CAS: 3691-21-2; 4-Hexahydroazepin-1-Yl-2,2-Diphenyl-Butyric Acid Amide

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    4-(1-氮杂环庚基)-2,2-二苯基丁腈 4-Hexahydroazepin-1-Yl-2,2-Diphenyl-Butyronitrile 83898-29-7

    合成工艺路线路线简述

      📜二苯乙腈置于硫酸,Sodium Amide,苯体系中,化学反应生成 六氢-Alpha,Alpha-二苯基-1H-氮杂卓-1-丁酰胺
      参考文献:Janssen Et Al.,Journal Of Medicinal And Pharmaceutical Chemistry,1959,Vol. 1,P. 187,189
      标题:Janssen Et Al.,Journal Of Medicinal And Pharmaceutical Chemistry,1959,Vol. 1,P. 187,189

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      专利号:US-9982006-B2
      优先权日:2014-08-21
      标题:2′-chloro aminopyrimidinone and pyrimidine dione nucleosides
      发明人:CLARKE MICHAEL O'NEIL HANRAHAN; MACKMAN RICHARD L; SIEGEL DUSTIN
      权利人:GILEAD SCIENCES INC
      摘要:Provided herein are formulations, methods and substituted 2′-chloro aminopyrimidinone and pyrimidine dione compounds of Formula (I) for treating Pneumovirinae virus infections, including respiratory syncytial virus infections, as well as methods and intermediates for synthesis of substituted 2′-chloro aminopyrimidinone and pyrimidine dione compounds.

      专利号:US-9828388-B2
      优先权日:2014-07-28
      标题:Thieno[3,2-d]pyrimidine, furo[3,2-d]pyrimidine, and pyrrolo[3,2-D]pyrimidines useful for treating respiratory syncitial virus infections
      发明人:CLARKE MICHAEL O'NEIL HANRAHAN; MACKMAN RICHARD L; SIEGEL DUSTIN
      权利人:GILEAD SCIENCES INC
      摘要:Provided herein are formulations, methods and substituted thieno[3,2-d]pyrimidine, furo[3,2-d]pyrimidine, and pyrrolo[3,2-d]pyrimidine compounds of Formula (I) for treating Pneumovirinae virus infections, including respiratory syncytial virus infections, as well as methods and intermediates for synthesis of substituted thieno[3,2-d]pyrimidine, furo[3,2-d]pyrimidine, and pyrrolo[3,2-d]pyrimidine compounds.

      专利号:US-9701682-B2
      优先权日:2013-11-11
      标题:Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections
      发明人:CLARKE MICHAEL O'NEIL HANRAHAN; DOERFFLER EDWARD; MACKMAN RICHARD L; SIEGEL DUSTIN
      权利人:GILEAD SCIENCES INC
      摘要:Provided herein are formulations, methods and substituted tetrahydrofuranyl-pyrrolo[1,2-f][1,2,4]triazine-4-amine compounds of Formula (I) for treating Pneumovirinae virus infections, including respiratory syncytial virus infections, as well as methods and intermediates for synthesis of tetrahydrofuranyl-pyrrolo[1,2-f][1,2,4]triazine-4-amine compounds.

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      ✅ COA系统入驻 | 共享模式

      主要参考文献

      1. Kalanur SS, Seetharamappa J, Prashanth SN. Interaction of an antidepressant buzepide methiodide with DNA immobilized on the glassy carbon electrode. Colloids Surf B Biointerfaces. 2011 Feb 1;82(2):438-42. doi: 10.1016/j.colsurfb.2010.09.017. Epub 2010 Sep 29.
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