CAS: 174732-59-3; 2-Amino-3-(3-Fluoro-4-Methylphenyl)Propanoic Acid

该化合物是一种氟芳烃氨基酸衍生物,可能用于制药和生化研究,其结构以氟替代物和苯环上的甲基组为主,增强了其作为改变peptide和药物设计的一个构件的效用.氟原子引入了电子和...

英文名称2-Amino-3-(3-Fluoro-4-Methylphenyl)Propanoic Acid
中文名称2-氨基-3-(3-氟-4-甲基苯基)丙酸
其它别名3-氟-4-甲基-Dl-苯丙氨酸
CAS编号174732-59-3
MFCD编号:MFCD09832258
分子式:C10H12FNO2分子量:197.21
产品CID: 891996
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: MUTNDIMQYVVGMX-UHFFFAOYSA-N
1S/C10H12FNO2/c1-6-2-3-7(4-8(6)11)5-9(12)10(13)14/h2-4,9H,5,12H2,1H3,(H,13,14)
计算化学: 氢键受体数2.0氢键供体数2.0可旋转键数3.0

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H315-H319-H335
防范说明P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

上下游产品

2-Acetylamino-2-(3-fluoro-4-methylbenzyl)malonic acid diethyl ester

合成工艺路线路线简述

📜2-Acetylamino-2-(3-Fluoro-4-Methylbenzyl)Malonic Acid Diethyl Ester置于盐酸,水体系中,化学反应 0.17H,以86%的收率获得3-氟-4-甲基-Dl-苯丙氨酸
参考文献:Microwave-Assisted Synthesis Of Unnatural Amino Acids
标题:Microwave-Assisted Synthesis Of Unnatural Amino Acids
摘要:Microwave Irradiation Has Been Proven To Be A Useful Tool In The Rapid Assembly Of Racemic Unnatural Amino Acids In Only Two Steps. Additional Benefits Of This Methodology Are The Commercial Availability Of The Inexpensive Starting Materials And The High Yields And High Purities Of The Final Amino Acid Products. (C) 2008 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Bmcl.2008.09.025