toward The Detection And Quantification Of Coffee Adulteration By Solid-Phase Microextraction Using Polymeric Ionic Liquid Sorbent Coatings. J Chromatogr A. 2014 Jun 13:1346:1-7.
    [参考文献]: Bryson W Katona, Et Al. Enantiomeric Deoxycholic Acid: Total Synthesis, Characterization, And Preliminary Toxicity Toward Colon Cancer Cell Lines. J Org Chem. 2007 Nov 23;72(24):9298-307.
    [参考文献]: Jae Heun Chung, Et Al. 3-Methyl-1,2-Cyclopentanedione Down-Regulates Age-Related Nf-Kappab Signaling Cascade. J Agric Food Chem. 2007 Aug 8;55(16):6787-92.
    [参考文献]: M Mozaffarieh, Et Al. The Potential Value Of Natural Antioxidative Treatment In Glaucoma. Surv Ophthalmol. 2008 Sep-Oct;53(5):479-505.

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    参考文献:10.1007/978-981-99-0546-1_2
    摘要:Tian Z, Mbayachi VB, Dai W, Khalil M, Ayejoto DA. Gas Chromatography/Mass Spectrometry. 2023. In: Advanced Diagnostics in Combustion Science.
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    摘要:Clemente-Castro S, Palma A, Ruiz-Montoya M, Giráldez I, Díaz MJ. Optimizing pyrolysis parameters and product analysis of a fluidized bed pilot plant for Leucaena leucocephala biomass. Environ Sci Eur. 2023 Oct 31;35(1). doi: 10.1186/s12302-023-00800-w.
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    摘要:Morelle J, Jeanneau L, Laverman AM. Organic Carbon Quality Impacts Benthic Microbial Nitrate Reduction. Wetlands. 2023 Nov 03;43(8). doi: 10.1007/s13157-023-01747-7.
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