CAS: 4393-16-2; 4-(Methylsulfonyl)Benzylamine

该化合物是一种有机化合物,其特征是附于一个苯环的甲基硫酰集团,以及一个甲基苯胺功能集团,该化合物通常具有芳香和含膜功能的特性,这些功能可影响其溶性,再活性以及与生物系统的互动.甲基硫酰胺集团有助于其极性,有可能提高极地溶剂的溶性.该聚氨酯集团的存在表明,它可以作为质质的矿,在各种化学环境中可传播基本性并影响其行为.这些化合物可能具有潜在的生物活动,包括抗微生物或抗炎特性,因此对医药化学具有兴趣.此外,4-(甲基硫酰)苯的结构性特征可能允许进行各种合成改造,使其在有机合成中成为一个多用途建筑块.与任何化学物质一样,在与该化合物一起工作时,应当考虑安全数据和处理预防措施.

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CAS号98593-51-2 4-(甲磺酰基)苄胺盐酸盐 | CAS号5661-48-3 (1Z)-1-[[2-(5-p... | CAS号22821-80-3 4'-甲基磺酰乙酰苯胺 | CAS号22821-76-7 4-甲砜基苯腈 | CAS号628297-98-3 4-(acetylamino-... | CAS号28073-51-0 4-(乙酰氨基甲基)苯磺酰氯 | CAS号5470-49-5 4-甲磺酰基苯胺 | CAS号710-24-7 对乙酰氨基苯亚磺酸 | CAS号3185-99-7 对甲砜基甲苯 | CAS号694480-96-1 N-B°C-4-甲砜基苄胺 | CAS号904311-34-8 4-氨基-5-氰基-6-乙氧基... | CAS号5661-48-3 (1Z)-1-[[2-(5-p...

合成工艺路线路线简述

    📜4-(甲砜基)苄胺盐酸盐置于potassium Carbonate体系中,用 水 作为反应溶剂,化学反应生成 4-甲基苯硫酸氢氯酸嘧啶
    参考文献:Methods And Compositions For Treating Amyloid-Related Diseases
    标题:Methods And Compositions For Treating Amyloid-Related Diseases
    摘要:描述了用于治疗或预防与淀粉样蛋白相关疾病的方法,化合物,药物组合物和试剂盒.

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    专利信息


    专利号:US-6906046-B2
    优先权日:2000-12-22
    标题 :Pharmaceutical uses and synthesis of benzobicyclooctanes
    发明人:JACKSON RANDY W; DARWISH IHAB; BAUGHMAN TED A; HOWBERT J JEFFRY
    权利人:CELLTECH R & D INC
    摘要:Benzobicyclooctane compounds, their use in inhibiting cellular events involving TNF-α and IL-8, and in the treatment of inflammation events in general; a combinatorial library of diverse bicyclooctanes and process for their synthesis as a library and as individual compounds.

    专利号:US-9908876-B2
    优先权日:2009-11-05
    标 题:Imidazo [1,2-a]pyridine compounds, synthesis thereof, and methods of using same
    发明人:MILLER MARVIN J; MORASKI GARRETT C; MARKLEY LOWELL D; DAVIS GEORGE E
    权利人:UNIV NOTRE DAME DU LAC
    摘要:Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to imidazopyridine compounds, synthesis thereof, and methods of using same. Disclosed herein are various imidazo[1,2-a]pyhdine compounds and methods of using the novel compounds to treat or prevent tuberculosis in a subject or to inhibit fungal growth on plant species. Other embodiments include methods of synthesizing imidazo[1,2-a]pyridine compounds, such as the disclosed imidazo[1,2-a]pyridine compounds.

    专利号:US-9856218-B2
    优先权日:2013-03-15
    标题:Inhibitors of PRMT5 and methods of their use
    发明人:BAIOCCHI ROBERT A; LI CHENGLONG; LAI HONGSHAN; SIF SAID
    权利人:OHIO STATE INNOVATION FOUNDATION
    摘要:In one aspect, the invention relates to PRMT5 inhibitors, including optionally substituted N-alkyl-9H-carbazole analogs, derivatives thereof, and related compounds; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders of uncontrolled cellular proliferation and benign hematologic diseases using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

    专利号:TW-I516474-B
    优先权日:2013-05-27
    标 题 :Synthesis of good ginger compounds and their analogues

    专利号:US-2003069305-A1
    优先权日:2000-12-22
    标题:Pharmaceutical uses and synthesis of benzobicyclooctanes

    专利号:TW-201512167-A
    优先权日:2013-05-27
    标题 :Synthesis of good ginger compounds and their analogues

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    合成参考文献


    参考文献:10.1023/a:1009696618386
    摘要:Slade RM, Phillips MA, Berger JG. Application of an almost traceless linker in the synthesis of 2-alkylthiobenzimidazole combinatorial libraries. Mol Divers. 1998;4(4):215–9. doi: 10.1023/a:1009696618386.
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