CAS: 54910-89-3; Fluoxetine

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CAS号42142-52-9 N-甲基-3-苯基-3-羟基丙胺 | CAS号98-56-6 4-氯三氟甲苯 | CAS号204704-95-0 N-甲基-N-[3-苯基-3-... | CAS号402-45-9 4-(三氟甲基)苯酚 | CAS号57226-06-9 methyl-[3-pheny... | CAS号936-59-4 3-氯代苯丙酮 | CAS号56296-78-7 盐酸氟西汀 | CAS号18776-12-0 3-氯-1-苯基丙醇 | CAS号62872-58-6 3-iodo-1-phenyl... | CAS号56296-78-7 盐酸氟西汀 | CAS号114247-09-5 R-氟西汀

Phenyl N-Methyl-3-(P-Trifluoromethylphenoxy)-3-Phenylpropyl-Amine-N-Carboxylate置于甲基氯化镁,水,氯化铵体系中,用 四氢呋喃,甲苯 作为反应溶剂,化学反应生成 氟西汀
参考文献: Method For The Preparation Of N-Methyl-Aryloxy-Propanamine Derivatives[fr] Procédé De Préparation De Dérivés De N-Méthyl-Aryloxy-Propanamine
标题: Method For The Preparation Of N-Methyl-Aryloxy-Propanamine Derivatives[fr] Procédé De Préparation De Dérivés De N-Méthyl-Aryloxy-Propanamine

专利信息

专利号:US-9353057-B2
优先权日:2003-12-30
标 题:Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
发明人：GALLOP MARK A; DAI XUEDONG; SCHEUERMAN RANDALL A; RAILLARD STEPHEN P; MANTHATI SURESH K; YAO FENMEI; PHAN THU; LUDWIKOW MARIA; PENG GE; BHAT SEEMA
权利人:XENOPORT INC
摘要:Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.

专利号:US-7294486-B2
优先权日:2001-09-05
标 题:Enzymatic process for the synthesis of organo-fluorine compounds
发明人：O'HAGAN DAVID; SCHAFFRATH CHRISTOPH
权利人:UNIV ST ANDREWS
摘要:There is described a process for the synthesis of a fluoronucleoside compound, said process comprising mixing a substrate and an enzyme from Streptomyces cattelya as catalyst. The process may be used to produce an 18 F labelled fluoronucleoside compound. There is also described an enzyme derived from Streptomyces cattelya which has the capacity to catalyse the synthesis of a fluoronucleoside compound.

专利号:US-8889897-B2
优先权日:2011-12-23
标 题:Electrocarboxylation synthesis for obtaining intermediates useful for the synthesis of SPAN derivatives
发明人：OSSO J ORIOL; VEGA LOURDES F; GALLARDO ILLUMINADO; GUIRADO GONZALO; GOMEZ ANA BELEN; RECHE FRANCISCA IRENE
权利人:AIR PROD & CHEM
摘要:The present invention relates to a process for obtaining a compound of formula (1), (2) or (3) by means of a electrocarboxylation with CO 2 . The present invention also relates to the new intermediates (1) and (2). The present invention further relates to the use of intermediates (1) and (2) as starting materials for the synthesis of SPAN derivatives.

专利号:US-2003083352-A1
优先权日:2000-07-31
标 题 :Synthesis of imidazole intermediates
发明人：HELAL CHRISTOPHER J
权利人:PFIZER
摘要:The invention provides a method for synthesis of compounds of formula n n n wherein R 1 and R 19 are as defined. Compounds of formula 12 are useful as intermediates for synthesizing compounds having pharmacological activity inhibiting cdk5, cdk2, and GSK-3.

专利号:US-2004072282-A1
优先权日:2002-10-15
标题:Synthesis of membrane proteins
发明人：GUARNIERI FRANK; KULP JOHN; CHIANG WILLIAM
权利人:SARNOFF CORP
摘要:Methods for chemical ligation and synthesis of peptides and polypeptides including membrane polypeptides and hydrophobic peptides and polypeptides or membrane polypeptide domains in a multiphase solvent mixture comprising at least two component solvents; compositions produced using these methods and assays performed using these compositions.

专利号:US-8367868-B2
优先权日:2006-10-16
标题:Process for the synthesis of aryloxypropylamine and heteroaryloxypropylamine
发明人：BERTOLINI GIORGIO; VERZOLA BARBARA; VERGANI DOMENICO
权利人:ARCHIMICA SRL; BERTOLINI GIORGIO; VERZOLA BARBARA; VERGANI DOMENICO
摘要:The present invention relates to a process for the synthesis of aryloxypropylamine and heteroaryloxypropylamine of formula I: n nwhere: A is aryl or heteroaryl, where the aryl is preferably a phenyl, optionally substituted, selected from benzyl and tolyl and the heteroaryl is preferably thiophenyl; Y is an aryl, preferably phenyl, a substituted phenyl or a naphthyl, where the substituted phenyl is preferably selected from tolyl, trihalomethyltolyl and alkoxytolyl, starting from a suitable amino alcohol of formula II: