CAS: 72093-07-3; 5-Chloro-2-Methylpyridine

相似化合物

72093-03-9 1196153-33-9 1881292-44-9

上下游产品

CAS号16110-09-1 2,5-二氯吡啶 | CAS号594-27-4 四甲基锡 | CAS号1199-48-0 4,5-dichloro-2-... | CAS号70788-54-4 2,3,4-trichloro... | CAS号43077-77-6 4,5-二羟基-2-羧酸吡啶 | CAS号21684-59-3 6-甲基吡啶-3-甲酸乙酯 | CAS号80287-53-2 3-氨基-6-甲基吡啶 | CAS号6960-22-1 6-甲基烟酰胺 | CAS号197079-25-7 6-甲基吡啶-3-碳酰肼 | CAS号64038-04-6 6-Methyl-3-pyri... | CAS号605681-01-4 2-溴甲基-5-氯吡啶 | CAS号38956-79-5 3-肼基-6-甲基哒嗪 | CAS号86873-60-1 5-氯吡啶-2-羧酸 | CAS号128073-03-0 5-氯吡啶-2-酰氯 | CAS号132308-19-1 5-氯吡啶-2-羧酸甲酯 | CAS号907208-89-3 4-(5-甲基吡啶-2-基)哌... | CAS号97944-39-3 5-Chloro-2-meth...

6-甲基-3-吡啶羰基叠氮化物置于盐酸,氢氧化钾,Potassium Nitrite体系中,化学反应生成 5-氯-3-甲基吡啶
参考文献:Graf,Journal Fur Praktische Chemie (Leipzig 1954),1932,Vol. <2> 133,P. 36,49
标题:Graf,Journal Fur Praktische Chemie (Leipzig 1954),1932,Vol. <2> 133,P. 36,49

专利信息

专利号:US-6822093-B2
优先权日:2000-05-23
标题 :Synthesis of heteroarylamine intermediate compounds
发明人：SONG JINHUA J; YEE NATHAN K
权利人:BOEHRINGER INGELHEIM PHARMA
摘要:Disclosed are novel 2-(5-halopyridyl) and 2-(5-halopyrimidinyl) magnesium halides, processes of making and their use in the efficient synthesis in their respective 5-halo-2-substituted pyridines and pyrimidines.

专利号:US-9676783-B2
优先权日:2008-10-22
标 题:Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds
发明人：HAAS JULIA; ANDREWS STEVEN W; JIANG YUTONG; ZHANG GAN
权利人:ARRAY BIOPHARMA INC
摘要:Compounds useful in the synthesis of compounds for treating pain, cancer, inflammation, neurodegenerative disease or Typanosoma cruzi infection in a mammal.

专利号:US-8853410-B2
优先权日:2009-04-30
标 题:Process for preparing substituted isoxazoline compounds and their precursors
发明人：RACK MICHAEL; KOERBER KARSTEN; KAISER FLORIAN
权利人:RACK MICHAEL; KOERBER KARSTEN; KAISER FLORIAN; BASF SE
摘要:The present invention relates to a new method of preparing halogenated styrene compounds of formula (VIII) n nwhich are precursors in the process of synthesis of substituted isoxazoline compounds of formula (I)n n nwherein R 1 to R 5 , R 8 and R 9 are described as in the description.n n The present invention relates further to the synthesis of compounds of formula (I) starting from acetophenones. The desired styrenes of formula are prepared from the appropriate substituted acetophenone. Asides bromo anilines react with formoxime. Obtained oximes undergo a cycloaddition with the styrenes and give isoxazolines. Compounds of formula (I) can then be prepared in a palladium catalyzed carbonylative amination reaction of the isoxazolines.

专利号:US-2003135046-A1
优先权日:2000-05-23
标题 :Synthesis of heteroarylamine intermediate compounds

专利号:US-2003219832-A1
优先权日:1996-03-11
标 题 :Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
发明人：KLEIN ELLIOTT S; STANDEVEN ANDREW M; NAGPAL SUNIL; CHANDRARATNA ROSHANTHA A
摘要:Aryl-substituted and aryl and (3-oxo-1-propenly)-substituted benzopyran, benzothiopyran, 1,2-dihydroquinoline, and 5,6-dihydronaphthalene derivatives have retinoid negative hormone and/or antagonist-like biological activities. The invented RAR antagonists can be administered to mammals, including humans, for the purpose of preventing or diminishing action of RAR agonists on the bound receptor sites. Specifically, the RAR agonists are administered or coadministered with retinoid drugs to prevent or ameliorate toxicity or side effects caused by retinoids or vitamin A or vitamin A precursors. The retinoid negative hormones can be used to potentiate the activities of other retinoids and nuclear receptor agonists. For example, the retinoid negative hormone called AGN 193109 effectively increased the effectiveness of other retinoids and steroid hormones in in vitro transactivation assays. Additionally, transactivation assays can be used to identify compounds having negative hormone activity. These assays are based on the ability of negative hormones to down-regulate the activity of chimeric retinoid receptors engineered to possess a constitutive transcription activator domain.

专利号:US-2001053850-A1
优先权日:2000-05-23
标题 :Novel synthesis of heteroarylamine intermediate compounds