CAS: 34780-29-5; Ethyl 3-Oxopropanoate

上下游产品

CAS号57042-08-7 反-3-己烯酸二甲基酯 | CAS号10601-80-6 3,3-二乙氧基丙酸乙酯 | CAS号623-47-2 丙炔酸乙酯 | CAS号141-78-6 乙酸乙酯 | CAS号109-94-4 甲酸乙酯 | CAS号105-56-6 氰乙酸乙酯 | CAS号107-31-3 甲酸甲酯 | CAS号81077-09-0 2-diazo-3-hydro... | CAS号94691-90-4 1,5-Dioxaspiro[... | CAS号4105-92-4 1,3,5-苯三羧酸三乙酯 | CAS号92-61-5 东莨菪内酯； 莨菪亭 | CAS号924-99-2 3-(二甲氨基)丙烯酸乙酯 | CAS号93-35-6 伞形花内酯； 7-羟基香豆素 | CAS号299397-03-8 2-(1-羟基乙基)嘧啶-4(3H)-酮 | CAS号27772-62-9 2-甲酰基丙酸乙酯 | CAS号89793-12-4 2-氯嘧啶-5-羧酸乙酯 | CAS号19875-04-8 2-甲基-4-羟基嘧啶 | CAS号885-94-9 1-苯基-1H-吡唑-4-羧酸乙酯 | CAS号614-98-2 3-呋喃羧酸乙酯

2-Diazo-3-Hydroxypropanoic Acid Ethyl Ester置于rhodium(II) Acetate Dimer体系中,用 二氯甲烷 用作溶剂,化学反应生成3-氧代丙酸乙酯
参考文献:Catalyzed Insertion Reactions Of Substituted α-Diazoesters. A New Synthesis Of Cis-Enoates
标题:Catalyzed Insertion Reactions Of Substituted α-Diazoesters. A New Synthesis Of Cis-Enoates
摘要:
Doi:10.1016/s0040-4039(01)82093-1

专利信息

专利号:WO-2012100419-A1
优先权日:2011-01-26
标 题 :Process for synthesis of 3-(n,n-disubstituted-amino)-2- substituted acrylate
发明人：GU HAINING; LI XIAOLING; ZHANG PENGFEI; ZHANG XIKUN; CHEN LIANG
权利人:HANGZHOU GREAT FOREST BIOMEDICAL LTD; GU HAINING; LI XIAOLING; ZHANG PENGFEI; ZHANG XIKUN; CHEN LIANG
摘要:Disclosed is a process for synthesis of 3-(N,N-disubstituted-amino)-2-substituted acrylate, which comprises carrying out amine-substitution reaction and elimination reaction for 2-substituted formylacetate alkali metal salt represented by formula (III) and amine complex represented by formula (II) in organic solvent 1 to obtain 3-(N,N-disubstituted-amino)-2-substituted acrylate represented by formula (I). The process uses N,N-disubstituted amine and carbon dioxide, or a liquid complex obtained by N,N-disubstituted amine and carbon dioxide as raw material, thereby it doesn't produce a side product influencing environment. The process has the advantages of reacting simply and operating easily.

专利号:US-8742118-B2
优先权日:2011-10-27
标题 :Methods for preparing intermediates of perampanel
发明人：FONTANA FRANCESCO; STABILE PAOLO
权利人:F I S —FABBRICA ITALIANA SINT S P A
摘要:Methods for the synthesis of 2-alkoxy-5-(pyridin-2-yl)pyridine of formula I n nor salts thereof are provided.

专利号:US-4171439-A
优先权日:1975-04-11
标 题 :Antibacterial analogs of isocephalosporins
发明人：CONWAY TERRY T; LIM GARY M F; MENARD MARCEL
权利人:BRISTOL MYERS CO
摘要:There is described the stereoselective total synthesis of novel DELTA 2,3-1,4-morpholine-2-carboxylic acids possessing a fused beta -lactam ring in the 1,6-position and carrying a substituent cis to carbon 5 in the 7-position of the fused ring system represented by the general formula I wherein Z is halo or hydroxyl and X is acylamino. Also included in the invention are compounds of the above formula in which the carboxyl group at the 2-position is protected as by an easily cleavable ester group and salts of both the free acids and carboxyl-protected compounds. The compounds are potent antibacterial agents.

专利号:US-5852180-A
优先权日:1997-11-17
标题:Chemical synthesis of 6-O-alkyl erythromycin A
发明人：PATEL HEMANTKUMAR H
权利人:ABBOTT LAB
摘要:A process of preparing 6-O-alkyl erythromycin A is provided. The process includes the steps of protecting the oxime hydroxyl of 9-oxime erythromycin A with a benzoyl protecting group, protecting the 2'-hydroxyl group and optionally the 4'-hydroxyl group with an O-protecting group, alkylating the 6-hydroxyl, removing the benzoyl and O-protecting groups and deoximating the 9-oxime.

专利号:US-7384964-B2
优先权日:2002-08-23
标题:Synthesis of epothilones, intermediates thereto, analogues and uses thereof
发明人：DANISHEFSKY SAMUEL J; RIVKIN ALEXEY; YOSHIMURA FUMIHIKO; CHOU TING-CHAO; GABARDA ANA E; DONG HUAJIN; WU KAIDA; MOORE MALCOLM A S; DORN DAVID
权利人:SLOAN KETTERING INST CANCER
摘要:The present invention provides compounds of formula (I): n nas described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).

专利号:US-9527855-B2
优先权日:2011-06-29
标题:Process for preparing chiral dipeptidyl peptidase-IV inhibitors
发明人：ZACUTO MICHAEL J; DUNN ROBERT F; MOMENT AARON J; JANEY JACOB M; LIEBERMAN DAVID; SHEEN FAYE; BREMEYER NADINE; SCOTT JEREMY; KUETHE JEFFREY T; TAN LUSHI; CHEN QINGHAO
权利人:MERCK SHARP & DOHME; MERCK SHARP & DOHME
摘要:A process for the preparation of pyrazolopyrolidines of structural formula I: n nand W isn n nor P, wherein in P is an amine protecting group. These compounds are useful in the synthesis of dipeptidyl peptidase-IV inhibitors for the treatment of Type 2 diabetes. Also provided are useful intermediates obtained from the process.