CAS: 190079-18-6; 1-Deoxy-D-Xylulose 5-Phosphate

上下游产品

CAS号113-24-6 丙酮酸钠 | CAS号57044-25-4 (|R|)-(+)-缩水甘油 | CAS号102783-56-2 二羟基丙酮磷酸酯二锂盐 | CAS号591-57-1 甘油醛3-磷酸 | CAS号57-60-3 pyruvate | CAS号127-17-3 丙酮酸

📜(3S,4R)-5-<(Triisopropylsilyl)Oxy>-3,4-(Isopropylidenedioxy)Pentan-2-One置于2,6-二甲基吡啶,盐酸,三甲基溴硅烷,四丁基氟化铵,四氯化碲,对甲苯磺酸体系中,用 四氢呋喃,二氯甲烷,苯 用作溶剂,化学反应 13.0H,反应生成Dxp 钠盐
参考文献:Synthesis Of 1-Deoxy-D-Xylulose And 1-Deoxy-D-Xylulose-5-Phosphate
标题:Synthesis Of 1-Deoxy-D-Xylulose And 1-Deoxy-D-Xylulose-5-Phosphate
摘要:1-Deoxy-D-Xylulose (4) And The Corresponding 5-Phosphate (5) Are Substrates For The First Pathway-Specific Enzymes In The Biosynthesis Of Thiamine Diphosphate (Vitamin B-1),Pyridoxol Phosphate (Vitamin B-6),And The Nonmevalonate Family Of Isoprenoid Compounds Recently Discovered In Bacteria And Plant Chloroplasts. Both 4 And 5 Were Synthesized From Commercially Available (-)-2,3-O-Isopropylidene-D-Threitol (10). The Protected Tetraol Was Converted To (-)-3,4-O-Isopropylidene-5-Triisopropylsilyl-1-Deoxy-D-Xylulose (14) In Four Steps. Treatment Of 14 With Acetic Acid Gave 4 In An Overall Yield Of 69%. The Corresponding 5-Phosphate Was Obtained By Protection The Carbonyl Group In 14,Removal Of The Triisopropylsilyl Moiety,And Treatment Of The Resulting Alcohol With Trimethyl Phosphite/tecl4,Trimethylsilyl Bromide,Water,And Hcl In Successive Steps To Give 5 In 58% Overall Yield From 10.
Doi:10.1021/jo981966K

专利信息

专利号:US-11046978-B2
优先权日:2016-03-16
标 题:Synthesis of isoprenoids and derivatives
发明人：GONZALEZ RAMON; CLOMBURG JAMES M; CHEONG SEOKJUNG
权利人:UNIV RICE WILLIAM M
摘要:This disclosure generally relates to the use of enzyme combinations or recombinant microbes comprising same to make isoprenoid precursors, isoprenoids and derivatives thereof including prenylated aromatic compounds. Novel metabolic pathways exploiting Claisen, aldol, and acyioin condensations are used instead of the natural mevalonate (MVA) pathway or 1-deoxy-d-xylulose 5-phosphate (DXP) pathways for generating isoprenoid precursors such as isopentenyl pyrophosphate (IPP), dimethylallyl pyrophosphate (DMAPP), and geranyl pyrophosphate (GPP). These pathways have the potential for better carbon and or energy efficiency than native pathways. Both decarboxylative and non-carboxylative condensations are utilized, enabling product synthesis from a number of different starting compounds. These condensation reactions serve as a platform for the synthesis of isoprenoid precursors when utilized in combination with a variety of metabolic pathways and enzymes for carbon rearrangement and the addition/removal of functional groups. Isoprenoid alcohols are key intermediary products for the production of isoprenoid precursors in these novel synthetic metabolic pathways.

专利号:US-12018313-B2
优先权日:2016-12-28
标题:Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles
发明人：EMBREE MALLORY
权利人:NATIVE MICROBIALS INC
摘要:Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles, including dosed microbial ensembles and inoculative microbial ensembles, are disclosed.

专利号:US-2018105838-A1
优先权日:2015-03-11
标 题:Process for de novo microbial synthesis of terpenes
发明人：SCHRADER JENS; BUCHHAUPT MARKUS; SONNTAG FRANK; KRONER CORA; BRÃœSER HEIKE; Schröder Hartwig; PELZER RALF
权利人:BASF SE
摘要:The invention relates to microbial terpene production. Known methods for microbial production of terpenes are mostly based on the direct conversion of sugars. Therefore alternative substrates, in particular alternative carbon sources, for use in microbial terpene production were desirable. The invention relates to a methylotrophic bacterium containing recombinant DNA coding for at least one polypeptide with enzymatic activity for heterologous expression in said bacterium, wherein said at least one polypeptide with enzymatic activity is selected from the group consisting an enzyme of a heterologous mevalonate pathway, a heterologous terpene synthase and optionally a heterologous synthase of a prenyl diphosphate precursor. The invention further relates in particular to a method for de novo microbial synthesis of sesquiterpenes or diterpenes from methanol and/or ethanol.

专利号:WO-2024042405-A1
优先权日:2022-08-26
标 题:Compositions and methods for the synthesis of bio-based polymers
发明人：OLIVEIRA ANA; CAPÊTO ANA PAULA; PINTADO MANUELA
权利人:AMYRIS BIO PRODUCTS PORTUGAL UNIPESSOAL LTDA; UNIV CATOLICA PORTUGUESA
摘要:The present disclosure provides compositions and methods for the synthesis of bio-based polymers (e.g., polyurethanes and polyesters) from secondary materials produced during a fermentation process. The disclosure also features intermediates produced during these processes, as well as compositions containing the same.

专利号:WO-2015030681-A1
优先权日:2013-08-30
标题:In vitro synthetic multi-biocatalytic system for the synthesis of isoprenoids and isoprenoid precursors
发明人：TOO HENG PHON; CHEN XIXIAN; ZOU RUIYANG; ZHANG CONQIANG
权利人:UNIV SINGAPORE
摘要:Disclosed herein are in vitro multi-biocatalytic systems for the synthesis of isoprenoid precursors and isoprenoids, as well as methods of producing isoprenoid precursors or isoprenoids in vitro using the systems disclosed herein.

专利号:US-9113653-B2
优先权日:2011-08-19
标题:Methods of administering probiotic organisms that synthesize carotenoid compounds in situ to enhance human health and nutrition
发明人：MARANZ STEVEN J
权利人:MARANZ STEVEN J
摘要:A method is disclosed for increasing systemic carotenoid levels in humans through oral consumption of tablets, capsules, food or beverage products containing microbial organisms capable of synthesizing carotenoid compounds. Carotenoid synthesis may occur in situ by microbial organisms colonizing the gut, or in food or beverage products where carotenoids accumulate and are subsequently consumed dietarily. The microbial organisms may be either transgenic—thus expressing genes in the carotenoid synthesis pathway derived from other microbial organisms, or they may comprise species or strains selected for natural synthesis of carotenoids. The central objective of the invention is to provide an improvement in human health through a novel method for supplying and delivering carotenoid compounds.