CAS: 37526-59-3; 2-(Trifluoromethoxy)Benzenesulfonamide

上下游产品

CAS号103008-51-1 2-(三氟甲氧基)苯磺酰氯 | CAS号1535-75-7 2-三氟甲氧基苯胺 | CAS号99722-81-3 2-(三氟甲氧基)苯磺酰异氰酸酯

2-(三氟甲氧基)苯磺酰氯置于ammonium Hydroxide体系中,用 乙腈 用作溶剂,化学反应 1.0H,反应生成2-(三氟甲氧基)苯磺酰胺
参考文献:Design And Synthesis Of Triazolopyrimidine Acylsulfonamides As Novel Anti-Mycobacterial Leads Acting Through Inhibition Of Acetohydroxyacid Synthase
标题:Design And Synthesis Of Triazolopyrimidine Acylsulfonamides As Novel Anti-Mycobacterial Leads Acting Through Inhibition Of Acetohydroxyacid Synthase
摘要:Novel Triazolopyrimidine Acylsulfonamides Class Of Antimycobacterial Agents,Which Are Mycobacterial Acetohydroxyacid Synthase (Ahas) Inhibitors Were Designed By Hybridization Of Known Ahas Inhibitors Such As Sulfonyl Urea And Triazolopyrimidine Sulfonamides. This Letter Describes The Synthesis And Sar Studies Of This Class Of Molecules By Variation Of Two Parts Of The Molecule,The Phenyl And Triazolopyrimidine Rings. Sar Study Describes Optimisation Of Enzyme Potency,Whole Cell Potency And Evidence Of Mechanism Of Action. (C) 2014 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Bmcl.2014.02.054

专利信息

专利号:WO-2021062168-A1
优先权日:2019-09-25
标 题 :Synthetic sphingolipid inspired molecules with heteroaromatic appendages, methods of their synthesis and methods of treatment
发明人：EDINGER AIMEE; HANESSIAN STEPHEN
权利人:UNIV CALIFORNIA; UNIV MONTREAL
摘要:Small molecules compounds and methods of their synthesis are provided. Formulations and medicaments are also provided that are directed to the treatment of disease, such as, for example, neoplasms, cancers, and other diseases. Therapeutics are also provided containing a therapeutically effective dose of one or more small molecule compounds, present either as pharmaceutically effective salt or in pure form, including, but not limited to, formulations for oral, intravenous, or intramuscular administration.

专利号:WO-2017199033-A1
优先权日:2016-05-18
标题:Intermediates for the synthesis of bile acid derivatives, in particular of obeticholic acid

专利号:EP-3458469-A1
优先权日:2016-05-18
标题:Intermediates for the synthesis of bile acid derivatives, in particular of obeticholic acid