CAS: 2232-08-8; 1-(P-Toluenesulfonyl)Imidazole

相似化合物

1546-79-8 15469-97-3 288-32-4

上下游产品

CAS号288-32-4 咪唑 | CAS号98-59-9 对甲苯磺酰氯(PTSC) | CAS号536-57-2 对甲苯亚磺酸 | CAS号38028-98-7 N-(p-tolylsulfo... | CAS号18156-74-6 三甲基硅咪唑(TSIM) | CAS号75-89-8 三氟乙醇 | CAS号25370-91-6 N-benzyl-N'-(4-... | CAS号1153-45-3 4-甲基苯磺酸-4-硝基苯酯 | CAS号31271-90-6 N-(对甲苯磺酰)吲哚 | CAS号288-32-4 咪唑 | CAS号21230-07-9 N-异丙基-4-甲基苯磺酰胺 | CAS号14316-14-4 N-(2-羟乙基)-4-甲基苯磺酰胺 | CAS号1907-65-9 N-丁基对甲苯磺酰胺 | CAS号1080-44-0 N-对甲苯磺酰甘氨酸 | CAS号25700-14-5 2-咪唑-1-吡啶 | CAS号84216-71-7 单-2-O-(对甲苯磺酰)-β... | CAS号97227-32-2 单-2-O-(对甲苯磺酰)-γ-环糊精

咪唑,对甲苯磺酰氯置于sodium Hydride体系中,用 四氢呋喃 用作溶剂,化学反应 14.17H,反应生成1-对甲基苯磺酰咪唑
参考文献:电子转移光氧化还原催化:氮杂杂芳环光活化还原脱磺酰化的发展.
标题:电子转移光氧化还原催化:氮杂杂芳环光活化还原脱磺酰化的发展.
摘要:在这里,我们报告通过光致电子转移和氢原子转移氮杂杂芳环脱磺酰的协议.该通用方案具有广泛的底物范围,并且具有中等至非常好的收率.该方法的实用性通过同时包含脂族和芳族磺酰胺的分子的化学选择性去磺酰化来证明.
Doi:10.1002/adsc.202000578

专利信息

专利号:US-2005272934-A1
优先权日:2004-06-01
标题 :Process for the synthesis of thalidomide
发明人：ALPEGIANI MARCO; MAZZONI ANDREA; VERGANI DOMENICO; CABRI WALTER
权利人:ANTIBIOTICOS SPA
摘要:The invention relates to a process for the preparation of thalidomide (I) n n ncomprising the reaction between glutamine (II) n nand a phthaloylating agent, preferably phthalic anhydride, to give N-phthaloyl-glutamine, which is directly transformed in thalidomide.

专利号:EP-1602654-A1
优先权日:2004-06-01
标题 :Process for the synthesis of thalidomide

专利号:US-7122549-B2
优先权日:2000-11-03
标题:Saframycins, analogues and uses thereof
发明人：MYERS ANDREW G; PLOWRIGHT ALLEYN T
权利人:HARVARD COLLEGE
摘要:In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel compounds of general formula (I), and methods for the synthesis thereof. n n n n n n n n n n In another aspect, the present invention provides pharmaceutical compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier. In yet another aspect, the present invention provides methods for treating cancer comprising administering a therapeutically effective amount of a compound of formula (I) to a subject in need thereof.